Genetic Engineering News and Research

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WVU researcher unravels role of STAT5 protein in the development of multiple sclerosis

A human immune system is a lot like the board game Mouse Trap: it's a Rube Goldberg system of interacting parts. Only instead of a falling ball causing a tiny diver to leap into a tub - which, in turn, springs a trap on some plastic mice - proteins trigger other proteins to activate immune cells and direct them toward germs.

22 Mar 2022

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

The immune system deteriorates with age, making COVID-19 particularly deadly in older people - but to date, no clinically available medication addresses this key risk factor.

21 Mar 2022

A single gene can control brain cell growth in humans, research shows

Controlling how cells grow is fundamental to ensuring proper brain development and stopping aggressive brain tumors.

19 Mar 2022

Study: Targeting astrocytes reduces tau-related brain damage and inflammation in mice

Alzheimer's disease is the most common and best known of the tauopathies, a set of neurodegenerative brain diseases caused by toxic tangles of the protein tau.

18 Mar 2022

Covalent protein nanobodies for neutralizing SARS-CoV-2 and its variants

Researchers developed covalent nanobodies to neutralize severe acute respiratory syndrome coronavirus-2 and its variants.

18 Mar 2022

Researchers find turbocharger for memory in the brain cells of mice

Scientists have long known that learning requires the flow of calcium into and out of brain cells. But researchers at Columbia's Zuckerman Institute have now discovered that floods of calcium originating from within neurons can also boost learning.

17 Mar 2022

Excessive neuropeptide secretion in the lungs can lead to fluid buildup and poor oxygenation

COVID-19 has put a spotlight on the pulmonary and nervous systems, but there is still much to learn about how they interact. Researchers at University of California San Diego School of Medicine recently explored this relationship in the context of a childhood lung disease, but their findings may also apply to COVID-19 symptoms.

17 Mar 2022

Researchers receive grant to find answers to taste loss in COVID patients

Up to 80% of individuals who've had COVID-19 report temporary or lasting changes in their sense of taste, and scientists are working to better understand the biological basis of why, including whether our taste buds are a direct virus target.

15 Mar 2022

First genetic rat model of Down syndrome offers better understanding of the condition

In pursuit of better ways to test new therapies and further explore the impacts of the unique genetics associated with Down syndrome, researchers at Johns Hopkins Medicine and Tottori University in Japan have genetically engineered and characterized what is believed to be the first rat model of Down syndrome.

14 Mar 2022

Multi-institutional teams awarded grant support from the Starr Cancer Consortium

Two multi-institutional teams led by Weill Cornell Medicine scientists have been awarded grant support from the Starr Cancer Consortium. Both grants will fund work applying new technologies to develop more detailed knowledge of tumor biology, with one team focusing on Hodgkin lymphoma and the other on the purity of tumor samples on pathology slides.

10 Mar 2022

Clinical trial of novel rabies vaccine in human volunteers begins in Tanzania

The University of Oxford and the Ifakara Health Institute today announced the vaccination of the first participants in a Phase Ib/II trial testing a novel rabies vaccine in human volunteers in Tanzania.

9 Mar 2022

Single protein elicits multilineage reprogramming of astrocytes in adult mouse brains

A single protein can reverse the developmental clock on adult brain cells called astrocytes, morphing them into stem-like cells that produce neurons and other cell types, UT Southwestern researchers report in a PNAS study.

9 Mar 2022

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that the lower expression of EXOSC2 human protein safeguards from clinical coronavirus disease 2019 (COVID-19). This protective effect was via the reduced EXOSC2 expression-associated suppression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication.

9 Mar 2022

Researchers unravel how parent's gene impact the behavior of children

Parenting is not the only way moms and dads impact the behavior of their offspring. Genes matter, too. And although most of our genes are inherited in pairs - one copy from each parent - moms and dads exert their genetic influence in different ways.

8 Mar 2022

Study reveals new insights on how immune system cells respond to disease-causing pathogens

In laboratory experiments involving a class of mutations in people with a rare collection of immune system disorders, Johns Hopkins Medicine researchers say they have uncovered new details about how immune system cells respond to disease-causing bacteria, fungi and viruses such as SARS-CoV-2.

8 Mar 2022

Manipulating carotenoids can improve plant growth, stress tolerance and increase yield

Manipulating the content of carotenoids, such as ß-carotene, has been found to improve plant growth and increase yield and tolerance to abiotic stresses such as drought and salinity.

7 Mar 2022

Study identifies new ways to enhance SC-beta cell survivability through genetic manipulation

Recent advances in the transplantation of stem cell-derived insulin-producing beta cells (SC-beta cells) to treat type 1 diabetes (T1D) has generated considerable interest and excitement.

3 Mar 2022

New technology can assist bioprosthetic heart valve patients by avoiding additional replacement surgery

An international study led by a researcher from Tel Aviv University offers a novel technology that can assist many patients implanted with bioprosthetic heart valve by avoiding additional complicated replacement surgery.

1 Mar 2022

Unexpected discovery could open the door to new treatment for small-cell lung cancer

An unexpected discovery at UVA Cancer Center has allowed scientists to halt the development of small-cell lung cancer in lab mice, and the surprise finding could open the door to a new treatment approach in people.

25 Feb 2022

Pioneering technique uses a magnetic device to stimulate touch sensitive brain glial cells

Scientists at UCL have developed a new technique that uses microscopic magnetic particles to remotely activate brain cells; researchers say the discovery in rats could potentially lead to the development of a new class of non-invasive therapies for neurological disorders.

24 Feb 2022

Genetic Engineering News and Research

WVU researcher unravels role of STAT5 protein in the development of multiple sclerosis

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

A single gene can control brain cell growth in humans, research shows

Study: Targeting astrocytes reduces tau-related brain damage and inflammation in mice

Covalent protein nanobodies for neutralizing SARS-CoV-2 and its variants

Researchers find turbocharger for memory in the brain cells of mice

Excessive neuropeptide secretion in the lungs can lead to fluid buildup and poor oxygenation

Researchers receive grant to find answers to taste loss in COVID patients

First genetic rat model of Down syndrome offers better understanding of the condition

Multi-institutional teams awarded grant support from the Starr Cancer Consortium

Clinical trial of novel rabies vaccine in human volunteers begins in Tanzania

Single protein elicits multilineage reprogramming of astrocytes in adult mouse brains

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

Researchers unravel how parent's gene impact the behavior of children

Study reveals new insights on how immune system cells respond to disease-causing pathogens

Manipulating carotenoids can improve plant growth, stress tolerance and increase yield

Study identifies new ways to enhance SC-beta cell survivability through genetic manipulation

New technology can assist bioprosthetic heart valve patients by avoiding additional replacement surgery

Unexpected discovery could open the door to new treatment for small-cell lung cancer

Pioneering technique uses a magnetic device to stimulate touch sensitive brain glial cells

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