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New scLS algorithm advances gene expression trajectory analysis

Single-cell RNA sequencing (scRNA-seq) is a method to measure gene expression of individual cells, allowing observation of various cellular processes, including cell differentiation, the cell cycle, and stimulus-response for each unique cell instead of averaging across millions of cells.

1 Sep 2026

Antiviral COVID-19 drug shows no benefit for Long COVID

Results from a clinical trial funded by the National Institutes of Health (NIH) and published today in the journal Lancet Infectious Diseases show that the antiviral drug, PAXLOVID, commonly prescribed to treat acute COVID-19, does not have an impact on Long COVID symptoms when compared to placebo.

1 Sep 2026

Aerobic exercise boosts executive function in postmenopausal women

Regular aerobic exercise – the kind that gets your heart pumping – can improve important thinking skills called executive functions, and the benefits appear especially strong for women after menopause, according to Rutgers researchers.

31 Aug 2026

Semaglutide did more than cut weight in this analysis of 6,239 adults

A systematic review and meta-analysis of nine randomized controlled trials involving 6,239 adults with overweight or obesity without diabetes found that subcutaneous semaglutide produced substantially greater reductions in body weight, waist circumference, and C-reactive protein than placebo. The higher dose of 7.2 mg semaglutide showed potential for greater weight loss, although the evidence is largely based on a single trial and requires confirmation.

31 Aug 2026

Social media messages could empower parents to prevent teen vaping

Parents are an important line of defense against teen vaping, yet many lack the knowledge and tools needed to recognize vaping products, understand their risks and prevent their children from using them.

31 Aug 2026

CAC-based statin initiation shows no difference in major cardiovascular events

There was no difference in major cardiovascular events when statin initiation was based on coronary artery calcium compared with traditional risk factor assessment, according to results presented in a Hot Line session today at ESC Congress 2026.

31 Aug 2026

Precision psychiatry aims to match schizophrenia patients with tailored medicines

Imagine watching a son or daughter begin college during a formative time in life, only to have schizophrenia suddenly alter their reality.

31 Aug 2026

Catheter-directed thrombolysis improves short-term outcomes in pulmonary embolism patients

In patients with intermediate−high risk pulmonary embolism, catheter-directed thrombolysis improved short-term clinical outcomes compared with standard anticoagulation therapy alone, according to results presented in a Hot Line session today at ESC Congress 2026.

31 Aug 2026

New dual-drug strategy blocks triple-negative breast cancer growth

Triple-negative breast cancer (TNBC) has a frustrating ability to adapt. Although this aggressive form of breast cancer can initially respond well to chemotherapy, cancer cells often find ways to survive, allowing the disease to return and become resistant to treatment.

31 Aug 2026

Routine referral of prostate cancer patients to a cardiovascular specialist fails to cut cardiac events

Men with prostate cancer have a high risk of heart disease, especially when treated with hormone therapy.

31 Aug 2026

UC San Diego researchers win DARPA award to develop improved red blood cells

Researchers at the University of California San Diego School of Medicine have been awarded a contract of up to $11.312 million from the Defense Advanced Research Projects Agency (DARPA) to pursue a high-risk, high-reward research project aimed at developing optimized red blood cells that can temporarily boost human performance and health.

31 Aug 2026

Left atrial appendage closure benefits only high-risk cardiac surgery patients

Results do not support routine closure of the left atrial appendage in all patients undergoing open-heart surgery but those at high stroke risk may benefit.

31 Aug 2026

New BioTAK score accurately identifies Takotsubo syndrome before catheterization

Takotsubo syndrome is an acute heart condition that primarily affects postmenopausal women and is often triggered by severe emotional or physical stress.

31 Aug 2026

New tool predicts heart failure treatment effects on blood pressure, kidney function and serum potassium

A new heart failure (HF) treatment effect calculator could help overcome one of the largest barriers to effective heart failure care by predicting the expected effects of treatment on blood pressure, kidney function and potassium levels.

31 Aug 2026

Older heart attack patients need routine invasive treatment rather than selective care

A routine invasive approach should not be replaced with a more selective approach in older patients with the most common type of heart attack.

31 Aug 2026

Newly discovered lung immune cells could transform future flu vaccine design

Influenza continues to cause major illness each year in the United States, leading to more than 35,000 deaths annually. Children, older adults, pregnant individuals, people with weakened immune systems, and those with chronic conditions such as heart disease, metabolic disorders, and cancer are especially vulnerable.

31 Aug 2026

Early cardiac monitoring reveals hidden arrhythmias in patients with unexplained fainting

Early ECG monitoring initiated in the emergency department (ED) has the potential to transform the care of thousands of patients who attend the ED with unexplained fainting.

31 Aug 2026

Targeted lead placement fails to improve cardiac resynchronization outcomes

Targeted placement of the left ventricular lead did not improve outcomes in patients with heart failure undergoing cardiac resynchronization therapy, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in The Lancet.

31 Aug 2026

Anticoagulation lowers subclinical leaflet thrombosis after TAVI procedure

After transcatheter aortic valve implantation (TAVI), anticoagulation reduced imaging signs of clot formation on the new valve compared with antiplatelet therapy, without compromising safety. This was the main finding of the ACASA-TAVI trial presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in JAMA.

31 Aug 2026

Transcatheter tricuspid valve repair lowers mortality and hospitalizations in high-risk patients

Transcatheter tricuspid valve repair significantly improved clinical outcomes in high-risk patients with severe tricuspid regurgitation, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

31 Aug 2026

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Heart News and Research

New scLS algorithm advances gene expression trajectory analysis

Antiviral COVID-19 drug shows no benefit for Long COVID

Aerobic exercise boosts executive function in postmenopausal women

Semaglutide did more than cut weight in this analysis of 6,239 adults

Social media messages could empower parents to prevent teen vaping

CAC-based statin initiation shows no difference in major cardiovascular events

Precision psychiatry aims to match schizophrenia patients with tailored medicines

Catheter-directed thrombolysis improves short-term outcomes in pulmonary embolism patients

New dual-drug strategy blocks triple-negative breast cancer growth

Routine referral of prostate cancer patients to a cardiovascular specialist fails to cut cardiac events

UC San Diego researchers win DARPA award to develop improved red blood cells

Left atrial appendage closure benefits only high-risk cardiac surgery patients

New BioTAK score accurately identifies Takotsubo syndrome before catheterization

New tool predicts heart failure treatment effects on blood pressure, kidney function and serum potassium

Older heart attack patients need routine invasive treatment rather than selective care

Newly discovered lung immune cells could transform future flu vaccine design

Early cardiac monitoring reveals hidden arrhythmias in patients with unexplained fainting

Targeted lead placement fails to improve cardiac resynchronization outcomes

Anticoagulation lowers subclinical leaflet thrombosis after TAVI procedure

Transcatheter tricuspid valve repair lowers mortality and hospitalizations in high-risk patients

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