Hepatocellular Carcinoma News and Research

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Hepatocellular Carcinoma is a type of adenocarcinoma, the most common type of liver tumor.

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

Study: HCV-exposed infants not adequately screened, despite increased prevalence

Due to the opioid epidemic, hepatitis C virus is increasing among pregnant women, resulting in a greater risk of perinatal transmission and HCV infection among children.

2 May 2018

Study reports decreasing rates of liver transplantation among HCC patients in the U.S.

Patients with hepatocellular carcinoma (HCC) waiting for a liver transplant in the USA are now significantly less likely to receive a new liver than they were around a decade ago. A nationwide study presented today at The International Liver Congress™ 2018 in Paris, France, has confirmed that patients with HCC on the liver transplant list in the USA were more than 50% less likely to receive a transplant in 2014-2016 than they were in 2005-2007.

13 Apr 2018

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

The first results from the POISE biopsy sub-study have today confirmed that long-term treatment with obeticholic acid leads to the reversal or stabilization of fibrosis/cirrhosis in patients with primary biliary cholangitis who have had an incomplete response to ursodeoxycholic acid.

13 Apr 2018

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

The final results of the palliative cohort of the SORAMIC study in patients with unresectable, locally advanced primary liver cancer have confirmed no clinical advantage to adding selective internal radiation therapy to standard sorafenib treatment compared with using sorafenib alone.

13 Apr 2018

New, sensitive HBV assay may allow earlier detection of hepatocellular carcinoma

Chronic hepatitis B virus (HBV) can progress to cirrhosis and hepatocellular carcinoma (HCC). A study published in The Journal of Molecular Diagnostics describes a new HBV assay that offers advantages over currently used methods because it has the capability to detect closed circular DNA (cccDNA) in serum, single cells, and preserved tissue samples.

12 Apr 2018

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Kandice Fogle, 43, had just moved to Houston when she began experiencing pain in her back and groin. After undergoing a CT scan, doctors found a large mass in her liver. A biopsy confirmed that she had intrahepatic cholangiocarcinoma, more commonly known as bile duct cancer.

11 Apr 2018

Salk scientists discover protein that 'turns off' uncontrolled liver cancer growth

Salk Institute scientists, together with researchers from Switzerland's University of Basel and University Hospital Basel, discovered a protein called LHPP that acts as a molecular switch to turn off the uncontrolled growth of cells in liver cancer.

29 Mar 2018

Alcohol-related liver cancer may have poor prognosis than other types

A new study indicates that patients with alcohol-related liver cancer often do not live as long as patients with liver cancer that is not associated with alcohol consumption, mainly due to diagnoses at later stages.

28 Mar 2018

Scientists discover rare childhood liver cancer's ability to metastasize to the brain

A surprising finding by Rockefeller University scientists about a rare liver cancer's behavior could lead to more comprehensive patient monitoring and hopefully better outcomes.

19 Mar 2018

Researchers develop method to identify splicing-based biomarkers for liver cancer

Because liver cancer is particularly diverse, genetically, and prone to relapse, identifying biomarkers that can predict disease progression is a critical goal in the fight against it.

2 Mar 2018

New scanning technology could reduce number of biopsies on people with fatty liver disease

A study jointly led by the University of Birmingham and University of Edinburgh has revealed that a new scanning technology could almost halve the number of liver biopsies carried out on people with fatty liver disease.

13 Feb 2018

Testing for alpha fetoprotein may improve early liver cancer detection, finds study

A new study found that ultrasound imaging in combination with a blood test for alpha fetoprotein improved the detection of early-stage liver cancer by 40%.

12 Feb 2018

Combining ultrasound with blood test improves detection of liver cancer by 40%

Combining ultrasound imaging with a blood test for high alpha fetoprotein levels improves detection of early-stage liver cancer by as much as 40 percent, researchers at UT Southwestern's Simmons Cancer Center found.

11 Feb 2018

New AASLD guideline focuses on improving diagnosis, treatment of liver cancer and NAFLD

A new Practice Guideline and Practice Guidance in Hepatology will help improve the diagnosis and treatment of patients with liver cancer as well as patients with non-alcoholic fatty liver disease (NAFLD), which can lead to liver cancer and is characterized by the build-up of extra fat in liver cells often due to obesity and diabetes.

27 Jan 2018

Drinking during late adolescence could be first step to liver problems in adulthood

Alcohol is the leading cause of liver cirrhosis and liver-related deaths. Results of a large long-term study in Sweden have confirmed that drinking during late adolescence could be the first step towards liver problems in adulthood and that guidelines for safe alcohol intake in men might have to be revised downwards, reports the Journal of Hepatology.

22 Jan 2018

Nanobiotix receives FDA approval for first immuno-oncology trial

NANOBIOTIX, a late clinical-stage nanomedicine company pioneering new approaches to the treatment of cancer, today announced the U.S. Food and Drug Administration has approved its Investigational New Drug Application for NBTXR3, a first-in-class nanoparticle designed for direct injection into cancerous tumors, activated by stereotactic ablative radiotherapy (SABR) and administered in combination with an anti-PD1 antibody (nivolumab or pembrolizumab).

26 Dec 2017

Research findings offer prime drug targets to treat rare liver cancer that strikes young people

After years of rigorous research, a team of scientists has identified the genetic engine that drives a rare form of liver cancer. The findings offer prime targets for drugs to treat the usually lethal disease, fibrolamellar hepatocellular carcinoma (FL-HCC), which mainly strikes adolescents and young adults.

22 Nov 2017

Daily aspirin therapy linked to reduced risk of HBV‐related liver cancer

A new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that daily aspirin therapy was significantly associated with a reduced risk in hepatitis B virus‐related liver cancer.

20 Oct 2017

Study documents gene mutation as cause of cancer form in the liver

There is no effective treatment for the cancer form found in the liver called fibrolamellar hepatocellular carcinoma, which is mainly found among children and young people.

12 Oct 2017

Hepatocellular Carcinoma News and Research

Further Reading

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Study: HCV-exposed infants not adequately screened, despite increased prevalence

Study reports decreasing rates of liver transplantation among HCC patients in the U.S.

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

New, sensitive HBV assay may allow earlier detection of hepatocellular carcinoma

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Salk scientists discover protein that 'turns off' uncontrolled liver cancer growth

Alcohol-related liver cancer may have poor prognosis than other types

Scientists discover rare childhood liver cancer's ability to metastasize to the brain

Researchers develop method to identify splicing-based biomarkers for liver cancer

New scanning technology could reduce number of biopsies on people with fatty liver disease

Testing for alpha fetoprotein may improve early liver cancer detection, finds study

Combining ultrasound with blood test improves detection of liver cancer by 40%

New AASLD guideline focuses on improving diagnosis, treatment of liver cancer and NAFLD

Drinking during late adolescence could be first step to liver problems in adulthood

Nanobiotix receives FDA approval for first immuno-oncology trial

Research findings offer prime drug targets to treat rare liver cancer that strikes young people

Daily aspirin therapy linked to reduced risk of HBV‐related liver cancer

Study documents gene mutation as cause of cancer form in the liver

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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