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How chromatin compartmentalization affects DNA damage response

Researchers uncover novel insights into how chromatin compartmentalization influences the DNA damage response (DDR) after double-stranded breaks (DSBs), shedding light on the mechanisms behind genomic integrity maintenance and the risk of translocations. Their findings reveal the importance of chromosomal design in DNA repair and the potential implications for genome stability and cancer translocations.

22 Oct 2023

New method uses extracellular vesicles to enhance immunotherapy responses in glioblastoma

A team of researchers at The University of Texas MD Anderson Cancer Center has developed a new method for using extracellular vesicles to enhance responses to immunotherapy in glioblastoma, potentially opening the door for wider use of engineered messenger RNA (mRNA) for cancer therapy.

19 Oct 2023

Researchers profile new drug combinations to fight antibiotic-resistant bacteria

Antimicrobial resistance – occurring when pathogens can survive antibiotic treatment – is one of the most rapidly emerging global public health threats today.

19 Oct 2023

New TB treatments tackle the disease without wrecking your microbiome

Researchers in a study published in The Lancet Microbe examined how various tuberculosis treatment regimens affect the respiratory microbiome. They found that certain treatments control tuberculosis effectively while minimally impacting the diversity and health of the respiratory microbiome.

15 Oct 2023

SPRI beads offer a viable method for recovering full-length 16S rDNA amplicons

Announcing a new article publication for Zoonoses journal. Solid-phase reversible immobilization (SPRI) beads are widely used for high-throughput sequencing library construction to purify and recover nucleic acids.

13 Oct 2023

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

The intricate interactions between gut microbiota and drugs.

11 Oct 2023

Progress and challenges in completing the human gene catalogue

A group of authors reviewed the progress and challenges in annotating the human genome, including protein-coding genes, isoforms, and non-coding RNAs, and advocated for a universal annotation standard for clinical use.

5 Oct 2023

Sphere Fluidics’ Cyto-Mine system selected by FairJourney Biologics to advance cell line development workflows

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, today announced the Cyto-Mine® platform has been selected by FairJourney Biologics, a world leading end-to-end antibody partner, providing integrated services across antibody discovery, engineering, and production, to expand its cell line development capabilities.

From Fluidic Sciences and Sphere Bio 4 Oct 2023

Ubiquigent collaborates with Imperial College London on DUB probe discovery to facilitate preclinical and clinical target engagement studies

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a PhD student in the Institute of Chemical Biology EPSRC Centre for Doctoral Training (CDT) in Chemical Biology, at Imperial College London.

From Ubiquigent Limited 4 Oct 2023

Unlocking hope for mitochondrial disorders with INTEGRA Biosciences’ electronic pipette

INTEGRA Biosciences’ VOYAGER adjustable tip spacing pipette to support their research on mitochondrial diseases.

From INTEGRA Biosciences 2 Oct 2023

HMS researcher to lead $104 million effort to study bacteria and antibiotic resistance

Harvard Medical School researcher Johan Paulsson will lead a multi-institutional $104 million effort to study bacteria and antibiotic resistance, the U.S. Department of Health and Human Services announced today.

27 Sep 2023

SRI spins off a biosciences platform that accelerates drug discovery

SRI International announced today it is spinning off Synfini, a biosciences platform that accelerates the process by which pharmaceutical and other companies can design, synthesize, and bring to market molecules for drug development.

26 Sep 2023

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers explore the role of the CaMKK2 signaling pathway in bipolar disorder, suggesting it as a new treatment target. By targeting this enzyme, scientists aim to develop more effective therapies for bipolar symptoms and metabolic dysfunction.

24 Sep 2023

CD1 lipidomes exhibit size-based antigen display mechanisms

Study uncovers the complexities of how CD1 molecules present a vast array of lipids to T-cells, revealing a unique, size-based antigen-display system. The findings could provide crucial insights into the intricacies of immune response and antigen presentation.

21 Sep 2023

Study offers new insight into immune cells critical to successful vaccination against SARS-CoV-2

A study has revealed new details about a key population of immune system cells critical to successful vaccination against the pandemic virus, SARS-CoV-2.

21 Sep 2023

Waters launches new walk-up solutions that further simplify the analysis of biologic drug product and cell culture media

Waters Corporation announced new bioprocess walk-up solutions designed to further simplify biologic sample prep and analysis.

From Waters Corporation 19 Sep 2023

Introducing Meteor™ chips on the IsoSpark™ platform: Advancing handsfree quantitative proteomics

We are pleased to introduce Meteor™ chips on the IsoSpark™ platform.

From Bruker Cellular Analysis 18 Sep 2023

MGI partners with National Cancer Centre Singapore to undergo comprehensive genomic profiling of Asian-Prevalent cancers

MGI Tech Singapore Pte, Ltd. ("MGI"), a company committed to building core tools and technology to lead life science, recently entered a research partnership with National Cancer Centre Singapore ("NCCS") to facilitate comprehensive, multi-dimensional genomic profiling of Asian-prevalent cancers using MGI's core DNBSEQ™ technology.

From MGI 18 Sep 2023

MGI and Bio-Medical Science sign MOU to deliver cutting-edge sequencing platforms and reagents to South Korea

MGI, a company committed to building core tools and technology to lead life science, today announced MOU with Bio-Medical Science Co., Ltd. ("BMS") to expand genomics solutions in South Korea by leveraging MGI's cutting-edge technology.

From MGI 18 Sep 2023

MGI's innovative technologies Is enabling sequencing of first plant species in the African BioGenome project

MGI, a company committed to building core tools and technology to lead life science, is delighted to support The African BioGenome Project (AfricaBP), launched in 2021, in sequencing of the project's first plant species based on MGI's DNBSEQ-G400* versatile benchtop sequencer and single-tube long fragment read (stLFR) technology.

From MGI 18 Sep 2023

High Throughput News and Research

How chromatin compartmentalization affects DNA damage response

New method uses extracellular vesicles to enhance immunotherapy responses in glioblastoma

Researchers profile new drug combinations to fight antibiotic-resistant bacteria

New TB treatments tackle the disease without wrecking your microbiome

SPRI beads offer a viable method for recovering full-length 16S rDNA amplicons

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

Progress and challenges in completing the human gene catalogue

Sphere Fluidics’ Cyto-Mine system selected by FairJourney Biologics to advance cell line development workflows

Ubiquigent collaborates with Imperial College London on DUB probe discovery to facilitate preclinical and clinical target engagement studies

Unlocking hope for mitochondrial disorders with INTEGRA Biosciences’ electronic pipette

HMS researcher to lead $104 million effort to study bacteria and antibiotic resistance

SRI spins off a biosciences platform that accelerates drug discovery

Could CaMKK2 enzyme be the key to treating bipolar disorder?

CD1 lipidomes exhibit size-based antigen display mechanisms

Study offers new insight into immune cells critical to successful vaccination against SARS-CoV-2

Waters launches new walk-up solutions that further simplify the analysis of biologic drug product and cell culture media

Introducing Meteor™ chips on the IsoSpark™ platform: Advancing handsfree quantitative proteomics

MGI partners with National Cancer Centre Singapore to undergo comprehensive genomic profiling of Asian-Prevalent cancers

MGI and Bio-Medical Science sign MOU to deliver cutting-edge sequencing platforms and reagents to South Korea

MGI's innovative technologies Is enabling sequencing of first plant species in the African BioGenome project

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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