Medicinal Chemistry News and Research

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New collaboration could lead to novel drugs that address unmet medical needs

Southern Research and the University of Tennessee Health Science Center have formed a partnership to advance promising research that could lead to new drugs that address unmet medical needs.

20 Sep 2017

Molecular life scientists to gather in Jerusalem for 2017 FEBS Congress

Over 1,600 molecular life scientists from over 34 countries, will gather in Jerusalem from September 10-14 for the 2017 Federation of European Biochemical Societies Congress.

11 Sep 2017

Licorice could pose health risk by interacting with medications

Licorice roots have a diverse and flavorful history, having been used in ancient Egyptian times as a tea and in traditional Chinese medicines, all the way to today as a flavoring agent and as an ingredient in some licorice candies.

21 Aug 2017

New discovery could aid in synthesis of radiotracers for use with PET scanning

Researchers have found a surprisingly versatile workaround to create chemical compounds that could prove useful for medical imaging and drug development.

27 Jul 2017

Researchers discover potential chemical 'silver bullet' to reduce risk of colon cancer

In preclinical experiments, researchers at VCU Massey Cancer Center have uncovered a new way in which colon cancer develops, as well as a potential "silver bullet" for preventing and treating it.

26 Jul 2017

New compound takes positive step toward creating drug for melanoma

While past attempts to treat melanoma failed to meet expectations, an international team of researchers are hopeful that a compound they tested on both mice and on human cells in a petri dish takes a positive step toward creating a drug that can kill melanoma cancer cells without harming nearby healthy cells.

26 Jul 2017

Cancer research at University of Warwick receives £8.5k to improve detection, treatments and care

Cancer research at the University of Warwick has received a boost. The University's Cancer Research Centre has been given £8.5k to spend on its research to improve detection, treatments and patient care using the expertise of the University's Warwick Medical School and its partners.

10 Jul 2017

Domainex, Imperial College London expand collaboration to lessen cardiac muscle damage during heart attacks

Domainex Ltd. expands its partnership with Imperial College London, to discover novel therapies that reduce heart muscle damage during heart attacks. The aim is to discover a drug that inhibits the enzyme MAP4K4, which plays a key role in triggering cell death following a heart attack.

19 Jun 2017

Plant compound found to be effective against drug-resistant HIV

A plant found throughout Southeast Asia traditionally used to treat arthritis and rheumatism contains a potent anti-HIV compound more powerful than the drug AZT, according to a new paper published in the Journal of Natural Compounds.

15 Jun 2017

Molecule discovered in worm spit could offer solution for non-healing wounds

Every day 12 Australian diabetics have a limb amputated because of a non-healing wound. Globally, it's one every 30 seconds.

25 May 2017

Research paves way for safer and more effective drugs to treat type 2 diabetes

Research led by the University of Adelaide is paving the way for safer and more effective drugs to treat type 2 diabetes, reducing side effects and the need for insulin injections.

18 May 2017

Natural compound in grape seed extract could increase strength, life of composite-resin fillings

A natural compound found in grape seed extract could be used to strengthen dentin -- the tissue beneath a tooth's enamel -- and increase the life of resin fillings, according to new research at the University of Illinois at Chicago College of Dentistry.

10 May 2017

Study describes synthesis and biological evaluation of novel, effective ARIs

Diabetes mellitus (DM) is probably one of the oldest known diseases and the incidence has been increasing steadily all over the world. This metabolic disease is characterized by chronic hyperglycemia due to defect in insulin secretion and/or insulin action.

17 Apr 2017

TSRI scientists develop easy method for synthesizing compounds with potential to treat lung disorders

Chemists at The Scripps Research Institute have developed a broad and strikingly easy method for synthesizing a class of molecules that have demonstrated value as pharmaceuticals.

17 Apr 2017

KU researcher reveals possible therapeutic intervention for 'chemobrain' in cancer patients

Findings offered by a University of Kansas researcher, identified as one of 20 'Must See Presenters' at the national meeting of the American Chemical Society in early April, suggest a possible therapeutic intervention for "chemobrain," the cognitive impairment plaguing up to a third of cancer patients following chemotherapy.

12 Apr 2017

Researchers design first light-activated drug for treatment of pain

A team of the Institute of Neurosciences of the University of Barcelona has participated in the design of the first light-activated drug -the JF-NP-26, for the treatment of pain, according to a research with animal models published in the journal eLife.

11 Apr 2017

Hebrew University announces launch of new Center for conducting research on cannabinoids

The Hebrew University of Jerusalem has announced the launch of a Multidisciplinary Center on Cannabinoid Research.

5 Apr 2017

Scientists developing new method for drug discovery using simple models and small data sets

Drug discovery is in essence the designing of compounds to interact with disease-related proteins. And in many recent development efforts, this process increasingly relies on "big data" and complex "deep learning", requiring the harnessing of supercomputing power.

29 Mar 2017

Research findings offer potential explanation for opioid-induced itching

Opioids have long been an important tool in the world of pain management, but the side effects of these drugs - from addiction and respiratory failure to severe itching and dizziness, can be overwhelming.

27 Mar 2017

Article focuses on microwave-induced bismuth salts-mediated synthesis of useful organic compounds

Bismuth salts are used as medicinally active ingredients for the past many years due to their minimum toxicity and side effects

25 Mar 2017