Medicinal Chemistry News and Research

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Revolutionary technology could radically change cryopreservation of cells and tissues

Everyone knows that freezing things is an imperfect process. Take frozen food, for example - most have experienced those frozen ice crystals that change the texture and taste of their favorite meal.

6 Feb 2018

Asynt’s DrySyn MAXI heating system used for reproducible scale-up of medicinal chemistry reactions

Asynt reports that medicinal chemistry specialists Charnwood Molecular (Loughborough UK) have been using the DrySyn MAXI heating system to successfully and reproducibly scale up syntheses within their contract research laboratories.

6 Feb 2018

SUTD-NCL team completes phenotypic screening of MMV Malaria Box against pathogenic parasites

A Singapore-India collaborative research project between the Singapore University of Technology & Design and CSIR-National Chemical Laboratories completed phenotypic screening of a large collection of potent chemical inhibitors (known as MMV Malaria Box), against pathogenic parasites Toxoplasma gondii and Plasmodium falciparum, causative agents of human toxoplasmosis and malaria.

27 Jan 2018

Artificial sweetener could lead to development of cancer therapies with less side effects

Artificial sweeteners are used in diet drinks and foods but also could someday be used as treatments targeting carbonic anhydrase IX (CA IX), a protein associated with aggressive cancers.

24 Jan 2018

Potential male birth control pill could be developed from arrow poison

Women have many options for oral contraceptives that are safe, effective and reversible, but despite decades of research, men have none.

18 Jan 2018

KU researchers win $10.8 NIH grant to study cancer, neurological disorders, lung and heart diseases

The University of Kansas' Center for Molecular Analysis of Disease Pathways, a National Institutes of Health Center of Biomedical Research Excellence, recently earned a second phase of grant funding in the amount of $10.8 million for an additional five years.

19 Dec 2017

Researchers receive DoD grant to identify alternatives to opioids for pain management

What does a marine snail's ability to kill prey with two shots of venom have to do with the opioid epidemic ravaging the United States?

29 Nov 2017

Scientists develop potential new antidepressant with unique mechanism of action

A potential new antidepressant and antianxiety treatment with a unique mechanism of action has been developed by scientists at the University of Bath.

6 Nov 2017

Chinese scientists establish synthesis of promising compound to fight against pancreatic cancer

Intriguing antitumor activity is found in a very promising class of natural compounds: cyclic depsipeptides, which have a challenging structure that makes their investigation difficult. Now, Chinese scientists have established the synthesis of a member compound, which is especially promising in killing pancreatic cancer stem cells.

28 Oct 2017

Clarivate Analytics includes eBooks for coverage in Book Citation Index

Clarivate Analytics has recently included the following 16 eBooks for coverage in Book Citation Index. The Book Citation Index in Web of Science™ Core Collection connects a library's book collection to powerful new discovery tools, giving researchers the ability to quickly and easily identify and access the most relevant books.

30 Sep 2017

New collaboration could lead to novel drugs that address unmet medical needs

Southern Research and the University of Tennessee Health Science Center have formed a partnership to advance promising research that could lead to new drugs that address unmet medical needs.

20 Sep 2017

Molecular life scientists to gather in Jerusalem for 2017 FEBS Congress

Over 1,600 molecular life scientists from over 34 countries, will gather in Jerusalem from September 10-14 for the 2017 Federation of European Biochemical Societies Congress.

11 Sep 2017

Licorice could pose health risk by interacting with medications

Licorice roots have a diverse and flavorful history, having been used in ancient Egyptian times as a tea and in traditional Chinese medicines, all the way to today as a flavoring agent and as an ingredient in some licorice candies.

21 Aug 2017

New discovery could aid in synthesis of radiotracers for use with PET scanning

Researchers have found a surprisingly versatile workaround to create chemical compounds that could prove useful for medical imaging and drug development.

27 Jul 2017

Researchers discover potential chemical 'silver bullet' to reduce risk of colon cancer

In preclinical experiments, researchers at VCU Massey Cancer Center have uncovered a new way in which colon cancer develops, as well as a potential "silver bullet" for preventing and treating it.

26 Jul 2017

New compound takes positive step toward creating drug for melanoma

While past attempts to treat melanoma failed to meet expectations, an international team of researchers are hopeful that a compound they tested on both mice and on human cells in a petri dish takes a positive step toward creating a drug that can kill melanoma cancer cells without harming nearby healthy cells.

26 Jul 2017

Cancer research at University of Warwick receives £8.5k to improve detection, treatments and care

Cancer research at the University of Warwick has received a boost. The University's Cancer Research Centre has been given £8.5k to spend on its research to improve detection, treatments and patient care using the expertise of the University's Warwick Medical School and its partners.

10 Jul 2017

Domainex, Imperial College London expand collaboration to lessen cardiac muscle damage during heart attacks

Domainex Ltd. expands its partnership with Imperial College London, to discover novel therapies that reduce heart muscle damage during heart attacks. The aim is to discover a drug that inhibits the enzyme MAP4K4, which plays a key role in triggering cell death following a heart attack.

19 Jun 2017

Plant compound found to be effective against drug-resistant HIV

A plant found throughout Southeast Asia traditionally used to treat arthritis and rheumatism contains a potent anti-HIV compound more powerful than the drug AZT, according to a new paper published in the Journal of Natural Compounds.

15 Jun 2017

Molecule discovered in worm spit could offer solution for non-healing wounds

Every day 12 Australian diabetics have a limb amputated because of a non-healing wound. Globally, it's one every 30 seconds.

25 May 2017