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IntegraGen’s ARISk Test looks at 65 genetic markers associated with autism

IntegraGen, Inc., a biotechnology company dedicated to molecular biomarker discovery, today announced the launch of the ARISk- Risk Assessment Test, a gender specific, genetic screening test that looks at 65 genetic markers associated with Autism Spectrum Disorder.

5 Apr 2012

First study to evaluate treatment based on molecular profiling of advanced pancreatic cancer

The feasibility of selecting treatment based on individual molecular characteristics was demonstrated in a first-of-its kind pancreatic cancer clinical trial reported today by the Translational Genomics Research Institute (TGen) and the Virginia G. Piper Cancer Center at Scottsdale Healthcare.

4 Apr 2012

Infection with dengue virus turns on feeding-related genes in mosquitoes

Researchers at the Johns Hopkins Bloomberg School of Public Health have, for the first time, shown that infection with dengue virus turns on mosquito genes that makes them hungrier and better feeders, and therefore possibly more likely to spread the disease to humans.

30 Mar 2012

TRIM28 protein essential after fertilisation to preserve epigenetic marks on imprinted genes

An international team led by scientists at A*STAR's Institute of Medical Biology (IMB) discovered that a protein, called TRIM28, normally present in the mother's egg, is essential right after fertilisation, to preserve certain chemical modifications or 'epigenetic marks' on a specific set of genes.

30 Mar 2012

Affymetrix' GeneChip technology incorporated into Lineagen's FirstStepDx genetic evaluation service

Affymetrix, Inc. and Lineagen, Inc., an innovative molecular diagnostics company focused on complex, genetically linked disorders, today announced the companies have signed an agreement to incorporate Affymetrix' GeneChip technology into Lineagen's next-generation FirstStepDx, a genetic evaluation service for individuals with developmental delay (DD), intellectual disability (ID), and autism spectrum disorders (ASD).

29 Mar 2012

OriGene releases UltraMAB Antibodies for IHC applications

OriGene Technologies today announced the release of a new line of ultra specific and extensively validated monoclonal antibodies under the UltraMAB brand.

21 Mar 2012

Researchers discover new method to identify cancer-causing translocations

Researchers from Huntsman Cancer Institute (HCI) at the University of Utah report they have discovered a method to identify cancer-causing rearrangements of genetic material called chromosomal translocations quickly, accurately, and inexpensively.

20 Mar 2012

New FSU technology could decrease the cost of drug discovery

New technology being developed at Florida State University could significantly decrease the cost of drug discovery, potentially leading to increased access to high-quality health care and cancer patients receiving personalized chemotherapy treatments.

16 Mar 2012

Study examines mRNA transcripts in the sperm of fruitflies and humans

It had long been assumed that the human sperm cell's mission in life ended once it had transferred its freight of parental DNA to the egg. More recently however, other components of sperm have been implicated in fertilization, and perhaps even in subsequent embryonic development.

1 Mar 2012

Study aims to develop noninvasive method to analyze interstitial cystitis

A pilot study led by University of Kentucky researchers shows that the gene expression analysis of urine sediment could provide a noninvasive way to analyze interstitial cystitis in some patients.

24 Feb 2012

China's SFDA approves Affymetrix GeneChip System 3000Dx v.2

Affymetrix, Inc. today announced that its GeneChip System 3000Dx v.2 (GCS 3000Dx v.2) has been approved by China's State Food and Drug Administration (SFDA) for in vitro diagnostic use.

16 Feb 2012

Agilent's microarrays used in landmark study on prenatal samples

Agilent Technologies Inc. today announced its microarrays were used in a landmark research study on prenatal samples. The three-year study was designed to evaluate the accuracy, efficacy and potential advantages of using microarray analysis as compared with conventional karyotyping. Agilent SurePrint CGH microarrays and analysis software were used for the majority sample cohort of 4,400 samples.

14 Feb 2012

Chromosomal microarray provides more information about fetal abnormalities

A nationwide, federally funded study has found that testing a developing fetus' DNA through chromosomal microarray (CMA) provides more information about potential disorders than does the standard method of prenatal testing, which is to visually examine the chromosomes.

10 Feb 2012

Researchers discover function and expression of CD97 in malignant gliomas

Researchers at Virginia Commonwealth University Medical Center's VCU Massey Cancer Center and Harold F. Young Neurosurgical Center and Old Dominion University have discovered that suppression of Wilms tumor 1 protein (WT1) results in downregulation of CD97 gene expression in three glioblastoma cell lines and reduces the characteristic invasiveness exhibited by glial tumor cells.

8 Feb 2012

Scientists connect two signature characteristics of pancreatic cancer

Scientists have connected two signature characteristics of pancreatic cancer, identifying a self-perpetuating "vicious cycle" of molecular activity and a new potential target for drugs to treat one of the most lehal forms of cancer.

27 Jan 2012

New imaging probes can non-invasively detect breast cancer lymph node metastasis

Using two cell surface markers found to be highly expressed in breast cancer lymph node metastasis, researchers at Moffitt Cancer Center, working with colleagues at other institutions, have developed targeted, fluorescent molecular imaging probes that can non-invasively detect breast cancer lymph node metastasis.

13 Jan 2012

Four-year effort to map genetic code of 1,000 African-Americans

A Johns Hopkins-led team of experts in genetics, immunology, epidemiology and allergic disease has embarked on a four-year effort to map the genetic code, or whole genome, of 1,000 people of African descent, including men and women from Baltimore.

30 Dec 2011

Researchers present results from 31 major studies of blood-related cancers at ASH 2011 meeting

Researchers from the John Theurer Cancer Center at Hackensack University Medical Center, one of the nation's top 50 best hospitals for cancer, presented results from 31 major studies of blood-related cancers - leukemia, lymphoma and multiple myeloma -- during the American Society of Hematology (ASH) Annual Meeting, December 10-13, 2011 in San Diego.

23 Dec 2011

NIH awards $3.2M for development of highly efficient system of generating nucleic acid molecules

The National Institutes of Health (NIH) has awarded $3.2 million to a team of preeminent engineering, chemistry, and biology researchers to develop a highly efficient system of generating nucleic acid molecules, called aptamers.

29 Nov 2011

Uncommon genetic deletions associated with short stature

New research sifts through the entire genome of thousands of human subjects to look for genetic variation associated with height. The results of the study, published by Cell Press in the December issue of the American Journal of Human Genetics, suggest that uncommon genetic deletions are associated with short stature.

24 Nov 2011