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Breakthrough brain training shows promise for Long COVID recovery

Researchers at the University of Alabama at Birmingham (UAB) have identified what is believed to be the first intervention found in a randomized controlled trial to show large and very large improvements in multiple symptoms associated with Long COVID, and to result in people debilitated by those symptoms returning to work.

5 May 2025

TDP-43 dysfunction in brain blood vessels may drive Alzheimer's and ALS progression

Reduced levels of a critical protein are linked to devastating brain diseases like Alzheimer's, frontotemporal dementia, and amyotrophic lateral sclerosis (ALS). Surprisingly, the protein shortage primarily affects the brain's blood vessels.

30 Apr 2025

Higher biological age linked to increased dementia risk

People whose biological age is higher than their chronological age may be more likely to develop dementia than people whose biological age matches or is lower than their chronological age, according to a study published on April 30, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

30 Apr 2025

Researchers discover new biomarker to predict multiple sclerosis progression

Researchers at the University of Turku, Finland, have discovered a new biomarker that can predict the progression of multiple sclerosis (MS).

29 Apr 2025

AI model enhances early diagnosis of multiple sclerosis

To provide the right treatment for MS, it is important to know when the disease changes from relapsing-remitting to secondary progressive, a transition that is currently recognized on average three years too late.

28 Apr 2025

Computational biology uncovers RNA changes in ALS patients

Amyotrophic lateral sclerosis (ALS) is a disease that destroys the nerves necessary for movement. About 30,000 people in the United States are affected, and doctors still don't know what causes it.

25 Apr 2025

Intravenous therapy promotes survival of heart muscle cells after a heart attack

Researchers have developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure.

25 Apr 2025

Metabolic syndrome in midlife linked to higher dementia risk

Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of young-onset dementia, according to a study published on April 23, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

23 Apr 2025

New approach may prevent neurotoxic protein aggregates in ALS

Researchers at Goethe University, Johannes Gutenberg University Mainz and Kiel University discover possible method for preventing protein aggregates – Cluster4Future PROXIDRUGS research project.

23 Apr 2025

Engineered brain cells offer new hope for treating Alzheimer's

A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to University of California, Irvine scientists.

21 Apr 2025

Exploring citrullination as a key regulator of gene expression and disease

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

20 Apr 2025

Using AI to understand how the brain processes language during real-life conversations

We investigated how our brains process language during real-life conversations. Specifically, we wanted to understand which brain regions become active when we're speaking and listening, and how these patterns relate to the specific words and context of the conversation.

18 Apr 2025

Existing drug shows potential to revive immune cells in sepsis patients

When the immune system does not function properly, individuals become more susceptible to infections caused by viruses, bacteria, or fungi.

18 Apr 2025

Discovery sheds light on protein's role in myelin formation and schizophrenia

Research published in the Journal of Neurochemistry has detailed the role of a protein, hnRNP A1, in the formation and stability of myelin, suggesting an important impact on neurodegenerative diseases and mental disorders such as multiple sclerosis and schizophrenia.

17 Apr 2025

2025 Best Practices Update released for managing MS in a changing landscape

Keeping up with scientific advances and practice changes can be one the biggest challenges in managing a complex disease like multiple sclerosis (MS).

17 Apr 2025

Sex and age play key roles in dementia biomarker levels

A new study has found important clues about the roles age, sex, hormonal changes and genetics play in how certain biomarkers for dementia are expressed in the blood, according to a study published on April 16, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

16 Apr 2025

UC researchers receive $200,000 grant to design user-friendly exoskeleton for spinal cord injury patients

For people with spinal cord injuries/diseases (SCI/D), performing daily tasks can be a challenge due to an impaired ability to grasp and manipulate objects with their hands.

16 Apr 2025

Calibr-Skaggs receives FDA approval to test sCAR-T therapy in patients with autoimmune diseases

Calibr-Skaggs Institute for Innovative Medicines, the drug discovery division of Scripps Research, announced today that the FDA has cleared their investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy (CLBR001 + SWI019) in patients with autoimmune conditions.

9 Apr 2025

Heavy drinking linked to increased risk of brain lesions

Heavy drinkers who have eight or more alcoholic drinks per week have an increased risk of brain lesions called hyaline arteriolosclerosis, signs of brain injury that are associated with memory and thinking problems, according to a study published on April 9, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

9 Apr 2025

Study explores impact of parental Alzheimer’s on tau protein spread in the brain

While some studies have suggested that having a mother with Alzheimer's disease may put you more at risk of developing the disease, a new study finds that having a father with the disease may be tied to a greater spread of the tau protein in the brain that is a sign of the disease, according to a study published on April 9, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

9 Apr 2025