Short Chain Fatty Acids News and Research

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Butyrate and propionate are two important short-chain fatty acids (SCFAs) produced in the human gut. They have been shown to have significant immune system effects in the intestinal mucosa, by inducing the differentiation of T-regulatory cells via inhibition of histone deacetylase (HDAC). This enzyme keeps chromatin from unwinding and, therefore, inhibits gene transcription.

Study: Early introduction of solid foods may predispose infants to obesity

Infants who were started on solid foods at or before three months of age showed changes in the levels of gut bacteria and bacterial byproducts, called short-chain fatty acids, measured in their stool samples, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

1 Apr 2020

Presence of certain gut bacterium in mothers could protect babies from food allergies

Researchers have found that bacteria in a mother’s gut during pregnancy can protect the baby from developing food allergies.

25 Mar 2020

Using 'organs-on-a-chip' to study chronic inflammatory diseases

MIT biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system, on a specialized microfluidic platform seeded with human cells.

18 Mar 2020

Diet influences multiple sclerosis disease course

The short-chain fatty acid propionic acid influences the intestine-mediated immune regulation in people with multiple sclerosis (MS).

11 Mar 2020

Research opens up new prospects for prevention and treatment of bacterial pneumonia

Researchers from the Lille Centre for Infection and Immunity, INRAE and from Brazilian (Belo Horizonte), Scottish (Glasgow) and Danish (Copenhagen) laboratories have shown for the first time in mice that perturbation of the gut microbiota caused by the influenza virus favors secondary bacterial superinfection.

3 Mar 2020

Mediterranean diet promotes healthy aging with healthier gut microbiome

A new study published online in the journal Gut in February 2020 reports the striking health-promoting effects of switching to a Mediterranean diet for just one year. The results were due to an increase in the health and number of gut bacteria that favor a healthy diet.

17 Feb 2020

Genomic sequencing technique helps understand gut microbiota one cell at a time

A population of microorganisms living in our intestine, known as the gut microbiota, plays a crucial role in controlling our metabolism and reducing the risk of conditions such as obesity and diabetes.

9 Feb 2020

Gut microbes may play a role in stroke recovery

New research shows that the microorganisms in our gut could help protect brain cells from damage caused by inflammation after a stroke.

8 Jan 2020

Short chain fatty acid supplementation improves stroke recovery, mice study shows

Supplementing the body’s short chain fatty acids can improve stroke recovery, according to research in mice recently published in JNeurosci. Short chain fatty acid supplementation may be a non-invasive addition to stroke rehabilitation therapies.

From Society for Neuroscience 2 Jan 2020

Short-term increases in sugar consumption could raise risk of inflammatory bowel disease

Short-term increases in sugar consumption could increase the risk of inflammatory bowel disease and have a significant impact on our health, a new study out of the University of Alberta suggests.

14 Nov 2019

Bacteriophages could treat E. coli without damaging the gut, new study says

Researchers in the US have developed a new therapy that uses a unique bacteriophage to treat E. coli infections.

13 Nov 2019

Healthiest gut bacteria with plant-based or Mediterranean diet

A new study shows that specific foods that are supplied by either a plant-based or a Mediterranean-type diet can protect the gut against inflammatory disorders, by selectively promoting the growth of anti-inflammatory bacteria.

21 Oct 2019

Prehistoric baby bottles: evidence animal milk fed to prehistoric babies

A new study shows that infants in Bronze and Iron Age communities were fed milk using feeding vessels of clay. This report, appearing on September 25, 2019, in the journal Nature, shows the important place that animal milk has played in human food for thousands of years.

26 Sep 2019

A vegan diet could boost gut microbes that aid weight loss

Switching to a vegan diet could help people lose nearly one pound in weight every week and significantly reduce their risk for diabetes, say researchers.

18 Sep 2019

Gut bacteria linked to stronger muscles in older people

The gut bacteria are related to muscle mass and physical function, in a relationship called the gut-muscle axis, which has been studied in mouse models and in young adults. A new study looks at the GMA in older adults for the first time.

18 Sep 2019

Plant-based diet could heal your rheumatoid arthritis

According to the latest review, adopting a plant-based diet could well relieve the swollen joints and pain of rheumatoid arthritis (RA).

13 Sep 2019

Remodeling unhealthful gut microbiomes with the help of synthetic peptides

You are what you eat - right down to the microbiome living in your gut. Diet can affect which microbes are in the intestinal tract, and research has shown that harmful gut microbiome changes can lead to illnesses such as heart disease, obesity and cancer.

27 Aug 2019

Whole body vibration helps reduce inflammation, thanks to the gut microbiome

Whole body vibration appears to improve many symptoms of type II diabetes mellitus, wherein glucose and destructive inflammation shoots up. The procedure helps the body use glucose as an energy source, and at the same time, modify the microbiome to fight inflammation, a new study says.

6 Aug 2019

Whole body vibration adjusts the microbiome and immune cells to deter inflammation in diabetes

In the face of diabetes, a common condition in which glucose and levels of destructive inflammation soar, whole body vibration appears to improve how well our body uses glucose as an energy source and adjust our microbiome and immune cells to deter inflammation, investigators report.

5 Aug 2019

Chemicals produced by gut microbiome could help identify children at risk of organ failure

Chemicals produced by healthy bacteria could be used to assess the health of the gut microbiome and help identify critically-ill children at greatest risk of organ failure, a study published in Critical Care Medicine has found.

14 Jun 2019