Biomarker News and Research

RSS

A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Japanese researchers discover that 2-aminobutyric acid can effectively raise antioxidant levels

A Japanese research team has become the first in the world to discover that 2-aminobutyric acid (2-AB) is closely involved in the metabolic regulation of the antioxidant glutathione, and that it can effectively raise levels of glutathione in the body when ingested.

15 Dec 2016

Antioxidant levels could be boosted with newly-found amino acid function

14 Dec 2016

New brain scan could act as diagnostic tool in Parkinson’s

A type of brain scan could act as a diagnostic tool in Parkinson’s according to a new study published in the scientific journal Radiology.

9 Dec 2016

New biomarker in cell-free blood plasma linked to overactive stress system in suicidal individuals

Researchers at Lund and Malmö universities in Sweden have measured a biomarker in cell-free blood plasma which can be linked to an overactive stress system in suicidal individuals. This biomarker can hopefully be used in future psychiatric studies.

8 Dec 2016

Stem cell-based risk scoring tool could predict AML patient’s response to standard treatment

Leukemia researchers at Princess Margaret Cancer Centre have developed a 17-gene signature derived from leukemia stem cells that can predict at diagnosis if patients with acute myeloid leukemia (AML) will respond to standard treatment.

8 Dec 2016

PITX2 methylation biomarker shows promise for predicting prostate cancer recurrence risk

Prostate-specific antigen (PSA) and other biomarkers are essential tools for diagnosing and monitoring prostate cancer.

8 Dec 2016

Older women with metastatic breast cancer more likely to have genetic alterations in tumors

A University of North Carolina Lineberger Comprehensive Cancer Center-led analysis has found that women who are 65 years or older with metastatic breast cancer were more likely to have a cancer-linked genetic alterations in their tumors, and had a larger total number of genetic alterations, than younger patients overall.

7 Dec 2016

Study detects biomarkers from secondhand marijuana smoke exposure in children

Relaxing with a joint around children is not very wise. Not only do youngsters inhale harmful secondary smoke in the process, but the psychoactive chemicals in the drug are taken up by their bodies as well.

7 Dec 2016

New chemosensor offers better sensitivity in detecting biomarker for cancer and inflammatory diseases

A new technique offers better sensitivity and accuracy in detecting an essential biomarker of cancer and inflammatory diseases.

7 Dec 2016

Detecting inflammation in diabetic patients

As well as presenting with high blood glucose, diabetic patients have chronic low-grade inflammation, which can be measured by a range of inflammatory markers such as so-called high-sensitive CRP, TNFa and IL-6 as well as a full blood cell count.

7 Dec 2016

PD-1 protein could serve as biomarker for predicting survival of lung cancer patients

The biomarker PD-1, a protein, could potentially be used to predict survival or disease-free survival of lung cancer patients who have had the tumour surgically removed.

6 Dec 2016

Scientists discover new biomarker to help determine aggressiveness of brain cancer

Researchers at UT Southwestern Medical Center have found a new biomarker for glioma, a common type of brain cancer, that can help doctors determine how aggressive a cancer is and that could eventually help determine the best course of treatment.

6 Dec 2016

$Combination treatment produces better outcomes in erythropoietin-refractory MDS patients, study shows$

Combination treatment produces better outcomes in erythropoietin-refractory MDS patients, study shows

Patients with myelodysplastic syndromes (MDS) suffer from a reduction in the number of different types of blood cells, including red blood cells leading to the development of anemia.

4 Dec 2016

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Patients successfully treated for breast, colon and other cancers can go on to develop an often-fatal form of leukemia, sometimes years after completion of treatment, due to a genetic mutation leading to secondary malignancies known as therapy-related myeloid neoplasms (t-MNs).

4 Dec 2016

Researchers show how microRNAs play key role in tumor progression and response to radiation

OHSU researcher Sudarshan Anand, Ph.D., has a contemporary analogy to describe microRNA: "I sometimes compare MicroRNA to tweets -- they're short, transient and constantly changing."

2 Dec 2016

NSF awards grant to advance new diagnostic test for fatal gastrointestinal disease in pre-term infants

The National Science Foundation has chosen an LSU Health New Orleans team that developed a test for the early detection of a potentially life-threatening gastrointestinal disease affecting pre-term, low birthweight babies to receive expert guidance to move the technology forward.

1 Dec 2016

Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Researchers at NEOMED have just identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer's disease (AD).

1 Dec 2016

Aerobic activity offers greater preservation of brain volume, improves cognitive performance

Using a new MRI technique, researchers found that adults with mild cognitive impairment (MCI) who exercised four times a week over a six-month period experienced an increase in brain volume in specific, or local, areas of the brain, but adults who participated in aerobic exercise experienced greater gains than those who just stretched.

30 Nov 2016

Johns Hopkins researchers find evidence of brain injury in young NFL players

In a small study of young or recently retired NFL players, researchers at Johns Hopkins report finding evidence of brain injury and repair that is visible on imaging from the players compared to a control group of men without a history of concussion.

29 Nov 2016

Inflammatory marker detected in blood tests can better predict risk of death, study suggests

A new study looking at deaths from cancer, cardiovascular disease and all causes suggests that an inflammatory marker detected in blood tests in middle-aged adults can better predict the risk of death compared with another similar biomarker.

29 Nov 2016

Biomarker News and Research

Further Reading

Japanese researchers discover that 2-aminobutyric acid can effectively raise antioxidant levels

Antioxidant levels could be boosted with newly-found amino acid function

New brain scan could act as diagnostic tool in Parkinson’s

New biomarker in cell-free blood plasma linked to overactive stress system in suicidal individuals

Stem cell-based risk scoring tool could predict AML patient’s response to standard treatment

PITX2 methylation biomarker shows promise for predicting prostate cancer recurrence risk

Older women with metastatic breast cancer more likely to have genetic alterations in tumors

Study detects biomarkers from secondhand marijuana smoke exposure in children

New chemosensor offers better sensitivity in detecting biomarker for cancer and inflammatory diseases

Detecting inflammation in diabetic patients

PD-1 protein could serve as biomarker for predicting survival of lung cancer patients

Scientists discover new biomarker to help determine aggressiveness of brain cancer

Combination treatment produces better outcomes in erythropoietin-refractory MDS patients, study shows

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Researchers show how microRNAs play key role in tumor progression and response to radiation

NSF awards grant to advance new diagnostic test for fatal gastrointestinal disease in pre-term infants

Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Aerobic activity offers greater preservation of brain volume, improves cognitive performance

Johns Hopkins researchers find evidence of brain injury in young NFL players

Inflammatory marker detected in blood tests can better predict risk of death, study suggests

Event guide: 16th Clinical Biomarkers & CDx Summit Europe eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo