Efficacy News and Research

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World’s first childbirth following a uterus transplantation achieved solely by robot-assisted surgery

For the first time worldwide, in yet another breakthrough by the world-leading research team at the University of Gothenburg, a child has been born following a uterus transplantation achieved solely by robot-assisted surgery on both donor and recipient.

26 May 2023

Is a multicomponent hypertension management program implemented in the public primary care setting associated with fewer patient complications and mortality?

Researchers compared hypertension-associated complications and the use of healthcare services at five years among hypertensive individuals managed using the Risk Assessment and Management Program for Hypertension (RAMP-HT) versus regular care.

26 May 2023

Are inadequate culinary skills among undergraduate students associated with obesity and overweight?

Researchers investigated the association between the culinary skills of undergraduate students and their chances of being obese.

26 May 2023

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2.

26 May 2023

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

Novel vaccine offers hope for defeating epidemic meningitis by 2030

A trial of a new vaccine against meningococcal disease, a cause of meningitis and blood poisoning, has found that it is safe and induces a strong immune response across five strains of meningococcal bacteria: A, C, W, Y and X.

25 May 2023

Case study: Experimental lecanemab treatment causes adverse outcomes in 65-year-old woman with Alzheimer's disease

In a noteworthy case study published in the Journal of Alzheimer's Disease investigators report autopsy findings in a 65-year-old woman with Alzheimer's disease (AD) who received three open label infusions of the experimental anti-amyloid beta (Aβ) antibody drug lecanemab.

25 May 2023

First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses

Researchers from Fred Hutchinson Cancer Center in Seattle, Scripps Research in La Jolla, California, IAVI and other collaborating institutions have characterized robust T-cell responses in volunteers participating in the IAVI G001 Phase 1 clinical trial to test the safety and immune response of a self-assembling nanoparticle HIV vaccine.

25 May 2023

Digital plan of care leads to better outcomes of people living with type 2 diabetes, study shows

Research conducted as part of UKRIs digital health technology catalyst sponsored by Healum Ltd in partnership with Vernova Healthcare CIC, demonstrates that the use of Healum’s mobile app, connected to its care planning software and patient management system for healthcare professionals in primary care, has helped to improve health outcomes, health engagement and quality of life for people living with type 2 diabetes.

25 May 2023

Focusing on satiety and satiation may be better for weight loss success

Researchers hypothesized that focusing on satiety (feeling free of hunger) and satiation (feeling satisfied with a meal) through the consumption of fruits and vegetables may be better targets for weight loss success.

24 May 2023

What is the efficacy, safety, and tolerability of novel danuglipron in adults with type two diabetes?

Researchers assessed the safety and efficacy of danuglipron in type 2 diabetes (T2D) patients.

24 May 2023

CDC reports on its Mpox response

Research paper provides an overview of the U.S. monkeypox outbreak, highlighting the rapid response, vaccination efforts, and racial disparities in cases. Ongoing surveillance, vaccination, and communication are emphasized as crucial for future prevention.

24 May 2023

Oral antivirals Molnupiravir and Nirmatrelvir-Ritonavir lower COVID-19 risks in type 2 diabetes patients

Research investigates the effectiveness of oral antiviral medications, Molnupiravir and Nirmatrelvir-Ritonavir, in treating patients with type 2 diabetes and mild to moderate COVID-19. The study aims to determine the efficacy of these medications in reducing adverse outcomes in this specific population.

24 May 2023

Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

The antimicrobial potential of nanoparticles

Nanoparticles have widely been used as advanced tools for the diagnosis, prevention, and treatment of infectious diseases.

23 May 2023

International clinical trial to evaluate new combinations of generic antibiotics for treating neonatal sepsis

An international clinical trial co-led by UCL (University College London) researchers will evaluate much-needed new antibiotic combinations for newborn babies with sepsis.

23 May 2023

Transcatheter edge-to-edge procedure to repair leaky mitral valves found to be safe and effective

Long-awaited outcomes data of transcatheter edge-to-edge procedures to repair patients' leaky mitral valves revealed the minimally invasive procedure to be safe and effective in nearly 90% of patients, according to Cedars-Sinai physician-scientists.

23 May 2023

New trial data validates a rapid diagnostic test for sepsis

Critical care physician Hollis O'Neal, MD, MSc, Associate Professor of Medicine at LSU Health New Orleans School of Medicine's Baton Rouge campus, presented data that validate a rapid diagnostic test for sepsis at the American Thoracic Society 2023 International Conference.

23 May 2023

Real-world assessment of JYNNEOS vaccine effectiveness during the 2022 mpox outbreak in the US

A recent study published in Morbidity and Mortality Weekly Report estimated the efficacy of the JYNNEOS vaccine against mpox.

22 May 2023

New clinical trial gets underway to evaluate new antibiotic combinations for newborns with sepsis

An international clinical trial to evaluate much-needed new antibiotic combinations for newborn babies with sepsis has started in three public hospitals in South Africa and Kenya.

22 May 2023

Efficacy News and Research

World’s first childbirth following a uterus transplantation achieved solely by robot-assisted surgery

Is a multicomponent hypertension management program implemented in the public primary care setting associated with fewer patient complications and mortality?

Are inadequate culinary skills among undergraduate students associated with obesity and overweight?

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Novel vaccine offers hope for defeating epidemic meningitis by 2030

Case study: Experimental lecanemab treatment causes adverse outcomes in 65-year-old woman with Alzheimer's disease

First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses

Digital plan of care leads to better outcomes of people living with type 2 diabetes, study shows

Focusing on satiety and satiation may be better for weight loss success

What is the efficacy, safety, and tolerability of novel danuglipron in adults with type two diabetes?

CDC reports on its Mpox response

Oral antivirals Molnupiravir and Nirmatrelvir-Ritonavir lower COVID-19 risks in type 2 diabetes patients

Looking at cancer drugs to help put the brakes on classic indicators of aging

The antimicrobial potential of nanoparticles

International clinical trial to evaluate new combinations of generic antibiotics for treating neonatal sepsis

Transcatheter edge-to-edge procedure to repair leaky mitral valves found to be safe and effective

New trial data validates a rapid diagnostic test for sepsis

Real-world assessment of JYNNEOS vaccine effectiveness during the 2022 mpox outbreak in the US

New clinical trial gets underway to evaluate new antibiotic combinations for newborns with sepsis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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