Genetic Engineering News and Research

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Study reveals white blood cells can both hurt and help transplanted kidneys

In an example of biological irony, the same white blood cell chemistry known to damage kidneys used for transplants may also help prevent such damage, according to a federally funded study in genetically engineered mice at Johns Hopkins.

21 Sep 2006

Reproductive technologies and designer babies

The well-educated are significantly more open to the idea of "designing" babies than the poorly educated, according to a new study by psychologists at the University of East Anglia.

5 Sep 2006

Induction of potent antitumor immunity by intratumoral injection of IL-23 transduced dendritic cells

One therapy for treating brain tumors alerts the immune system to the presence of foreign material. A second therapy enhances the first and prolongs the immune system's response.

4 Sep 2006

Mature muscle fibers can revert to become cancerous

Mature muscle fibers, rather than their less-developed neighbors, are the tissues that turn malignant in a soft-tissue cancer that strikes children and teens, researchers at UT Southwestern Medical Center and Children's Medical Center Dallas have found.

4 Sep 2006

New method of gene therapy alters immune cells for treatment of advanced melanoma

A team of researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, has demonstrated sustained regression of advanced melanoma in a study of 17 patients by genetically engineering patients' own white blood cells to recognize and attack cancer cells.

4 Sep 2006

Scientists create tumour zapping T cells which knock out cancer

Scientists in the United States have genetically engineered normal immune cells to become specialized fighters and used them to attack cancerous tumours.

31 Aug 2006

Genotoxic bacteria in the digestive tract

Escherichia coli is a commensal bacterium, which lives peacefully in our digestive tract. However, certain strains are pathogenic and are frequently incriminated in a broad spectrum of infections, affecting both farmed animals and humans (diarrhoea, urinary tract infections, food poisoning, septicaemia, neonatal meningitis, etc.).

16 Aug 2006

For the first time, scientists watch neurons change in response to experience

Thanks to a new imaging system, researchers at MIT's Picower Institute for Learning and Memory have gotten an unprecedented look into how genes shape the brain in response to the environment.

6 Aug 2006

How kidneys retain proteins, discard waste

New research may finally settle a decades-old debate about how the kidney keeps valuable blood proteins from harmfully slipping into the urine, a serious health symptom that often precedes kidney failure.

2 Aug 2006

Researchers determine why gene therapy treatment caused leukemia in some X-linked severe combined immunodeficiency patients

Scientists at St. Jude Children's Research Hospital have developed a mouse model of a severe disease of the immune system that helps explain why gene therapy used to treat children with this disease at an institution in Europe caused some of them to develop leukemia.

2 Aug 2006

New genetic model for Parkinson's disease

Researchers at the Karolinska Institute in Sweden are homing in on mechanisms that may explain one set of causes for Parkinson's disease.

1 Aug 2006

Creating your own pandemic virus is not so easy

A team of scientists at the U.S. Centers for Disease Control and Prevention (CDC) have developed a new research method that may help identify the types of genetic changes that would be necessary for the avian influenza virus (H5N1) to be more easily transmitted among people.

1 Aug 2006