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Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

In a new study, researchers performed genomic sequencing of SARS-CoV-2-infected samples and aimed to identify the dominant variant, assess the mutation profile, and determine the sample-to-sequence turnover time.

1 Mar 2022

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

In a new study, researchers used deep transcriptome analysis to examine the coding and non-coding transcriptional landscape of lung cells infected with SARS-CoV-2.

1 Mar 2022

Novel coronavirus identified in Swedish bank voles

Researchers recently discovered a new coronavirus, named Grimso virus, in Swedish bank voles, using samples collected between 2015 and 2017.

1 Mar 2022

US research reveals the role of Heparan Sulfate in obesity

AMSBIO reports how researchers at the Washington University School of Medicine (St. Louis, USA) have used their 10E4 Heparan Sulfate (HS) antibody in pioneering obesity research to quantify the role of HS in the process of intercellular mitochondria transfer to macrophages.

From AMS Biotechnology 1 Mar 2022

Study finds MK-4482 inhibits replication of multiple SARS-CoV-2 variants of concern in Syrian hamster COVID-19 model

Researchers found that an antiviral drug, was effective against SARS-CoV-2 variants, including the recently emerged Omicron variant, in Syrian hamsters.

1 Mar 2022

SARS-CoV-2 protein interactions with viral and host RNAs in authentic virus-infected cells

Researchers investigated protein interactions of SARS-CoV-2 with host and viral RNAs in infected cells.

1 Mar 2022

A study on the evolution of avian coronavirus escape mutants in vitro

A recent study included an in vitro assessment of the effect of antibody titers and vaccine combinations on the emergence of escape mutants of AvCoV.

28 Feb 2022

SARS-CoV-2 monitoring could be improved with use of bacterial metatranscriptomes in wastewater

In a recent research report from the United States, currently available on bioRxiv* preprint server, scientists have shown that bacterial taxonomic and functional profiles can discriminate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) status even without directly detecting viral transcripts – opening the door for entirely novel approaches in wastewater-based epidemiology.

27 Feb 2022

Study determines effectiveness of COVID-19 vaccination against Omicron variant in high-risk indoor settings

A new study estimates vaccine effectiveness against SARS-CoV-2 Omicron variant in indoor entertainment settings in Australia.

27 Feb 2022

Mapping cells to understand vascular disease

In this interview, we speak to Dr. Ethan Winkler and Dr. Tomasz Nowakowski about their latest research which illustrated the interplay between vascular and immune cells that contributes to brain hemorrhage.

25 Feb 2022

Study identifies higher infection rate and lower disease severity during Omicron wave in US

Scientists from the Case Western Reserve University, USA, have recently conducted a study in collaboration with the National Institutes of Health, USA, to investigate the incidence rates and disease severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the United States before and after the emergence of omicron variant.

24 Feb 2022

New stem cell model could help map out the key genomic changes during early development

Researchers from the Babraham Institute have today published their latest work in the journal Cell Stem Cell describing a new subset of human embryonic stem cells that closely resemble the cells present at the genomic 'wake up call' of the 8-cell embryo stage in humans.

24 Feb 2022

Study explores the boosting of SARS-CoV-2 adenovirus vaccine-induced immunity by capsid decoration

Researchers demonstrated that decorating the capsid surface of adenovirus vaccine vectors with a newly discovered protein superglue, DogTag/DogCatcher generates potent SARS-CoV-2-specific humoral and cellular immunity.

24 Feb 2022

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Researchers sought to evaluate the zoonotic potential of BOMV to assess the level of risk to public health.

24 Feb 2022

Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

Researchers developed a hybrid assay incorporating immunological antibody-based viral spike protein capture with molecular nucleic acid amplification by qRT-PCR.

24 Feb 2022

Omicron BA. 2 reinfections can occur shortly following BA.1 infection

Researchers investigated the probability of Omicron BA.2 reinfections following SARS-CoV-2 Omicron BA.1 initial infection by whole genomic sequencing in the period of dominance of these subvariants in Denmark.

24 Feb 2022

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

In a new study, researchers studied SARS-CoV-2 infection on the transcription of mitochondrial oxidative phosphorylation, glycolysis, nutrient sensing, and stress response genes.

24 Feb 2022

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the devastating adult-onset neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

24 Feb 2022

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is hurting our loved ones — even those that walk on four legs. Researchers from the University of Pennsylvania documented the recovery of an 11-year old indoor housecat living in Delaware who first presented to the veterinary hospital after experiencing distressing gastrointestinal symptoms.

23 Feb 2022

Study shows how certain RNA molecules control the repair of damaged DNA in cancer cells

A new study from Karolinska Institutet in Sweden shows how certain RNA molecules control the repair of damaged DNA in cancer cells, a discovery that could eventually give rise to better cancer treatments. The study is published today in the journal Nature Communications.

23 Feb 2022

Genome News and Research

Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

Novel coronavirus identified in Swedish bank voles

US research reveals the role of Heparan Sulfate in obesity

Study finds MK-4482 inhibits replication of multiple SARS-CoV-2 variants of concern in Syrian hamster COVID-19 model

SARS-CoV-2 protein interactions with viral and host RNAs in authentic virus-infected cells

A study on the evolution of avian coronavirus escape mutants in vitro

SARS-CoV-2 monitoring could be improved with use of bacterial metatranscriptomes in wastewater

Study determines effectiveness of COVID-19 vaccination against Omicron variant in high-risk indoor settings

Mapping cells to understand vascular disease

Study identifies higher infection rate and lower disease severity during Omicron wave in US

New stem cell model could help map out the key genomic changes during early development

Study explores the boosting of SARS-CoV-2 adenovirus vaccine-induced immunity by capsid decoration

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

Omicron BA. 2 reinfections can occur shortly following BA.1 infection

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Study shows how certain RNA molecules control the repair of damaged DNA in cancer cells

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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