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Gene variant may help predict people’s response to investigational Alzheimer's therapy

Researchers at the University of California, San Diego School of Medicine have identified a gene variant that may be used to predict people most likely to respond to an investigational therapy under development for Alzheimer's disease (AD).

13 Mar 2015

Scientists simplify chemical synthesis of small molecules using 3D printing technology

Howard Hughes Medical Institute scientists have simplified the chemical synthesis of small molecules, eliminating a major bottleneck that limits the exploration of a class of compounds offering tremendous potential for medicine and technology.

13 Mar 2015

Finding could lead to more effective, less invasive treatment for 'bubble boy' disease

For infants with severe combined immunodeficiency (SCID), something as simple as a common cold or ear infection can be fatal. Born with an incomplete immune system, kids who have SCID--also known as "bubble boy" or "bubble baby" disease--can't fight off even the mildest of germs.

12 Mar 2015

Cannabis abuse affects long-term memory, finds new Northwestern Medicine study

Teens who were heavy marijuana users - smoking it daily for about three years -- had an abnormally shaped hippocampus and performed poorly on long-term memory tasks, reports a new Northwestern Medicine study.

12 Mar 2015

New study explores patient outcomes one year after TAVR procedure

In an analysis of outcomes of about 12,000 patients who underwent transcatheter aortic valve replacement, death rate after one year was nearly one in four; of those alive at 12 months, almost half had not been rehospitalized and approximately 25 percent had only one hospitalization, according to a study in the March 10 issue of JAMA.

12 Mar 2015

Rehospitalizations after severe sepsis may be potentially preventable

In an analysis of about 2,600 hospitalizations for severe sepsis, readmissions within 90 days were common, and approximately 40 percent occurred for diagnoses that could potentially be prevented or treated early to avoid hospitalization, according to a study in the March 10 issue of JAMA.

12 Mar 2015

Fracture prevention project could help save millions

Bone fractures affect millions of people across the UK with 1 in 2 women and 1 in 5 men over the age of 50 suffering from them . The cost of fragility fractures place a substantial economic burden on the health and social care system with the costs of fragility fractures in the region of £2.3bn .

12 Mar 2015

European scientists identify gene linked with certain types of early-onset epilepsy

Certain types of early-onset epilepsy are caused by previously unknown mutations of a potassium channel gene, KCNA2. The mutations disrupt the electrical balance in the brain in two ways. In some patients, the flow of potassium is greatly reduced; while in others, it is raised enormously. Both states can lead to hard-to-treat epileptic seizures. Mental and motor development can come to a stop, or even to regress.

12 Mar 2015

TSRI researchers create picture of whole dynein-dynactin structure

A team led by scientists at The Scripps Research Institute has determined the basic structural organization of a molecular motor that hauls cargoes and performs other critical functions within cells.

12 Mar 2015

Physical activity may protect older people from effects of brain damage

Older people who are physically active may be protecting themselves from the effects of small areas of brain damage that can affect their movement abilities, according to a new study published in the March 11, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Mar 2015

Brazil's first open-access research facility to be established at UNICAMP

Open-access research into drug discovery has arrived in South America, with a ground-breaking collaboration between leading scientists in North America, Europe and Brazil to provide completely free and open research results to the world.

12 Mar 2015

BU study explores birth outcomes for women who receive fertility treatment

Birth outcomes for babies whose mothers used assisted reproductive technology (ART) are better in some cases, and worse in others, than for subfertile women who did not use ART, according to a first-of-its-kind study led by Boston University School of Public Health researchers.

12 Mar 2015

New injectable polymer could strengthen blood clots

Most military battlefield casualties die before ever reaching a surgical hospital. Of those soldiers who might potentially survive, most die from uncontrolled bleeding.

11 Mar 2015

Research findings offer new insights into pathophysiology of PTSD

Researchers at the Veterans Affairs San Diego Healthcare System and University of California, San Diego School of Medicine, with colleagues in New York and the United Kingdom, have identified genetic markers, derived from blood samples that are linked to post-traumatic stress disorder (PTSD). The markers are associated with gene networks that regulate innate immune function and interferon signaling.

11 Mar 2015

Scientists develop mathematical model to digitally map communication between heart cells

A team of scientists led by Johns Hopkins cardiologist and biomedical engineer Hiroshi Ashikaga, M.D., Ph.D., has developed a mathematical model to measure and digitally map the beat-sustaining electrical flow between heart cells.

11 Mar 2015

New evidence links autism risk genes to better cognitive function

Genes linked with a greater risk of developing autism may also be associated with higher intelligence, a study suggests.

11 Mar 2015

New method could lead to improved treatment for NPC patients

Researchers at the University of Birmingham believe that a new method of genetically engineering immune cells could lead to improved treatment of Nasopharyngeal carcinoma (NPC) patients.

11 Mar 2015

Study finds significant links between depression, poor dietary quality and high BMI

In a study published in the Journal of the Academy of Nutrition and Dietetics, researchers from the RAND Corporation report that for people receiving food assistance there are significant links between depression, poor dietary quality, and high body mass index (BMI).

10 Mar 2015

Naturally-occurring protein in the brain can curb binge alcohol drinking

A new study led by University of North Carolina School of Medicine researchers has found that a naturally-occurring protein in the brain can act to suppress binge alcohol drinking, a major public health problem estimated to cost the U.S. more than $170 billion each year.

10 Mar 2015

Use of psychedelic drugs linked to less psychological distress, fewer suicidal thoughts

A history of psychedelic drug use is associated with less psychological distress and fewer suicidal thoughts, planning and attempts, according to new research from Johns Hopkins and the University of Alabama at Birmingham.

10 Mar 2015

X linked News and Research

Gene variant may help predict people’s response to investigational Alzheimer's therapy

Scientists simplify chemical synthesis of small molecules using 3D printing technology

Finding could lead to more effective, less invasive treatment for 'bubble boy' disease

Cannabis abuse affects long-term memory, finds new Northwestern Medicine study

New study explores patient outcomes one year after TAVR procedure

Rehospitalizations after severe sepsis may be potentially preventable

Fracture prevention project could help save millions

European scientists identify gene linked with certain types of early-onset epilepsy

TSRI researchers create picture of whole dynein-dynactin structure

Physical activity may protect older people from effects of brain damage

Brazil's first open-access research facility to be established at UNICAMP

BU study explores birth outcomes for women who receive fertility treatment

New injectable polymer could strengthen blood clots

Research findings offer new insights into pathophysiology of PTSD

Scientists develop mathematical model to digitally map communication between heart cells

New evidence links autism risk genes to better cognitive function

New method could lead to improved treatment for NPC patients

Study finds significant links between depression, poor dietary quality and high BMI

Naturally-occurring protein in the brain can curb binge alcohol drinking

Use of psychedelic drugs linked to less psychological distress, fewer suicidal thoughts

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