Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

New study examines how tumor genome testing helps improve breast cancer treatment

A new study examines how one early example of precision medicine--tumor genome testing--is being used in women with breast cancer to reduce overtreatment and maximize the benefits of chemotherapy.

24 Oct 2016

Rearrangement of collagen linked to poor outcomes in pancreatic cancer patients

A study in the current journal Oncotarget provides the first evidence linking a disturbance of the most common protein in the body with a poor outcome in pancreatic cancer.

21 Oct 2016

Researchers identify proteins in the blood that could improve detection of pancreatic cancer

Pancreatic cancer is one of the most lethal forms of cancer because early stage symptoms are relatively light, often resulting in it being discovered only after spreading to other organs. In order to improve the prognosis of pancreatic cancer, the development of methods for early detection of pancreatic cancer with a blood test is important.

21 Oct 2016

New studies support secretoneurin as new biomarker for cardiovascular disease

Scandinavian cardiovascular diagnostics specialist CardiNor AS today announced two new studies have been published by the group at Akershus University Hospital led by Professor Torbjørn Omland and Associate Professor Helge Røsjø in leading journals that strongly support secretoneurin as a new, important biomarker for cardiovascular disease.

19 Oct 2016

WSU researchers develop portable laboratory on smartphone to detect cancer biomarker

Washington State University researchers have developed a low-cost, portable laboratory on a smartphone that can analyze several samples at once to catch a cancer biomarker, producing lab quality results.

18 Oct 2016

EKF Diagnostics’ novel diabetic biomarker test successfully externally verified

EKF, announces that its Glycated Serum Protein LiquiColor diabetic biomarker test has been verified for use on the Siemens Vista chemistry analyzer.

From EKF Diagnostics 18 Oct 2016

HSS researchers identify new way to quickly diagnose and treat Parsonage-Turner Syndrome

Physicians at Hospital for Special Surgery have been studying patient outcomes of Parsonage-Turner Syndrome (PTS), an uncommon neurological disorder that results in a sudden paralysis of one or more muscles around the shoulder and arm.

18 Oct 2016

How could emerging technologies impact cancer care?

The major innovations in cancer diagnosis, therapy/palliative care and surgical intervention are too numerous to list here. But enormous strides have taken place in stem cell therapy, monoclonal antibody therapy and genetic screening.

17 Oct 2016

Researchers develop MRI-based method that can track progression of genetically mutated gliomas

UT Southwestern Medical Center researchers have developed an MRI-based method that can track the state and progression of a common type of genetically mutated brain cancer.

17 Oct 2016

Mount Sinai awarded $10 million grant to explore cellular, molecular mechanisms of GVHD

Researchers from the Icahn School of Medicine at Mount Sinai have been awarded a $10 million from the National Cancer Institute to explore the cellular and molecular mechanisms of acute graft-versus-host disease (GVHD), a common side effect that occurs after allogeneic bone marrow transplantation (BMT), and to develop novel therapeutic strategies for BMT patients with cancer that begin in the cells of blood-forming tissue or hematologic malignancies.

13 Oct 2016

IPC PAS researchers develop new polymer that may detect early stages of kidney disease

The advanced phase of acute kidney injury can be fatal in even one in two patients. Fortunately, now it will be possible to detect the disease in its initial stages, when treatment is still relatively simple and the prognosis good.

13 Oct 2016

Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models

Results of preclinical studies by investigators at the Medical University of South Carolina reported in the August 2016 issue of Arthritis & Rheumatology demonstrate for the first time that including novel biomarkers in lupus nephritis (LN) prognostic models significantly increases their power to predict therapeutic efficacy.

12 Oct 2016

Study of pan-FGFR inhibitor uses mRNA in tumours to identify responders

The first-in-human dose escalation study of the pan-FGFR (fibroblast growth factor receptor) inhibitor BAY 1163877 in patients with treatment-refractory locally advanced or metastatic solid tumours were reported today at the ESMO 2016 Congress in Copenhagen.

8 Oct 2016

Immunotherapy redefines treatment approach for metastatic bladder cancer patients

Immunotherapy has shown promising results in first and second line treatment of metastatic bladder cancer in two phase II trials presented at the ESMO 2016 Congress in Copenhagen.

8 Oct 2016

New study of Phase II Alzheimer's drug pipeline reveals more ways to combat disease

A new analysis of the Phase II Alzheimer's drug pipeline, conducted by ResearchersAgainstAlzheimer's, revealed 57 new Alzheimer's drugs. According to the analysis, nearly twice as many mechanisms of action are being tested in Phase II than in Phase III clinical trials.

7 Oct 2016

Treatment using PARP inhibitor shrinks tumors in breast cancer patients with BRCA mutations

All 13 newly diagnosed breast cancer patients with BRCA mutations had their tumors shrink significantly when treated with a PARP inhibitor ahead of frontline presurgical chemotherapy in a pilot study at The University of Texas MD Anderson Cancer Center.

5 Oct 2016

Study finds decreased cysteine/cystine ratio could serve as accurate redox biomarker for epilepsy

Approximately 2.9 million people in the United States suffer from epilepsy, according to the CDC.

5 Oct 2016

Researchers identify new strategy to selectively sensitize cancer cells to radiation therapy

Many types of cancer become drug resistant, making them difficult to treat. Researchers with University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to selectively sensitize certain cancer cells to radiation therapy that may improve tumor control and reduce treatment-related side effects.

5 Oct 2016

Scientists discover new method to assess senescence across biomedicine

Scientists have discovered a new way to look for ageing cells across a wide range of biological materials; the new method will boost understanding of cellular development and ageing as well as the causes of diverse diseases.

5 Oct 2016

BBI Solutions launches new range of antibodies for Galectin-3 biomarker

BBI Solutions has announced the launch of a range of antibodies for the biomarker Galectin-3. The antibodies complement BBI’s Galectin-3 antigen, which was also launched earlier this year.

5 Oct 2016

Biomarker News and Research

Further Reading

New study examines how tumor genome testing helps improve breast cancer treatment

Rearrangement of collagen linked to poor outcomes in pancreatic cancer patients

Researchers identify proteins in the blood that could improve detection of pancreatic cancer

New studies support secretoneurin as new biomarker for cardiovascular disease

WSU researchers develop portable laboratory on smartphone to detect cancer biomarker

EKF Diagnostics’ novel diabetic biomarker test successfully externally verified

HSS researchers identify new way to quickly diagnose and treat Parsonage-Turner Syndrome

How could emerging technologies impact cancer care?

Researchers develop MRI-based method that can track progression of genetically mutated gliomas

Mount Sinai awarded $10 million grant to explore cellular, molecular mechanisms of GVHD

IPC PAS researchers develop new polymer that may detect early stages of kidney disease

Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models

Study of pan-FGFR inhibitor uses mRNA in tumours to identify responders

Immunotherapy redefines treatment approach for metastatic bladder cancer patients

New study of Phase II Alzheimer's drug pipeline reveals more ways to combat disease

Treatment using PARP inhibitor shrinks tumors in breast cancer patients with BRCA mutations

Study finds decreased cysteine/cystine ratio could serve as accurate redox biomarker for epilepsy

Researchers identify new strategy to selectively sensitize cancer cells to radiation therapy

Scientists discover new method to assess senescence across biomedicine

BBI Solutions launches new range of antibodies for Galectin-3 biomarker

Event guide: 16th Clinical Biomarkers & CDx Summit Europe eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo