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Scientists reveal biochemical pathway responsible for manufacturing glycoalkaloids

In 1924, Science magazine reported on a fatal case of potato poisoning: James B. Matheney of Vandalia, Illinois, had gathered about one and a half bushels of tubers, which had turned green due to sunlight exposure.

1 Aug 2013

New approach could provide alternative treatment for chemotherapy-resistant breast cancer

A new way to target a breast cancer cells' appetite for over-indulging in sugar, that could provide an alternative treatment for chemotherapy resistant breast cancer, is being developed by Breast Cancer Campaign scientists at the University of Southampton.

1 Aug 2013

Junk-food diet during pregnancy may change development of opioid pathway in baby's brain

Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, shows that eating a junk-food diet during pregnancy changes the development of the opioid signalling pathway in the baby's brain and permanently alters the way this system operates after birth.

30 Jul 2013

Graduate student receives NIH fellowship of more than $90,000 to study e-cigarette use

Ever since e-cigarettes hit the market in 2004, they have been advertised as an aid for cigarette smoking cessation. The aerosols produced by e-cigarettes, however, have yet to be screened for potential health risks.

30 Jul 2013

Researchers discover solution to long-standing medical mystery in Huntington's disease

Researchers at McMaster University have discovered a solution to a long-standing medical mystery in Huntington's disease (HD). HD is a brain disease that can affect 1 in about 7,000 people in mid-life, causing an increasing loss of brain cells at the centre of the brain.

30 Jul 2013

Researchers find how brain cells communicate with each other in different voice tones

Brain cells talk to each other in a variety of tones. Sometimes they speak loudly but other times struggle to be heard. For many years scientists have asked why and how brain cells change tones so frequently. Today National Institutes of Health researchers showed that brief bursts of chemical energy coming from rapidly moving power plants, called mitochondria, may tune brain cell communication.

26 Jul 2013

NeoGenomics launches clinical molecular tests for comprehensive profiling of MDS

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today that it has validated and launched a number of clinical molecular tests for the comprehensive profiling of myelodysplastic syndrome.

25 Jul 2013

Perfluoroalkyl substances are crossing blood brain barrier of polar bears

PerFluoroAlkyl Substances (PFASs) and precursor compounds have been used in a wide variety of commercial and industrial products over the past six decades. Applications include water and oil repellent coatings, e.g. for textiles, paper products, carpets and food packaging, pharmaceuticals and surfactants in cleaning products and fire-fighting foams.

25 Jul 2013

Researchers discover mechanism that prevents immune system from spinning out of control

A team led by a University of Arizona researcher has discovered a previously unknown mechanism that prevents the immune system from going into overdrive, shedding light not only on how our body controls its response to pathogens but on conditions such as autoimmune diseases, allergies and chronic inflammation as well.

24 Jul 2013

Researchers develop reliable way to use finger-stick blood sample to detect fibromyalgia syndrome

Researchers have developed a reliable way to use a finger-stick blood sample to detect fibromyalgia syndrome, a complicated pain disorder that often is difficult to diagnose.

24 Jul 2013

Discovery may help explain how anti-inflammatory steroid drugs work

A gene long presumed dead comes to life under the full moon of inflammation, Stanford University School of Medicine scientists have found.

23 Jul 2013

Researchers use peels of apples and tomatoes to purify water

One of the most crucial problems affecting the world today is the scarcity of potable water. In a bid to make clean water available at low cost, Mr Ramakrishna Mallampati, a PhD candidate at the National University of Singapore, experimented with water treatment techniques using materials that are easily available, and came up with novel ways to purify water using the peels of apples and tomatoes.

22 Jul 2013

Weeds derived from crop plant pose special challenges for modern farming

The evolutionary biologist Stephen Jay Gould once asked whether the living world would be different "if the tape were played twice." If there were a duplicate Earth evolving quietly beside ours, would we observe the emergence of creatures like ourselves and of plants and anaimals familiar to us, or would the cast of characters be entirely different?

22 Jul 2013

Researchers discover new functions for PTPN22 gene linked with autoimmune disease

Researchers at the University of Minnesota have identified infection-fighting and inflammation-suppressing functions for a gene associated with human autoimmune disease.

20 Jul 2013

Metabolomics tools predict who can benefit from treatment with certain antidepressants

Duke Medicine researchers have identified biochemical changes in people taking antidepressants - but only in those whose depression improves. These changes occur in a neurotransmitter pathway that is connected to the pineal gland, the part of the endocrine system that controls the sleep cycle, suggesting an added link between sleep, depression and treatment outcomes.

19 Jul 2013

HemoShear announces milestone in development of predictive drug safety systems

HemoShear, LLC, a leading developer of human-relevant systems for drug development and discovery, today announced an important milestone in the development of systems that predict safety of new drugs and chemicals.

19 Jul 2013

Scientists develop iKnife that helps surgeons identify cancerous tissues

Scientists have developed an "intelligent knife" that can tell surgeons immediately whether the tissue they are cutting is cancerous or not.

18 Jul 2013

Exposure to PFC may increase risk of mild hypothyroidism in women

Exposure to perfluorinated chemicals is linked to changes in thyroid function and may raise the risk of mild hypothyroidism in women, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

18 Jul 2013

Modified forms of bisphenol A found to alter hormone signaling in new, disturbing ways

For years, scientists have been worried about bisphenol A. The chemical is known as an "endocrine disruptor," a substance that interferes with the body's hormone signaling system, and it's found in everything from plastic drink bottles to the linings of food and drink cans to the thermal paper used for cash register receipts - not to mention the urine of 92.6 percent of Americans over the age of six.

18 Jul 2013

Long-term cannabis use, dopamine and motivation: an interview with Dr Michael Bloomfield, Department of Medicine at Imperial

We classified ‘long-term’ cannabis use as being regular, at least weekly, cannabis use for over 12 months. This is the period of time that’s used in the DSM-IV psychiatric diagnostic manual to classify substance use disorders. In our study the average duration of at least weekly use was just over four and a half years.

17 Jul 2013

Chemicals News and Research

Scientists reveal biochemical pathway responsible for manufacturing glycoalkaloids

New approach could provide alternative treatment for chemotherapy-resistant breast cancer

Junk-food diet during pregnancy may change development of opioid pathway in baby's brain

Graduate student receives NIH fellowship of more than $90,000 to study e-cigarette use

Researchers discover solution to long-standing medical mystery in Huntington's disease

Researchers find how brain cells communicate with each other in different voice tones

NeoGenomics launches clinical molecular tests for comprehensive profiling of MDS

Perfluoroalkyl substances are crossing blood brain barrier of polar bears

Researchers discover mechanism that prevents immune system from spinning out of control

Researchers develop reliable way to use finger-stick blood sample to detect fibromyalgia syndrome

Discovery may help explain how anti-inflammatory steroid drugs work

Researchers use peels of apples and tomatoes to purify water

Weeds derived from crop plant pose special challenges for modern farming

Researchers discover new functions for PTPN22 gene linked with autoimmune disease

Metabolomics tools predict who can benefit from treatment with certain antidepressants

HemoShear announces milestone in development of predictive drug safety systems

Scientists develop iKnife that helps surgeons identify cancerous tissues

Exposure to PFC may increase risk of mild hypothyroidism in women

Modified forms of bisphenol A found to alter hormone signaling in new, disturbing ways

Long-term cannabis use, dopamine and motivation: an interview with Dr Michael Bloomfield, Department of Medicine at Imperial

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