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Scientists define key underlying process implicated in multiple sclerosis

Scientists at the Gladstone Institutes have defined for the first time a key underlying process implicated in multiple sclerosis (MS)-a disease that causes progressive and irreversible damage to nerve cells in the brain and spinal cord. This discovery offers new hope for the millions who suffer from this debilitating disease for which there is no cure.

30 Nov 2012

Reduction in myelin production may also play a role in development of mental illness

Reduced production of myelin, a type of protective nerve fiber that is lost in diseases like multiple sclerosis, may also play a role in the development of mental illness, according to researchers at the Graduate School of Biomedical Sciences at Mount Sinai School of Medicine. The study is published in the journal Nature Neuroscience.

29 Nov 2012

Musical Moments for MS honors Kessler Foundation expert with Medical Excellence Award

John DeLuca, PhD, Vice President for Research and Training at Kessler Foundation, was named this year's recipient of the Medical Excellence Award by Musical Moments for MS. Dr. DeLuca will be honored at the 10th Anniversary of Musical Moments for MS on Tuesday, December 11 at NJPAC in Newark, NJ.

29 Nov 2012

IL17RC-mediated immune responses can be crucial in causing AMD

Changes in how genes in the immune system function may result in age-related macular degeneration (AMD), the leading cause of visual impairment in older adults, based on preliminary research conducted by National Institutes of Health (NIH) investigators.

29 Nov 2012

Biomarker for ALS progression shows promise

Levels of a neurofilament subunit in cerebral spinal fluid, serum, or plasma may predict disease progression in individuals with amyotrophic lateral sclerosis, report researchers.

28 Nov 2012

The Neuro clinician-scientists to further research on HIV/AIDS, Parkinson's

Clinician-scientists take a unique, integrated approach that is essential to advancing science and medicine. Problems encountered in the clinic inspire research and new findings from the labs are directly applied to patients' needs.

28 Nov 2012

Researchers aim to improve feeling of 'walking on marbles' for arthritis patients

Researchers at the University of Southampton are to undertake a new stage of a study aimed at improving the health and mobility of those suffering from the common complaint of 'walking on marbles' associated with Rheumatoid Arthritis (RA) in the feet.

28 Nov 2012

High-resolution real-time images show how nerves may be damaged during earliest stages of MS

High-resolution real-time images show in mice how nerves may be damaged during the earliest stages of multiple sclerosis. The results suggest that the critical step happens when fibrinogen, a blood-clotting protein, leaks into the central nervous system and activates immune cells called microglia.

28 Nov 2012

Specific combination of two pharmaceutical substances show promise against multiple sclerosis

A new substance class for the treatment of multiple sclerosis and other neurodegenerative diseases now promises increased efficacy paired with fewer side effects. To achieve this, a team of scientists under the leadership of Prof. Gunter Fischer and Dr. Frank Striggow have combined two already approved pharmaceutical substances with each other using a chemical linker structure.

27 Nov 2012

New way to protect neurons that express mutant huntingtin proteins

By using a model, researchers at the University of Montreal have identified and "switched off" a chemical chain that causes neurodegenerative diseases such as Huntington's disease, amyotrophic lateral sclerosis and dementia. The findings could one day be of particular therapeutic benefit to Huntington's disease patients. "We've identified a new way to protect neurons that express mutant huntingtin proteins," explained Dr. Alex Parker of the University of Montreal's Department of Pathology and Cell Biology and its affiliated CRCHUM Research Centre.

27 Nov 2012

Apitope announces completion of recruitment in ATX-MS-1467 Phase I trial for MS

Apitope, the European drug discovery and development company focused on treating the underlying cause of autoimmune diseases, today announced completion of recruitment into its second Phase I clinical trial of ATX-MS-1467 in patients with multiple sclerosis (MS).

26 Nov 2012

Lymphopenia driven diseases and the orphan drug industry: an interview with Damian Marron, CEO of Cytheris

Lymphopenia is when you lack the T cells of your immune system. T cells are very important for controlling infection. Probably the most known cause of lymphopenia is HIV.

23 Nov 2012

Australian TGA approves Genzyme’s AUBAGIO to treat relapsing forms of multiple sclerosis

Genzyme, a Sanofi company, announced today that the Australian Therapeutic Goods Administration (TGA) has approved AUBAGIO (teriflunomide) 14 mg as a new once-daily, oral treatment indicated for patients with relapsing forms of multiple sclerosis (MS).

21 Nov 2012

Electrophysiology: an interview with Dr Kaylene Young

Bioelectricity is an essential part of our make-up. All cells in our body communicate by electrical activity. If an electrical charge is applied to one of our muscles it will interpret that electrical activity as a signal telling it to contract.

21 Nov 2012

Simple, accurate testing protocol to determine driving fitness in individuals with MS

A simple, accurate testing protocol to determine driving fitness in individuals with multiple sclerosis is the aim of a three-year study at Georgia Health Sciences University.

21 Nov 2012

Novel test reveals rate of progression of amyotrophic lateral sclerosis in patients

A novel test that measures proteins from nerve damage that are deposited in blood and spinal fluid reveals the rate of progression of amyotrophic lateral sclerosis (ALS) in patients, according to researchers from Mayo Clinic's campus in Florida, Emory University and the University of Florida.

21 Nov 2012

Study: 2-PMPA improves cognition in mice with MS

Johns Hopkins researchers report the successful use of a form of MRI to identify what appears to be a key biochemical marker for cognitive impairment in the brains of people with multiple sclerosis (MS). In follow-up experiments on mice with a rodent form of MS, researchers were able to use an experimental compound to manipulate that same marker and dramatically improve learning and memory.

21 Nov 2012

Sclerosis News and Research

Scientists define key underlying process implicated in multiple sclerosis

Reduction in myelin production may also play a role in development of mental illness

Musical Moments for MS honors Kessler Foundation expert with Medical Excellence Award

IL17RC-mediated immune responses can be crucial in causing AMD

Biomarker for ALS progression shows promise

The Neuro clinician-scientists to further research on HIV/AIDS, Parkinson's

Researchers aim to improve feeling of 'walking on marbles' for arthritis patients

High-resolution real-time images show how nerves may be damaged during earliest stages of MS

Specific combination of two pharmaceutical substances show promise against multiple sclerosis

New way to protect neurons that express mutant huntingtin proteins

Apitope announces completion of recruitment in ATX-MS-1467 Phase I trial for MS

Lymphopenia driven diseases and the orphan drug industry: an interview with Damian Marron, CEO of Cytheris

Australian TGA approves Genzyme’s AUBAGIO to treat relapsing forms of multiple sclerosis

Electrophysiology: an interview with Dr Kaylene Young

Simple, accurate testing protocol to determine driving fitness in individuals with MS

Novel test reveals rate of progression of amyotrophic lateral sclerosis in patients

Study: 2-PMPA improves cognition in mice with MS

High blood levels of vitamin D may protect mothers more than babies against MS

Small non-coding RNA715 plays an important role in regulating myelin formation in the CNS

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Improving healthcare sustainability through carbon data

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Bringing real-time analytics to downstream bioprocess monitoring

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