Infectious Diseases News and Research

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Sinopharm's candidate SARS-CoV-2 vaccine BBIBP-CorV shows promise in clinical trials

Researchers in China have conducted a phase 1/2 trial demonstrating the safety, tolerability, and immunogenicity of a candidate vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

18 Oct 2020

NIH launches adaptive Phase 3 clinical trial to test immune modulator drugs in COVID-19 patients

The National Institutes of Health has launched an adaptive Phase 3 clinical trial to evaluate the safety and efficacy of three immune modulator drugs in hospitalized adults with COVID-19.

16 Oct 2020

Novel method can predict influenza epidemics

Researchers at Linköping University, Sweden, have developed a unique method to predict influenza epidemics by combining several sources of data.

16 Oct 2020

Patients with soft-tissue cancer show rapid and complete response to novel combination of immunotherapy

A patient with end-stage and rapidly progressing soft-tissue cancer whose tumor did not respond to standard treatment, had a "rapid and complete response" to a novel combination of immunotherapy, according to new research published by a team of scientists from John Theurer Cancer Center at Hackensack University Medical Center and the Georgetown Lombardi Comprehensive Cancer Center, both of whom are part of the Georgetown Lombardi Comprehensive Cancer Center Consortium.

16 Oct 2020

Scientists discover a novel antiviral strategy for treating COVID-19

A research team led by Professor Hongzhe SUN, Norman & Cecilia Yip Professor in Bioinorganic Chemistry, Department of Chemistry, Faculty of Science, and Professor Kwok Yung YUEN, Henry Fok Professor in Infectious Diseases, Department of Microbiology, Li Ka Shing Faculty of Medicine of the University of Hong Kong (HKU), has discovered a novel antiviral strategy for treatment of COVID-19.

16 Oct 2020

NFID issues new report detailing risks of co-infection with flu and COVID-19 in vulnerable adults

The National Foundation for Infectious Diseases (NFID) issued a new Call to Action report detailing the risks of co-infection with influenza (flu) and COVID-19 in adults with chronic health conditions, and the importance of flu vaccination during the 2020-2021 season.

16 Oct 2020

High-titer convalescent plasma reduced COVID-19 symptom severity in green monkeys

As scientists scramble to find effective vaccines and antivirals for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a recent study published on the preprint server bioRxiv in October 2020 reports that the use of convalescent plasma to treat COVID-19 disease early in the course of the illness may be among the best available strategies at present.

16 Oct 2020

Researchers identify potential drugs that could be repurposed as pan-coronavirus treatments

A large international consortium of almost 200 researchers from 14 leading institutions in six countries has studied three different coronaviruses - SARS-CoV-1, SARS-CoV-2, and MERS-CoV - with the aim of finding vulnerabilities shared by these three pathogens.

15 Oct 2020

Cloud-based tool can rapidly detect and track emerging pathogens

Published today in the journal GigaScience is a new open source, cloud-based tool called IDseq that makes it possible to rapidly detect, identify, and track emerging pathogens such as SARS-CoV-2.

15 Oct 2020

GIV protein involved in the immune system could form basis for novel therapeutics

The immune response to infections is a delicate balance. We need just enough action to clear away the offending bacteria or viruses, but not so much that our own bodies suffer collateral damage.

15 Oct 2020

Capillary blood microsampling could prove a breakthrough in SARS-CoV-2 serosurveillance

As COVID-19 seems to be making a comeback in many areas of the world, including Japan, a new study published on the preprint server medRxiv in October 2020 shows the relevance of microsamples of blood in serosurveillance of this disease.

15 Oct 2020

Researchers receive $1.35 million grant to reduce impact of substance abuse in Appalachia

McDowell County--in the southern coalfields of West Virginia--is the second-most at-risk in the nation for an HIV outbreak related to drug injection. Neighboring Wyoming and Mercer Counties follow close behind. All three have some of the highest rates of acute hepatitis B and hepatitis C in the United States.

14 Oct 2020

FDA approves Regeneron antibody drug as first treatment for Ebola virus

Today, the U.S. Food and Drug Administration approved Inmazeb (atoltivimab, maftivimab, and odesivimab-ebgn), a mixture of three monoclonal antibodies, as the first FDA-approved treatment for Zaire ebolavirus (Ebola virus) infection in adult and pediatric patients.

14 Oct 2020

Army researchers team up to test alternative ways to measure COVID-19 antibody levels

Researchers with the U.S. Army Futures Command are part of a team that tested alternative ways to measure COVID-19 antibody levels, resulting in a process that is faster, easier and less expensive to use on a large scale.

14 Oct 2020

Researchers receive $11 million grant to study factors involved in multi-drug resistant infections

A study aimed at better understanding why some critically ill patients develop multidrug-resistant infections is underway by researchers at The University of Texas Health Science Center at Houston.

14 Oct 2020

Blood profile could help identify COVID-19 patients at greatest risk of deterioration

Southampton researchers have identified a blood profile that could help identify COVID-19 patients at greatest risk of deterioration and direct them towards trials of specific treatments that could modify their immune systems' responses.

14 Oct 2020

Scientists discover new method to retrieve lost single-cell RNA-sequencing information

Sequencing RNA from individual cells can reveal a great deal of information about what those cells are doing in the body. MIT researchers have now greatly boosted the amount of information gleaned from each of those cells, by modifying the commonly used Seq-Well technique.

14 Oct 2020

NIH launches new study to streamline COVID-19 treatments for larger clinical studies

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, today launched a study designed to determine whether certain approved therapies or investigational drugs in late-stage clinical development show promise against COVID-19 and merit advancement into larger clinical trials.

14 Oct 2020

New clinical trial to test safety and efficacy of antibody cocktail against COVID-19

In a new clinical trial, UC Davis Health will test the effectiveness and safety of REGN-COV2, the monoclonal antibody cocktail, in preventing COVID-19 in adults living with infected patients.

14 Oct 2020

Researchers create multi-functional nano-vaccine to prevent toxoplasmosis

Fighting clever parasites requires smart vaccines that can trigger critical immune responses. A University of Chicago-based research team has found a novel way to do that.

14 Oct 2020

Infectious Diseases News and Research

Sinopharm's candidate SARS-CoV-2 vaccine BBIBP-CorV shows promise in clinical trials

NIH launches adaptive Phase 3 clinical trial to test immune modulator drugs in COVID-19 patients

Novel method can predict influenza epidemics

Patients with soft-tissue cancer show rapid and complete response to novel combination of immunotherapy

Scientists discover a novel antiviral strategy for treating COVID-19

NFID issues new report detailing risks of co-infection with flu and COVID-19 in vulnerable adults

High-titer convalescent plasma reduced COVID-19 symptom severity in green monkeys

Researchers identify potential drugs that could be repurposed as pan-coronavirus treatments

Cloud-based tool can rapidly detect and track emerging pathogens

GIV protein involved in the immune system could form basis for novel therapeutics

Capillary blood microsampling could prove a breakthrough in SARS-CoV-2 serosurveillance

Researchers receive $1.35 million grant to reduce impact of substance abuse in Appalachia

FDA approves Regeneron antibody drug as first treatment for Ebola virus

Army researchers team up to test alternative ways to measure COVID-19 antibody levels

Researchers receive $11 million grant to study factors involved in multi-drug resistant infections

Blood profile could help identify COVID-19 patients at greatest risk of deterioration

Scientists discover new method to retrieve lost single-cell RNA-sequencing information

NIH launches new study to streamline COVID-19 treatments for larger clinical studies

New clinical trial to test safety and efficacy of antibody cocktail against COVID-19

Researchers create multi-functional nano-vaccine to prevent toxoplasmosis

NGS for Infectious Disease Surveillance eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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