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Study: Injectable 3D vaccines could help prevent cancer, infectious disease

One of the reasons cancer is so deadly is that it can evade attack from the body's immune system, which allows tumors to flourish and spread. Scientists can try to induce the immune system, known as immunotherapy, to go into attack mode to fight cancer and to build long lasting immune resistance to cancer cells.

9 Dec 2014

New trial shows efficacy of PrimiCell product on muscle repair

BioAdaptives, Inc. announced results of the recently completed in vivo trial showing the efficacy of its PrimiCell product on muscle repair.

8 Dec 2014

Comb-shaped polymers efficiently protect proteins in vivo

An enzyme that usually triggers strong allergic reactions now circulates in the veins of a group of mice without alerting the immune system. As INRS Énergie Matériaux Télécommunications Research Centre Professor Marc A. Gauthier explains in an article published in the journal Nature Communications, a polymer was used to camouflage the enzyme before it was injected into the rodents. This was achieved by coating the enzyme to avoid an immune response in a manner that does not compromise its activity.

6 Dec 2014

New light-triggered strategy can provide accurate control over aptamer-based therapeutics

While aptamers—single-stranded nucleic acids—offer promise as drug-delivery tools for cancer treatment, it has proven difficult to get them to tumor cells at therapeutic levels.

4 Dec 2014

Alizé Pharma obtains exclusive worldwide rights to develop new therapy for bone diseases

Alizé Pharma III SAS, an Alizé Pharma group company specialized in the development of biopharmaceuticals to treat metabolic disorders and rare diseases, today announces that it has acquired exclusive worldwide rights to develop and commercialize a new family of peptides with bone anabolic properties.

4 Dec 2014

Faster and more accurate method for testing new cancer drugs

Finding faster and more accurate ways to test new cancer drugs is always a priority for cancer researchers.

2 Dec 2014

Physiologists use new method to identify two odorant receptors in live mice

A group of physiologists led by University of Kentucky's Tim McClintock have identified the receptors activated by two odors using a new method that tracks responses to smells in live mice.

2 Dec 2014

Novartis to highlight advances in blood, breast cancer research at ASH and SABCS 2014

Novartis will highlight more than 250 abstracts demonstrating advances in blood and breast cancer research at the upcoming American Society of Hematology (ASH) annual meeting December 6-9, and CTRC-AACR San Antonio Breast Cancer Symposium (SABCS) December 9-13.

2 Dec 2014

VE-PTP potential treatment target for retinal and choroidal vascular diseases

Targeting vascular endothelial-protein tyrosine phosphatase, which negatively regulates TIE2 activation, could help to stabilise retinal and choroidal blood vessels, researchers report.

1 Dec 2014

New active substance effectively combats Philadelphia chromosome-positive leukaemia

Haematologists from Goethe University Frankfurt, working with a Russian pharmaceutical company, have developed a new active substance that effectively combats the most aggressive forms of Philadelphia chromosome-positive leukaemia.

29 Nov 2014

Researchers use EHRs to uncover hidden drug benefits

With research and development costs for many drugs reaching well into the billions, pharmaceutical companies want more than ever to determine whether their drugs already at market have any hidden therapeutic benefits that could warrant putting additional indications on the label and increase production.

27 Nov 2014

$Scientists use TPF-SHG microscopy to study effects of micro-ablative fractional laser resurfacing$

Scientists use TPF-SHG microscopy to study effects of micro-ablative fractional laser resurfacing

Many people in the Western World consider it as a social need to hide the effects of aging. For this purpose, different cutaneous rejuvenation treatments have been developed, including a laser-based technique, known as laser resurfacing.

20 Nov 2014

WSU researchers working on new system to reduce negative effects of cancer drugs

Wichita State University researchers are working on a new system that could decrease the negative effects of cancer drugs on patients.

19 Nov 2014

Type 3 interferons and T helper 2 cells: an interview with Grant Gallagher, Managing Director, HUMIGEN

The type 3 interferons - usually called the “lambda” interferons, or “IFNL” - are the most recently identified IFNs. We (myself and Sergei Kotenko) originally identified the receptor and then the three ligands (IFNL1,2,3; very recently a fourth, IFNL4, was discovered); the key paper was published in 2003.

18 Nov 2014

Chaetocin synergistic with TKIs against CML cells

Chaetocin, a mycotoxin that increases oxidative stress, can complement the activity of tyrosine kinase inhibitors in chronic myeloid leukaemia by overcoming innate resistance mediated by secreted bone marrow stromal cytokines and growth factors, researchers report.

14 Nov 2014

Load bearing, biodegradable implants can reduce the number of second surgeries

No other joint in the human body is as highly mobile as is the shoulder. However, it is also very sensitive and prone to injury, with athletes being particularly affected.

14 Nov 2014

Bevacizumab–erlotinib combined efficacy may depend on VEGF level

Bevacizumab may enhance the antitumour activity of erlotinib by increasing the intratumoural concentration of erlotinib in some non-small-cell lung cancers expressing high levels of vascular endothelial growth factor, Japanese researchers report.

13 Nov 2014

LaVision BioTec introduce new products for their UltraMicroscope and TriM Scope microscopy products at Neuroscience 2014

LaVision BioTec, developers of advanced microscopy solutions for the life sciences, announce they will introduce new products for their UltraMicroscope and TriM Scope microscopy products at the 2014 annual meeting of the Society for Neuroscience (SfN).

13 Nov 2014

Unique immunochemotherapy approach to treating pancreatic cancer

VCU Massey Cancer Center and VCU Institute of Molecular Medicine researchers discovered a unique approach to treating pancreatic cancer that may be potentially safe and effective. The treatment method involves immunochemotherapy - a combination of chemotherapy and immunotherapy, which uses the patient's own immune system to help fight against disease.

13 Nov 2014

Researchers create microtube platform to analyze neuron growth

Tiny, thin microtubes could provide a scaffold for neuron cultures to grow so that researchers can study neural networks, their growth and repair, yielding insights into treatment for degenerative neurological conditions or restoring nerve connections after injury.

12 Nov 2014

in vivo News and Research

Study: Injectable 3D vaccines could help prevent cancer, infectious disease

New trial shows efficacy of PrimiCell product on muscle repair

Comb-shaped polymers efficiently protect proteins in vivo

New light-triggered strategy can provide accurate control over aptamer-based therapeutics

Alizé Pharma obtains exclusive worldwide rights to develop new therapy for bone diseases

Faster and more accurate method for testing new cancer drugs

Physiologists use new method to identify two odorant receptors in live mice

Novartis to highlight advances in blood, breast cancer research at ASH and SABCS 2014

VE-PTP potential treatment target for retinal and choroidal vascular diseases

New active substance effectively combats Philadelphia chromosome-positive leukaemia

Researchers use EHRs to uncover hidden drug benefits

Scientists use TPF-SHG microscopy to study effects of micro-ablative fractional laser resurfacing

WSU researchers working on new system to reduce negative effects of cancer drugs

Type 3 interferons and T helper 2 cells: an interview with Grant Gallagher, Managing Director, HUMIGEN

Chaetocin synergistic with TKIs against CML cells

Load bearing, biodegradable implants can reduce the number of second surgeries

Bevacizumab–erlotinib combined efficacy may depend on VEGF level

LaVision BioTec introduce new products for their UltraMicroscope and TriM Scope microscopy products at Neuroscience 2014

Unique immunochemotherapy approach to treating pancreatic cancer

Researchers create microtube platform to analyze neuron growth

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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