Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

New research could lead to improved treatment for depression

SCIENTISTS at the University of Huddersfield led by Dr Patrick McHugh have embarked on a project that could lead to a more effective treatment for depression.

10 Aug 2016

Researchers uncover how GWAS-implicated gene affects HDL-cholesterol levels

Researchers have uncovered how genes identified from genome-wide association studies (GWAS) affect high-density lipoprotein cholesterol (HDL-C), a biomarker of cardiovascular disease, after comparing several animal models with human patient data.

10 Aug 2016

ISU researchers discover protein that appears to predict memory loss, brain atrophy in Alzheimer's patients

Iowa State University researchers have identified a protein essential for building memories that appears to predict the progression of memory loss and brain atrophy in Alzheimer's patients.

4 Aug 2016

New biochip test helps identify individuals at increased risk of Alzheimer's disease

Researchers today unveiled results from a new blood test to help identify which patients are at an elevated risk of Alzheimer's disease.

3 Aug 2016

Rice University bioengineer receives NIH grant to study use of AAV-based therapy to combat ovarian cancer

Rice University bioengineer Junghae Suh has been awarded a prestigious R01 grant by the National Institutes of Health to research the use of viral gene therapy to fight ovarian cancer.

3 Aug 2016

Oxford researchers developing new automated system for easier, cheaper diagnosis of pneumonia

Oxford researchers are developing a tool to make it much easier and cheaper to diagnose pneumonia -- the number one killer of children under 5. Their latest research is published in Journal of the Royal Society Interface.

3 Aug 2016

Study creates comprehensive list of blood biomarkers relevant for early detection of cancer

Researchers have identified 788 biomarkers in blood that could be used to develop an early stage cancer screening test for the general population.

1 Aug 2016

Scientists use Regeneration Intelligence to assess perturbation status of many signaling pathways

Insilico Medicine, Inc in collaboration with scientists from Atlas Regeneration, Inc, Vision Genomics, Inc and Howard University published two research papers on fibrosis in the lung and liver and fibrotic signatures in glaucoma.

30 Jul 2016

Roche announces FDA approval of new VENTANA PD-L1 assay

Roche today announced approval of the VENTANA PD-L1 (SP142) Assay by the US Food and Drug Administration as a complementary diagnostic to provide PD-L1 status on patients who are considering treatment with the FDA approved Roche immunotherapy TECENTRIQ™ (atezolizumab) for metastatic urothelial cancer (mUC).

30 Jul 2016

Research could help clinicians identify patients who may benefit from targeted therapy for liver cancer

New research from Roswell Park Cancer Institute offers clinicians treating patients with advanced liver cancer a way of determining which patients may benefit most from the targeted therapy sorafenib.

29 Jul 2016

CD4/CD8 ratio biomarker could help identify HIV-infected individuals at risk for heart disease

The ratio of CD4 to CD8 T cells in the blood-a marker of immune system health and associated with mortality risk in the general population-is an independent predictor of coronary heart disease in HIV-infected patients, according to a new study published in AIDS Research and Human Retroviruses, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

29 Jul 2016

Resveratrol may be clinically beneficial to people with Alzheimer's disease

Resveratrol, given to Alzheimer's patients, appears to restore the integrity of the blood-brain barrier, reducing the ability of harmful immune molecules secreted by immune cells to infiltrate from the body into brain tissues, say researchers at Georgetown University Medical Center.

28 Jul 2016

Levels of peptide hormone adropin linked to carbohydrate intake

In research featured in the August edition of Obesity, Saint Louis University investigator Andrew Butler, Ph.D., and his team report that levels of the peptide hormone adropin vary based on carbohydrate consumption and appear to be linked to lipid metabolism.

27 Jul 2016

Waterloo researchers unveil new screening tool and data at 2016 AAIC

Two studies involving University of Waterloo researchers presented this week at the 2016 Alzheimer's Association International Conference (AAIC) in Toronto highlight a new diagnostic tool that can identify Alzheimer's disease long before the onset of symptoms as well as the increasing prevalence of Alzheimer's disease in Ontario.

27 Jul 2016

Liquid biopsies hold potential for detecting NSCLC EGFR mutations, predicting cancer recurrence

Three manuscripts published in the recent issue of the Journal of Thoracic Oncology, the official journal of the International Association for the Study of Lung Cancer, explored the versatility of liquid biopsies by identifying EGFR mutations using circulating tumor DNA (ctDNA) in urine and plasma and examining circulating tumor cells (CTCs) in plasma to predict the risk of lung cancer recurrence after surgical resection.

26 Jul 2016

Menopause and insomnia could make women age faster

Two UCLA studies reveal that menopause--and the insomnia that often accompanies it -- make women age faster.

26 Jul 2016

Identifying new pathway of EZH2 gene may lead to targeted therapies for aggressive breast cancer

Scientists from A*STAR's Genome Institute of Singapore and the Cancer Science Institute of Singapore at the National University of Singapore came together to understand how EZH2, a cancer-promoting gene which is known to be involved in many types of cancers, is activated in breast cancer and lymphomas.

19 Jul 2016

Researchers detect high levels of arsenic, chromium and kidney injury biomarker in children of Mexico

Water supply contamination has become a global issue, affecting communities in both the United States and around the world.

19 Jul 2016

JAD announces recipient of 2016 Alzheimer Award

The Journal of Alzheimer's Disease is pleased to announce that Mark W. Bondi, PhD, ABPP/CN, Professor of Psychiatry at UC San Diego and Director of the Neuropsychological Assessment Unit at the VA San Diego Healthcare System, has been chosen as the recipient of the 2016 Alzheimer Award presented by the journal in recognition of his outstanding work on the development of a novel and promising method of staging preclinical Alzheimer's disease (AD) based on number of abnormal biomarkers that is predictive of progression to mild cognitive impairment (MCI) and AD.

15 Jul 2016

Expanding the potential of existing cancer therapies: an interview with Dr Mark Rutstein

Cancer remains a leading cause of death worldwide, and the global cancer burden is expected to increase by 70 percent over the next two decades.

14 Jul 2016

Biomarker News and Research

Further Reading

New research could lead to improved treatment for depression

Researchers uncover how GWAS-implicated gene affects HDL-cholesterol levels

ISU researchers discover protein that appears to predict memory loss, brain atrophy in Alzheimer's patients

New biochip test helps identify individuals at increased risk of Alzheimer's disease

Rice University bioengineer receives NIH grant to study use of AAV-based therapy to combat ovarian cancer

Oxford researchers developing new automated system for easier, cheaper diagnosis of pneumonia

Study creates comprehensive list of blood biomarkers relevant for early detection of cancer

Scientists use Regeneration Intelligence to assess perturbation status of many signaling pathways

Roche announces FDA approval of new VENTANA PD-L1 assay

Research could help clinicians identify patients who may benefit from targeted therapy for liver cancer

CD4/CD8 ratio biomarker could help identify HIV-infected individuals at risk for heart disease

Resveratrol may be clinically beneficial to people with Alzheimer's disease

Levels of peptide hormone adropin linked to carbohydrate intake

Waterloo researchers unveil new screening tool and data at 2016 AAIC

Liquid biopsies hold potential for detecting NSCLC EGFR mutations, predicting cancer recurrence

Menopause and insomnia could make women age faster

Identifying new pathway of EZH2 gene may lead to targeted therapies for aggressive breast cancer

Researchers detect high levels of arsenic, chromium and kidney injury biomarker in children of Mexico

JAD announces recipient of 2016 Alzheimer Award

Expanding the potential of existing cancer therapies: an interview with Dr Mark Rutstein

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

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