Central Nervous System News and Research

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Researchers image a biomarker of neurogenesis

Mirjana Maletic-Savatic, M.D., Ph.D, and co-investigators from Stony Brook University Medical Center, Brookhaven National Laboratory and Cold Spring Harbor Laboratory have discovered a way to image a biomarker of neural stem and progenitor cells (NPCs) in the living human brain.

13 Nov 2007

New target for MS treatment found using old drug

A drug currently used to treat high blood pressure and heart failure has been found to reduce the symptoms of multiple sclerosis in mice.

13 Nov 2007

Anti-inflammation molecule helps fight MS-like disease

An immune system messenger molecule that normally helps quiet inflammation could be an effective tool against multiple sclerosis (MS). Neurology researchers led by Abdolmohamad Rostami, M.D., Ph.D., professor and chair of the Department of Neurology at Jefferson Medical College of Thomas Jefferson University and the Jefferson Hospital for Neuroscience in Philadelphia, have found that the protein interkeukin-27 (IL-27) helped block the onset or reverse symptoms in animals with an MS-like disease.

13 Nov 2007

Could a new vaccine be the key to stopping Alzheimer's disease?

A new study from the Oklahoma Medical Research Foundation (OMRF) shows that immunization could offer a way to blunt or even prevent the deadly, memory-robbing disease.

13 Nov 2007

Research reveals critical knowledge about the nervous system

Uncover the neural communication links involved in myelination, the process of protecting a nerve's axon, and it may become possible to reverse the breakdown of the nervous system's electrical transmissions in such disorders as multiple sclerosis, spinal cord injuries, diabetes and cancers of the nervous system.

6 Nov 2007

Food fortification with folic acid linked to increased cancer rate

Two recent commentaries appearing in the November issue of Nutrition Reviews find that the introduction of flour fortified with folic acid into common foods was followed by an increase in colon cancer diagnoses in the U.S. and Canada.

5 Nov 2007

Carnegie Mellon researchers to develop new stem cell-based drug delivery therapy

Carnegie Mellon University's Stefan F. Zappe is using adult neural stem cells to develop a new stem cell-based drug delivery therapy that may ultimately help treat a variety of inherited genetic disorders like Hunter syndrome.

5 Nov 2007

New guideline recommends when to use CT scans in ER for seizures

A guideline developed by the American Academy of Neurology recommends immediate brain CT scans to screen certain emergency room patients with seizures.

29 Oct 2007

Deep brain stimulation to treat Parkinson's makes some act irrationally

An implantable brain device meant to help Parkinson's disease patients better control their movements, has been found to have some worrying side-effects.

29 Oct 2007

Therapeutic gene expression can be sustainable for 1 year

Researchers at the Board of Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have shown for the first time that it is possible to sustain therapeutic gene expression in the central nervous system for up to a year, even in the presence of an anti-viral immune response mechanism that is normally present in humans.

28 Oct 2007

Medical College of Wisconsin receives grant to study infantile hemangiomas

The Food and Drug Administration (FDA) has awarded the Medical College of Wisconsin in Milwaukee a three-year, $1 million Orphan Products Development grant to study infantile hemangiomas – a vascular tumor of the skin or internal organs.

25 Oct 2007

Orexigen presents findings on obesity drug candidates

Orexigen Therapeutics, Inc., a biopharmaceutical company focused on the treatment of central nervous system (CNS) disorders including obesity, has presented the results of a preclinical study that further supports the Company's understanding of an aspect of the mechanism of action of Contrave, one of its two late-stage obesity drug candidates.

24 Oct 2007

West Nile virus' spread through nerve cells linked to serious complication

Scientists believe they have found an explanation for a puzzling and serious complication of West Nile virus infection.

19 Oct 2007

Mayo Clinic clarifies diagnosis for primary central nervous system vasculitis (PCNSV)

Mayo Clinic has clarified the methods of diagnosis and optimal management of a rare and little-understood blood vessel disease of the brain and spinal cord that often leads to stroke or death.

19 Oct 2007

FDA details safe sources for imported puffer fish

The U.S. Food and Drug Administration has released consumer and industry advisories regarding safe sources of puffer fish.

19 Oct 2007

Mental disorders are disorders of the brain

Depression, anxiety disorders such as panic disorder and obsessive-compulsive disorders, alcohol and drug dependence, dementia and Parkinson's disease are just a few examples of "disorders of the brain".

17 Oct 2007

The importance of the endocannabinoid-system

Cannabis (marijuana) is the most widely produced plant-based illicit drug worldwide and the illegal drug most frequently used in Europe.

15 Oct 2007

Familial multiple sclerosis appears more severe than non-familial

Magnetic resonance images (MRI) of a large group of patients with multiple sclerosis has provided the first evidence that those with a history of MS in their families show more severe brain damage than patients who have no close relatives with the disease.

15 Oct 2007

Cigarette smoking may accelerate disability in multiple sclerosis

Persons with multiple sclerosis who smoke risk increasing the amount of brain tissue shrinkage, a consequence of MS, and the subsequent severity of their disease, new research conducted at the Buffalo Neuroimaging Analysis Center (BNAC) at the University at Buffalo has shown.

15 Oct 2007

Antibody repairs myelin in lab study of multiple sclerosis and related disorders

Mayo Clinic researchers have found that a human antibody administered in a single low dose in laboratory mouse models can repair myelin, the insulating covering of nerves that when damaged can lead to multiple sclerosis and other disorders of the central nervous system.

10 Oct 2007