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Sun Biomedical begins DMX-200 Phase II trial for treatment of chronic kidney disease

Sun Biomedical Limited today announced the first patient had been enrolled in a Phase II study of DMX-200, an innovative new treatment that combines two different drugs to treat chronic kidney disease.

15 Sep 2015

New technique could improve selectivity of cancer drugs, decrease unwanted side effects in future

A class of therapeutic drugs known as protein kinase inhibitors has in the past decade become a powerful weapon in the fight against various life-threatening diseases, including certain types of leukemia, lung cancer, kidney cancer and squamous cell cancer of the head and neck.

11 Sep 2015

Luteolin may reduce risk of breast cancer in some women, find MU researchers

More than 100 women die from breast cancer every day in the United States. The odds increase in postmenopausal women who have taken a combined estrogen and progestin hormone replacement therapy; these women also have an increased risk of developing progestin-accelerated breast tumors.

11 Sep 2015

FGF21 compound in breast milk plays key role in neonatal nutrient absorption, intestinal function

A compound found in breast milk, named fibroblast growth factor 21 (FGF21), plays a key role in neonatal nutrient absorption and intestinal function. FGF21 also contributes to improve newborn growth and metabolic profile.

11 Sep 2015

Rice lab invents technique to characterize nanoscale spaces in porous materials

Rice University scientists led a project to "see" and measure the space in porous materials, even if that space is too small or fragile for traditional microscopes.

10 Sep 2015

Compound responsible for chilis' heat may help kill prostate cancer cells

Capsaicin, the compound responsible for chilis' heat, is used in creams sold to relieve pain, and recent research shows that in high doses, it kills prostate cancer cells. Now researchers are finding clues that help explain how the substance works. Their conclusions suggest that one day it could come in a new, therapeutic form.

10 Sep 2015

Researchers use stem cell-derived 'mini-brains' to identify drug candidate for rare neurological disorder

Using "mini-brains" built with induced pluripotent stem cells derived from patients with a rare, but devastating, neurological disorder, researchers at University of California, San Diego School of Medicine say they have identified a drug candidate that appears to "rescue" dysfunctional cells by suppressing a critical genetic alteration.

9 Sep 2015

Three drug-like compounds may offer better odds of survival to patients with prostate cancer, find SMU researchers

Researchers at Southern Methodist University, Dallas, have discovered three new drug-like compounds that could ultimately offer better odds of survival to prostate cancer patients.

9 Sep 2015

DNDi announces successful completion of SCYX-7158 Phase I study for treatment of sleeping sickness

The Drugs for Neglected Diseases initiative (DNDi) has announced today at the 9th European Congress on Tropical Medicine and International Health in Basel, Switzerland, the successful completion of Phase I human clinical trials for SCYX-7158 (AN5568), the first oral drug candidate specifically developed from the earliest drug discovery stage to combat human African trypanosomiasis, or sleeping sickness, a deadly parasitic disease transmitted by the tsetse fly.

9 Sep 2015

Researchers identify new way to help AML patients avoid a relapse

A protein domain once considered of little importance may be key to helping patients who are fighting acute myeloid leukemia (AML) avoid a relapse.

8 Sep 2015

Demand for improved capabilities, wireless connectivity drives Western and Eastern European MPM market

As the Western European multiparameter patient monitor (MPM) market is in its mature stage, it will generate most of its revenues from replacement units. On the other hand, the Eastern European market, which has not reached maturity, will predominantly see new MPM installations.

8 Sep 2015

Inhibiting key protein involved in glucose production may help in treating type 2 diabetes

Some treatments for type 2 diabetes make the body more sensitive to insulin, the hormone that lowers blood sugar. But new research at Washington University School of Medicine in St. Louis suggests a different strategy: slowing the production of glucose in the liver.

4 Sep 2015

Novel approach to reduce 'bad' lipids in blood circulation

Xian-Cheng Jiang, PhD, professor of cell biology at SUNY Downstate Medical Center, has led a study identifying a new approach for lowering "bad" lipids in blood circulation, a critical means to combat devastating cardiovascular diseases such as atherosclerosis. The research was published in the online edition of Gastroenterology.

3 Sep 2015

ISU researcher examines how supplements, resistance training improve muscle strength in older adults

The loss of muscle strength and function, what's known as sarcopenia, is a natural part of aging. It's also a growing public health concern because of the risk for falls, injury and decline in quality of life. That's why an Iowa State University researcher is working to slow or reverse the progression of sarcopenia.

3 Sep 2015

Voalte secures $17 million in Series D funding

Voalte, the leader in healthcare communication technology, today announced a new capital infusion of $17 million by Ascension Ventures, Cerner Capital, Inc., an affiliate of Cerner Corporation, and Bedford Funding. Series D funding closed on July 27, 2015, bringing the total capital Voalte has raised to nearly $60 million in three years.

2 Sep 2015

Phase III trial results show cariprazine effective in treating negative symptoms associated with schizophrenia

Results of a clinical trial seem to show the first effective treatment for the negative symptoms - withdrawal, lack of emotion, and apathy - associated with schizophrenia.

31 Aug 2015

Particulate matter, NO2 air pollution associated with increased risk of heart attacks

Particulate matter and NO2 air pollution are associated with increased risk of severe heart attacks despite being within European recommended levels, according to research presented at ESC Congress today by Dr Jean-Francois Argacha, a cardiologist at University Hospital Brussels (UZ Brussel-Vrije Universiteit Brussel), in Belgium.

31 Aug 2015

Researchers successfully use alcohols as reagents in alkylation reaction

Researchers at Princeton have developed a dual catalyst system that directly installs alkyl groups--fragments containing singly bonded carbon and hydrogen atoms that have extremely useful properties for drug discovery--onto compounds called heteroarenes. The new reaction uses simple and abundant alcohols and offers a milder and more widely applicable alternative to existing strategies.

28 Aug 2015

New ORNL interface can identify, characterize solid or liquid sample

In mere seconds, a system developed at the Department of Energy's Oak Ridge National Laboratory can identify and characterize a solid or liquid sample, providing a valuable tool with applications in material science, forensics, pharmaceuticals, biology and chemistry.

27 Aug 2015

Purple potatoes may help prevent colon cancer

Compounds found in purple potatoes may help kill colon cancer stem cells and limit the spread of the cancer, according to a team of researchers.

27 Aug 2015

Compound News and Research

Sun Biomedical begins DMX-200 Phase II trial for treatment of chronic kidney disease

New technique could improve selectivity of cancer drugs, decrease unwanted side effects in future

Luteolin may reduce risk of breast cancer in some women, find MU researchers

FGF21 compound in breast milk plays key role in neonatal nutrient absorption, intestinal function

Rice lab invents technique to characterize nanoscale spaces in porous materials

Compound responsible for chilis' heat may help kill prostate cancer cells

Researchers use stem cell-derived 'mini-brains' to identify drug candidate for rare neurological disorder

Three drug-like compounds may offer better odds of survival to patients with prostate cancer, find SMU researchers

DNDi announces successful completion of SCYX-7158 Phase I study for treatment of sleeping sickness

Researchers identify new way to help AML patients avoid a relapse

Demand for improved capabilities, wireless connectivity drives Western and Eastern European MPM market

Inhibiting key protein involved in glucose production may help in treating type 2 diabetes

Novel approach to reduce 'bad' lipids in blood circulation

ISU researcher examines how supplements, resistance training improve muscle strength in older adults

Voalte secures $17 million in Series D funding

Phase III trial results show cariprazine effective in treating negative symptoms associated with schizophrenia

Particulate matter, NO2 air pollution associated with increased risk of heart attacks

Researchers successfully use alcohols as reagents in alkylation reaction

New ORNL interface can identify, characterize solid or liquid sample

Purple potatoes may help prevent colon cancer

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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