Genetic Engineering News and Research

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New discovery helps explain complex neurocircuitry behind body weight control

A study led by a scientific team at Beth Israel Deaconess Medical Center (BIDMC) provides another important step in our understanding of the critical role that the brain's molecular pathways play in the development of obesity and related disorders.

7 Nov 2005

Protein called CHIP helps untangle protein misfolding in brain disease

Keeping the body and mind healthy depends on keeping cells healthy and functioning. This means that cells need a very robust quality-control system to repair or remove damaged or misshapen proteins. Protein handling is especially important in neurons because damage or death of brain cells causes neurological disease.

1 Nov 2005

How the brain tracks time is essential to understanding all its functions

The brain is a "time machine," assert Duke neuroscientists Catalin Buhusi and Warren Meck. And understanding how the brain tracks time is essential to understanding all its functions. The brain's internal clocks coordinate a vast array of activities from communicating, to orchestrating movement, to getting food, they said.

30 Oct 2005

Scientists unravel complex mechanisms in the brain that regulate body weight

Scientists are one step closer to unraveling the complex mechanisms in the brain that regulate body weight. Working with mice -- whose appetites are controlled by systems very similar to those in humans – they have identified a specific type of neuron that is essential for feeding behavior.

30 Oct 2005

FDA approves first transplant of fetal stem cells into human brains

The U.S. Food and Drug Administration has approved the first transplant of fetal stem cells into human brains, a procedure that if successful could pave the way to treating a host of neural disorders.

24 Oct 2005

Researchers discover the presence of functional ion channels in human embryonic stem cells

These ion channels act like electrical wires and permit ESCs, versatile cells that possess the unique ability to become all cell types of the body, to conduct and pass along electric currents.

20 Oct 2005

Molecule P-glycoprotein (Pgp), may help reduce risk of Alzheimer's

A molecule that has long been an obstacle to cancer chemotherapy and drug treatments for brain disorders may soon become an ally in the fight against Alzheimer's disease, according to researchers at Washington University School of Medicine in St. Louis and the University of Rochester.

20 Oct 2005

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

The humble yeast has revealed the molecular workings of an anti-cancer drug that stops the growth and spread of tumours in humans by starving their blood supply.

18 Oct 2005

Aβ and Fyn cooperate to cause Alzheimer-like changes in the brain

Reporting in two companion papers in the October 19 issue of the Journal of Neuroscience, investigators from the Gladstone Institute of Neurological Disease show in genetically engineered mouse models of the disease that the accumulation of Alzheimer-related neurotoxic amyloid-beta (Aâ) peptides can deplete key proteins in a specific memory center of the brain.

18 Oct 2005

Hormone responsible for types of high blood pressure could also cause preeclampsia

Researchers at the University of Cincinnati (UC) Academic Health Center have found evidence of a hormone they say is responsible for certain types of high blood pressure (hypertension), and could also cause preeclampsia, a potentially dangerous condition that occurs during pregnancy.

17 Oct 2005

New tool that may prove to be invaluable for investigating the long-term mutagenic effects of chemotherapy and radiation

Scientists have developed a new tool that may prove to be invaluable for investigating the long-term mutagenic effects of chemotherapy and radiation, therapies that are widely used for the treatment of cancer.

17 Oct 2005

Obesity associated with a threefold increase in SCD1 expression in obese muscle

The gene encoding an enzyme that hinders muscle from burning fat manufactures three times more enzyme in the muscle of obese people than lean people, researchers from Duke University Medical Center and Louisiana State University have found. This causes the obese muscle tissue to both store more fat and burn less fat, the researchers said.

11 Oct 2005

Scientists genetically modify male mosquitoes to express a glowing protein in their gonads - may help control the mosquito population

By providing a way to quickly sex mosquitoes, the advance paves the way for pooling large numbers of sterile males which could be used to control the mosquito population.

9 Oct 2005

Somatic adult stem cell niches - key regulators of stem cell activity in mammary tissue

Researchers at Georgetown's Lombardi Comprehensive Cancer Center have found that the onset of breast cancer may be due to defects in somatic adult stem cell niches that exist long before tumors develop.

4 Oct 2005

New light shed on the causes of drug addiction

A methamphetamine epidemic rages across the United States with addicts blinded by uncontrollable desires for a drug that eventually thrusts them into a dire and catastrophic existence. Doctors don't have any effective treatments for these addicts, or for any other drug addicts; drug addiction is a disease that remains a medical mystery.

4 Oct 2005

Genetic Engineering News and Research

New discovery helps explain complex neurocircuitry behind body weight control

Protein called CHIP helps untangle protein misfolding in brain disease

How the brain tracks time is essential to understanding all its functions

Scientists unravel complex mechanisms in the brain that regulate body weight

FDA approves first transplant of fetal stem cells into human brains

Researchers discover the presence of functional ion channels in human embryonic stem cells

Molecule P-glycoprotein (Pgp), may help reduce risk of Alzheimer's

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

Aβ and Fyn cooperate to cause Alzheimer-like changes in the brain

Hormone responsible for types of high blood pressure could also cause preeclampsia

New tool that may prove to be invaluable for investigating the long-term mutagenic effects of chemotherapy and radiation

Obesity associated with a threefold increase in SCD1 expression in obese muscle

Scientists genetically modify male mosquitoes to express a glowing protein in their gonads - may help control the mosquito population

Somatic adult stem cell niches - key regulators of stem cell activity in mammary tissue

New light shed on the causes of drug addiction

Farnesyl transferase inhibitors may help chidren with Hutchinson-Gilford progeria syndrome

Increlex - first major innovation in 20 years for the treatment of growth failure

Scientists reverse memory loss in mice with Alzheimer's

Next generation of effective viral-based therapies for cancer

Genetically engineered animals help in scientific research that may benefit children

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo