Pathogen News and Research

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New automated tool rapidly delivers large particles into mammalian cells

A new device developed by UCLA engineers and doctors eventually help scientists study the development of disease, enable them to capture improved images of the inside of cells and lead to other improvements in medical and biological research.

10 Apr 2015

NIAID funds nine research projects to advance rapid diagnostics tests for drug-resistant bacteria

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded more than $11 million in first-year funding for nine research projects supporting enhanced diagnostics to rapidly detect antimicrobial-resistant bacteria.

10 Apr 2015

Researchers identify phenomenon that explains effects of oxidative stress on immune cells

You're up in the mountains, the snow is blindingly white, and the sun is blazing down from the sky: ideal skiing conditions - but any skiers carrying the herpes virus might also have to reckon with the onset of cold sores after their day out.

10 Apr 2015

Seal Shield's new Airocide DS air purifier may help eliminate 'Super Bugs' in hospitals

Seal Shield LLC (Jacksonville, FL), today announced the new Airocide DS air purifier. The Airocide DS is a table top or bed side air purification product that uses a unique photocatalytic biocide reactor to eliminate viral, fungal and bacterial pathogens from the air. Developed by NASA, Airocide converts dangerous bacteria, virus and destructive VOC's into harmless water vapor without producing ozone or other harmful byproducts.

9 Apr 2015

Study may point to immediate cause of CF exacerbations

In the genetic disorder cystic fibrosis (CF), the most severe symptoms are recurring episodes of lung inflammation and bacterial infection (known as "exacerbations") that happen from one to three times a year and cause ever-increasing amounts of lung damage through the course of a CF patient's life.

9 Apr 2015

New approach could help identify novel drug targets to combat lethal fungal infections

By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically--an approach that could help identify novel targets for therapies against this serious pathogen for which there are a limited number of anti-fungal agents.

6 Apr 2015

Dartmouth researchers use new strategies to target drug-resistant pathogens

By engineering antibacterial enzymes, Dartmouth investigators led by Karl Griswold, PhD are using novel strategies to target the prevalent drug-resistant bacterium Staphylococcus aureus.

3 Apr 2015

Study examines efficacy of continuous UV-C robots versus pulsed xenon in preventing infection

The efficacy of continuous UV-C disinfection robots versus pulsed xenon (PU-UX) was highlighted in a recently published study of ultraviolet (UV) light disinfection systems by an influential infection prevention research team, including Curtis Donskey, M.D.

1 Apr 2015

New research reveals how a deadly fungus grows and kills immune cells

New research from the University of Toronto has scientists re-thinking how a lethal fungus grows and kills immune cells. The study hints at a new approach to therapy for Candida albicans, one of the most common causes of bloodstream infections.

31 Mar 2015

New approach allows researchers to trap and watch highly motile cells

Optical imaging of highly motile cells or cells in suspension, such as bacterial systems, yeast cells, and immune cells, is a challenging task, in many cases it is just not possible. The human immunodeficiency virus (HIV), for example, can spread very efficiently from an infected T cell to an uninfected T cell through direct cell-cell contact.

31 Mar 2015

Synthetic Biologics begins SYN-004 Phase 2a clinical trial to prevent C. difficile infection

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, today announced the initiation of a Phase 2a clinical trial to evaluate the gastrointestinal (GI) antibiotic-degrading effects and the safety of SYN-004, the Company's investigational oral beta-lactamase enzyme designed to protect the microbiome and prevent C. difficile infection (CDI).

30 Mar 2015

Study suggests new approach to help prevent meningococcal outbreaks

Nasal drops of harmless bacteria can inhibit a related bug that sometimes causes meningococcal disease, according to new findings published online in Clinical Infectious Diseases. The study--conducted among college students, a group at higher risk for this often serious illness--suggests a new approach that could help suppress outbreaks of the disease, if supported by future research.

30 Mar 2015

NYUCD receives NIH grant to develop POC test to detect HIV antibodies and viral RNA

New York University College of Dentistry has received a sub-award in the amount of $335,000 from a Small Business Innovation Research (SBIR) Phase II grant from the National Institutes of Health to complete the development of a fully automated self-confirming assay that can simultaneously detect HIV/AIDS antibodies and viral RNA from the AIDS virus in a single specimen.

29 Mar 2015

Key finding may point to immediate cause of CF exacerbations

24 Mar 2015

Study explains why COPD patients develop tolerance to roflumilast drug

Roflumilast, a drug recently approved in the United States to treat severe chronic obstructive pulmonary disease (COPD), increases the production of a protein that causes inflammation, which possibly results in patients developing a tolerance to the drug after repeated use and makes the drug less effective, according to researchers at Georgia State University, Kumamoto University and the University of Rochester Medical Center.

24 Mar 2015

Pathogen may cause high levels of virulence in closely-related hosts

When viruses such as influenza and Ebola jump from one species to another, their ability to cause harm can change dramatically, but research from the University of Cambridge shows that it may be possible to predict the virus's virulence by looking at how deadly it is in closely-related species.

23 Mar 2015

Two common antibiotic treatments equally effective against MRSA skin infections

Researchers funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, have found that two common antibiotic treatments work equally well against bacterial skin infections caused by methicillin-resistant Staphylococcus aureus (MRSA) acquired outside of hospital settings.

20 Mar 2015

New method of testing deadly pathogen could help combat cystic fibrosis

A new method of testing the most common cause of life-threatening infection in people with cystic fibrosis could improve efforts to study and combat the illness.

18 Mar 2015

Understanding strengths and weaknesses of hepatitis C viruses

Using a specially selected library of different hepatitis C viruses, a team of researchers led by Johns Hopkins scientists has identified tiny differences in the pathogens' outer shell proteins that underpin their resistance to antibodies.

12 Mar 2015

Researchers take images of tiny molecular machine that bacteria use to infect host cells

Armed with a microscope capable of zooming in on organisms measured in billionths of a meter, scientists report they are the first to observe one of the tiny molecular machines that bacteria use to infect host cells. Findings appear in the Proceedings of the National Academy of Sciences.

10 Mar 2015

Pathogen News and Research

New automated tool rapidly delivers large particles into mammalian cells

NIAID funds nine research projects to advance rapid diagnostics tests for drug-resistant bacteria

Researchers identify phenomenon that explains effects of oxidative stress on immune cells

Seal Shield's new Airocide DS air purifier may help eliminate 'Super Bugs' in hospitals

Study may point to immediate cause of CF exacerbations

New approach could help identify novel drug targets to combat lethal fungal infections

Dartmouth researchers use new strategies to target drug-resistant pathogens

Study examines efficacy of continuous UV-C robots versus pulsed xenon in preventing infection

New research reveals how a deadly fungus grows and kills immune cells

New approach allows researchers to trap and watch highly motile cells

Synthetic Biologics begins SYN-004 Phase 2a clinical trial to prevent C. difficile infection

Study suggests new approach to help prevent meningococcal outbreaks

NYUCD receives NIH grant to develop POC test to detect HIV antibodies and viral RNA

Key finding may point to immediate cause of CF exacerbations

Study explains why COPD patients develop tolerance to roflumilast drug

Pathogen may cause high levels of virulence in closely-related hosts

Two common antibiotic treatments equally effective against MRSA skin infections

New method of testing deadly pathogen could help combat cystic fibrosis

Understanding strengths and weaknesses of hepatitis C viruses

Researchers take images of tiny molecular machine that bacteria use to infect host cells

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