Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Metabolic pathway activates cell signaling protein to promote breast cancer metastasis

A metabolic pathway that is up-regulated in certain breast cancers promotes the disease's progression by activating a cell signaling protein called Arf6, according to a paper published in the Journal of Cell Biology.

7 Apr 2016

Health benefits of gastric bypass surgery start soon after procedure

The health benefits of Roux-en Y gastric bypass surgery—a surgical weight-loss procedure in which the stomach is made smaller—start soon after the procedure. New research presented today at the Experimental Biology 2016 meeting in San Diego found that patients who underwent the procedure already showed some reductions in weight, waist circumference and body mass index one week after the procedure.

7 Apr 2016

Person's age, mobility could be powerful predictors of survival than certain biomarkers

Advances in technology allow scientists to measure intricate details about the human body that greatly enhance understanding of health, disease and aging.

7 Apr 2016

Scientists find new way to inhibit growth of tuberculosis-causing bacterium

Scientists at the The University of Queensland and the University of California San Francisco have found a new way to inhibit the growth of the bacterium that causes tuberculosis (TB).

6 Apr 2016

Better management of blood sugar, blood pressure and LDL-cholesterol levels could reduce cardiovascular risk

While controlling blood pressure, blood sugar and LDL-cholesterol levels reduces the risk of cardiovascular disease in people with diabetes, only 7 percent of diabetic participants in three major heart studies had recommended levels of these three factors, according to research from the Heart Disease Prevention Program at the University of California, Irvine School of Medicine.

6 Apr 2016

Researchers identify possible genetic basis for coronary artery disease

For many people, coronary artery disease, or CAD—the buildup of plaque in the heart's arteries—is an unfortunate part of aging. By studying the genetic makeup of those who manage to maintain clear arteries into old age, researchers have identified a possible genetic basis for the disease, as well as potential new opportunities to prevent it.

6 Apr 2016

Regular exercise can stave off health problems associated with sedentary time

Office workers can stave off health problems associated with sitting down all day by regularly exercising, a new study has found.

5 Apr 2016

Adding liraglutide to diet and exercise plan may help people lose weight, reduce diabetes risk

For people with prediabetes who are overweight or obese, adding 3.0 mg of liraglutide for three years to a diet and exercise plan may lead to major health improvements, new industry-sponsored research suggests. The results will be presented Monday, April 4, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston.

5 Apr 2016

Evolocumab could be more effective than ezetimibe in lowering cholesterol in statin-intolerant patients

In the first major trial of its kind, Cleveland Clinic researchers used a blinded rechallenge with atorvastatin or placebo to objectively confirm the presence of muscle-related symptoms in patients with a history of intolerance to multiple statins and found that evolocumab (a PCSK9 inhibitor) was a more effective option to lower cholesterol than ezetimibe in these patients.

4 Apr 2016

Daily walnut consumption positively impacts blood cholesterol levels in older adults

Initial findings from the Walnuts and Healthy Aging study presented at Experimental Biology 2016 (EB) indicate that daily walnut consumption positively impacts blood cholesterol levels without adverse effects on body weight among older adults.

4 Apr 2016

Apple body shape linked to higher heart risk than pear-shape in diabetics

People with type 1 or 2 diabetes who have apple-shaped bodies with excessive fat around the abdomen and stomach, can be at higher risk of serious heart disease than patients with pear-shaped figures who store excess fat around their hips, according to a new study from Intermountain Medical Center Heart Institute and John Hopkins University.

4 Apr 2016

Study demonstrates rarity of familial hypercholesterolemia mutations in individuals with high cholesterol

Only a small fraction of people with very high cholesterol can attribute their condition to a genetic mutation related to familial hypercholesterolemia, but individuals with these mutations face a high risk of developing early-onset coronary artery disease, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Researchers compare lipid-lowering efficacy for two nonstatin therapies in statin-intolerant patients

Steven E. Nissen, M.D., of the Cleveland Clinic, and colleagues identified patients with muscle-related adverse effects from statins and compared lipid-lowering efficacy for two nonstatin therapies, ezetimibe and evolocumab. The study was published online by JAMA, and is being released to coincide with its presentation at the American College of Cardiology's 65th Annual Scientific Session & Expo.

4 Apr 2016

Cholesterol drug evacetrapib fails to reduce risk of cardiovascular events

Despite lowering low-density lipoprotein (LDL), known as "bad" cholesterol, while markedly increasing levels of high-density lipoprotein (HDL), or "good" cholesterol, a large clinical trial to investigate the cholesterol drug evacetrapib was discontinued early after a preliminary analysis showed it did not reduce rates of major adverse cardiovascular events, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

DNA changes may affect a person's lifespan

Scientists have identified DNA changes that can cut a person's lifespan by up to three years.

31 Mar 2016

Eating pulses helps people lose weight, show researchers

Eating just one serving of pulses a day is enough to help people lose weight and keep that weight off, according to a new study.

31 Mar 2016

Study demonstrates possibility of simultaneous improvement in all mental, physical functions

Let's say you've decided to make some changes in your life. You're out of shape, your mind wanders, your self-esteem is wavering, and you have no idea what you just read. So you decide to focus on one thing -- losing weight, maybe -- and tackle the other issues later. You don't want to take on too much at once, right?

26 Mar 2016

Only few U.S. adults maintain healthy lifestyle, research finds

Only 2.7 percent of the U.S. adult population achieves all four of some basic behavioral characteristics that researchers say would constitute a "healthy lifestyle" and help protect against cardiovascular disease, a recent study concluded.

22 Mar 2016

Research sheds new light on genetic relationship between ASD and ASD-related traits in wider population

New light has been shed on the genetic relationship between autistic spectrum disorders (ASD) and ASD-related traits in the wider population, by a team of international researchers including academics from the University of Bristol, the Broad Institute of Harvard and MIT, and Massachusetts General Hospital.

22 Mar 2016

Stress management can cut risk of another heart attack by half

Patients recovering from heart attacks or other heart trouble could cut their risk of another heart incident by half if they incorporate stress management into their treatment, according to research from Duke Health.

22 Mar 2016

Cholesterol News and Research

Further Reading

Metabolic pathway activates cell signaling protein to promote breast cancer metastasis

Health benefits of gastric bypass surgery start soon after procedure

Person's age, mobility could be powerful predictors of survival than certain biomarkers

Scientists find new way to inhibit growth of tuberculosis-causing bacterium

Better management of blood sugar, blood pressure and LDL-cholesterol levels could reduce cardiovascular risk

Researchers identify possible genetic basis for coronary artery disease

Regular exercise can stave off health problems associated with sedentary time

Adding liraglutide to diet and exercise plan may help people lose weight, reduce diabetes risk

Evolocumab could be more effective than ezetimibe in lowering cholesterol in statin-intolerant patients

Daily walnut consumption positively impacts blood cholesterol levels in older adults

Apple body shape linked to higher heart risk than pear-shape in diabetics

Study demonstrates rarity of familial hypercholesterolemia mutations in individuals with high cholesterol

Researchers compare lipid-lowering efficacy for two nonstatin therapies in statin-intolerant patients

Cholesterol drug evacetrapib fails to reduce risk of cardiovascular events

DNA changes may affect a person's lifespan

Eating pulses helps people lose weight, show researchers

Study demonstrates possibility of simultaneous improvement in all mental, physical functions

Only few U.S. adults maintain healthy lifestyle, research finds

Research sheds new light on genetic relationship between ASD and ASD-related traits in wider population

Stress management can cut risk of another heart attack by half

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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