Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Stony Brook researcher receives grant to evaluate daily activity levels, heart rate patterns of CFS patients

By better understanding daily activity levels and heart rate patterns of those who suffer from Chronic Fatigue Syndrome (CFS), scientists hope to discover more about this complex illness condition.

24 Jun 2016

Protein-based CHD risk score developed

Researchers have screened over 1000 plasma proteins to develop a predictive score in patients with stable coronary heart disease.

22 Jun 2016

Potential therapeutic approaches to combat chronic myeloid leukemia

Chronic myeloid leukemia (CML) develops through chromosomal alterations in blood-forming cells of the bone marrow and usually occurs in older persons. Around 20 percent of adults diagnosed with leukemia suffer from this type of blood cancer.

21 Jun 2016

Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

Gestational diabetes can put babies at a lifelong risk for cardiovascular disease, and scientists want to better understand how.

21 Jun 2016

E-cigarette use modifies gene expression important for upper airway immune defense

When we smoke cigarettes, dozens of genes important for immune defense are altered in the epithelial cells that line the respiratory tract. Several of these changes likely increase the risk of bacterial infections, viruses, and inflammation.

21 Jun 2016

Diabetic mothers three times more likely to have anti-fetal brain autoantibodies

Mothers of children with autism and were diagnosed with metabolic conditions during pregnancy, particularly gestational and type 2 diabetes, were more likely to have anti-fetal brain autoantibodies in their blood compared to healthy women of children with autism.

20 Jun 2016

ERCC2 validated as chemotherapy response biomarker in bladder cancer

Somatic mutations in the helicase-encoding ERCC2 gene are associated with response to neoadjuvant cisplatin-based chemotherapy in patients with muscle-invasive urothelial bladder carcinoma.

17 Jun 2016

Study finds link between chronic inflammation and premenstrual symptoms

Women with premenstrual symptoms (PMS) including mood swings, weight gain/bloating, and abdominal cramps/back pain have elevated levels of C-reactive protein (CRP), a biomarker of inflammation associated with increased risk of cardiovascular disease.

17 Jun 2016

New superbug test developed by TGen-NAU receives Australian patent

Antibiotic-resistant infections should be easier to detect, and hospitals could become safer, thanks to a technology developed by the Translational Genomics Research Institute and Northern Arizona University, and protected under a patent issued by Australia.

16 Jun 2016

Potential non-invasive screening biomarker for SSc-PAH

Serum asymmetric dimethylarginine may be an effective non-invasive screening biomarker for systemic sclerosis-related pulmonary arterial hypertension, study findings indicate.

16 Jun 2016

Mayo researchers develop extremely precise assay to measure age-associated changes in GDF11

Researchers at Mayo Clinic have developed an accurate way to measure a circulating factor, called GDF11, to better understand its potential impact on the aging process.

15 Jun 2016

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Non-small cell lung cancers have a collective reputation for not responding very well to chemotherapy. Researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) are presenting a means of evaluating an immunotherapy that fights off NSCLC by strengthening a patient's own immune system.

14 Jun 2016

PET imaging can help identify autoimmune inflammation in MS

The triggers of autoimmune inflammation in multiple sclerosis (MS) have eluded scientists for many years, but molecular imaging is bringing researchers closer to identifying them, while providing a means of evaluating next-generation therapies for MS, say researchers introducing a study at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

14 Jun 2016

Anti-TNF therapy offers new hope to JDM patients

The results of a UK study presented today at the European League Against Rheumatism Annual Congress showed that tumour necrosis factor inhibitor (anti-TNF) treatment is effective at improving both muscle and skin involvement in children with juvenile dermatomyositis (JDM).

13 Jun 2016

Advanced imaging technique helps predict recovery in concussion patients

Using an advanced imaging technique, researchers at Albert Einstein College of Medicine and Montefiore Health System were able to predict which patients who'd recently suffered concussions were likely to fully recover.

10 Jun 2016

Simple blood test can help track rising levels of eosinophils linked to regrowth of sinus polyps

In an effort to identify a simple, reliable way to track the course of nasal polyps in chronic sinus disease, Johns Hopkins Medicine researchers say they've linked rising levels of immune system white blood cells, called eosinophils, with regrowth of polyps removed by surgery.

9 Jun 2016

New technology can detect KRAS gene mutations, facilitate targeted therapies for lung and colorectal cancers

A new technology suitable for practical clinical testing can detect KRAS gene mutations in lung and colorectal cancers and could thereby facilitate targeted therapies, according to a new report in The Journal of Molecular Diagnostics.

8 Jun 2016

Life Extension, Insilico Medicine team up to identify novel biomarkers of human aging

Life Extension (use different web link to highlight our technical attributes), a Florida-based organization established in the early 1980s is dedicated to extending healthy human longevity.

8 Jun 2016

New blood test helps detect MCI stage of Alzheimer's disease

A research team, led by Dr. Robert Nagele from Rowan University School of Osteopathic Medicine and Durin Technologies, Inc., has announced the development of a blood test that leverages the body's immune response system to detect an early stage of Alzheimer's disease - referred to as the mild cognitive impairment (MCI) stage - with unparalleled accuracy.

8 Jun 2016

Innovative RapifleX MALDI-TOF/TOF showcased by Bruker

At the 64th ASMS Conference, Bruker introducesrapifleX™, the highest performance MALDI-TOF/TOF mass spectrometer, which had been shown as work-in-progress to early adopters at HUPO 2015.

From Bruker Daltonics 7 Jun 2016

Biomarker News and Research

Further Reading

Stony Brook researcher receives grant to evaluate daily activity levels, heart rate patterns of CFS patients

Protein-based CHD risk score developed

Potential therapeutic approaches to combat chronic myeloid leukemia

Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

E-cigarette use modifies gene expression important for upper airway immune defense

Diabetic mothers three times more likely to have anti-fetal brain autoantibodies

ERCC2 validated as chemotherapy response biomarker in bladder cancer

Study finds link between chronic inflammation and premenstrual symptoms

New superbug test developed by TGen-NAU receives Australian patent

Potential non-invasive screening biomarker for SSc-PAH

Mayo researchers develop extremely precise assay to measure age-associated changes in GDF11

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

PET imaging can help identify autoimmune inflammation in MS

Anti-TNF therapy offers new hope to JDM patients

Advanced imaging technique helps predict recovery in concussion patients

Simple blood test can help track rising levels of eosinophils linked to regrowth of sinus polyps

New technology can detect KRAS gene mutations, facilitate targeted therapies for lung and colorectal cancers

Life Extension, Insilico Medicine team up to identify novel biomarkers of human aging

New blood test helps detect MCI stage of Alzheimer's disease

Innovative RapifleX MALDI-TOF/TOF showcased by Bruker

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