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EU-funded project investigates molecular mechanisms of aging in adult stem cells

Stem cells are the ultimate mother cells of the human body. Not only do they have the capacity to self-renew, they can develop into specific cell types as the body requires. But as the human body ages, the regenerative capacity of our stem cells diminishes.

8 Feb 2019

'Satellite' stem cells more likely to develop into fat cells after rotator cuff tears

Why are fat deposits more likely to occur after tears of the shoulder's rotator cuff, compared to other types of muscle injuries? An increased propensity of stem cells within with rotator cuff muscles to develop into fat cells may explain the difference, reports a study in the February 6, 2019 issue of The Journal of Bone & Joint Surgery.

7 Feb 2019

Review: Antibiotic development has increased, but inadequate

While the pipeline of new antibiotics has improved over the past six years, momentum in the development of new infection-fighting agents remains inadequate and could take a significant downturn without new incentives, a report released in Clinical Infectious Diseases shows.

7 Feb 2019

First therapy indicated for treating adults with rare blood clotting disorder receives FDA approval

The U.S. Food and Drug Administration today approved Cablivi (caplacizumab-yhdp) injection, the first therapy specifically indicated, in combination with plasma exchange and immunosuppressive therapy, for the treatment of adult patients with acquired thrombotic thrombocytopenic purpura (aTTP), a rare and life-threatening disorder that causes blood clotting.

7 Feb 2019

Vitamin D helps clear bacteria from lungs of people with multi-drug resistant TB

Vitamin D has been found to speed up the clearance of tuberculosis bacteria from the lungs of people with multi-drug resistant TB, according to a study of 1,850 patients receiving antibiotic treatment, led by Queen Mary University of London.

6 Feb 2019

New review examines impact of cancer therapies on the skeleton

A new British Journal of Clinical Pharmacology review examines the impact of cancer therapies on the skeleton and how to limit bone loss and fractures in cancer patients treated with these therapies.

6 Feb 2019

Simulation model to find the most optimal cancer treatment

In ten years, computers will be able to propose the most suitable cancer treatment for you. The idea is to simulate how all possible combinations of existing cancer treatments will work on your particular tumor.

6 Feb 2019

Fractures have prolonged effect on older adults' quality of life

Single and multiple hip, vertebral, and rib fractures strongly affect the quality of life of older adults over a prolonged period of time, according to a new study published in the Journal of Bone and Mineral Research.

6 Feb 2019

Early ancestors' taste for fat reveals new clues to human evolution

Long before human ancestors began hunting large mammals for meat, a fatty diet provided them with the nutrition to develop bigger brains, posits a new paper in Current Anthropology.

6 Feb 2019

Protein CDK6 appears to be key factor in influencing development of MPN

MPNs are a group of rare, malignant diseases of the bone marrow involving the production of an excess of red blood cells, white blood cells and/or platelets.

6 Feb 2019

Swedish patient becomes first recipient of novel implant to control dexterous hand prosthesis

A female Swedish patient with hand amputation has become the first recipient of an osseo-neuromuscular implant to control a dexterous hand prosthesis.

5 Feb 2019

Groundbreaking preventive approach promises to revolutionize treatment of rheumatoid arthritis

The EU- and industry-funded RTCURE project’s groundbreaking approach promises to revolutionise treatment of rheumatoid arthritis, which afflicts millions of people across Europe with joint pain, inflammation and bone and cartilage loss.

4 Feb 2019

New research uncovers crucial link between polyamines and MYCN

The MYCN oncogene has long been known to be a key cause of a number of deadly solid tumor cancers, including neuroblastoma, which claims more lives of children under the age of 5 than any other cancer.

4 Feb 2019

Researchers develop a new treatment for osteomyelitis

A team of researchers led by RCSI (Royal College of Surgeons in Ireland), have developed a new treatment for the particularly difficult-to-treat bone infection, osteomyelitis.

31 Jan 2019

Leukemia promotes premature aging in the bone marrow

Leukemia promotes premature aging in healthy bone marrow cells - according to new research from the University of East Anglia.

30 Jan 2019

New biomaterial-based autograft extender can help treat critical-sized bone defects

For complex injuries and other situations requiring bone grafts, the best available technique involves autologous bone harvesting and re-implantation at the site of regrowth.

30 Jan 2019

Researcher discovers blood vessel system in bones

A network of very fine blood vessels that connects bone marrow directly with the blood supply of the periosteum that was previously overlooked has now been discovered by Dr. Anika Grüneboom, a young researcher who is now working at Universitätsklinikum Erlangen.

30 Jan 2019

Bone News and Research

EU-funded project investigates molecular mechanisms of aging in adult stem cells

'Satellite' stem cells more likely to develop into fat cells after rotator cuff tears

Review: Antibiotic development has increased, but inadequate

First therapy indicated for treating adults with rare blood clotting disorder receives FDA approval

Vitamin D helps clear bacteria from lungs of people with multi-drug resistant TB

New review examines impact of cancer therapies on the skeleton

Simulation model to find the most optimal cancer treatment

Fractures have prolonged effect on older adults' quality of life

Early ancestors' taste for fat reveals new clues to human evolution

Protein CDK6 appears to be key factor in influencing development of MPN

Swedish patient becomes first recipient of novel implant to control dexterous hand prosthesis

Groundbreaking preventive approach promises to revolutionize treatment of rheumatoid arthritis

New research uncovers crucial link between polyamines and MYCN

Researchers develop a new treatment for osteomyelitis

Leukemia promotes premature aging in the bone marrow

New biomaterial-based autograft extender can help treat critical-sized bone defects

Researcher discovers blood vessel system in bones

Researchers uncover first spontaneous animal model of human hypophosphatasia

Using bivalves as model organisms offers promising avenues for medical research

Vitamin D may lower glucose levels and reduce risk of developing type 2 diabetes

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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