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Polyglycine aggregates disrupt tRNA splicing and drive neurodegeneration

Neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, are devastating and incurable diseases.

17 Jul 2025

Uncovering a protective RNA molecule in kidney stress and disease

Cells contain helper molecules called transfer RNAs (tRNAs), which carry building blocks (amino acids) to make proteins.

17 Jul 2025

From chemistry to life: Building synthetic cells with metabolism

At some point during the evolution of life on Earth, inorganic matter became organic, nonliving matter became living. How this happened is one of humankind's greatest mysteries.

17 Jul 2025

CRISPR-mediated DNA methylation editing regulates inflammation and tumor growth

Genes, fragments of DNA located on our chromosomes, control much of what happens in cells.

17 Jul 2025

Study reveals how aging alters liver function and structure

The aging liver undergoes dramatic changes in its functional organization and other key attributes, which may underpin its increasing susceptibility to disease, according to a study led by investigators at Weill Cornell Medicine.

17 Jul 2025

Scientists create liver organoids with functional blood vessels

Liver organoids with proper blood vessel networks have been successfully produced, as reported by researchers from Institute of Science Tokyo and Cincinnati Children's Hospital Medical Center.

17 Jul 2025

Galectin-3 identified as key driver of chemoresistance in pancreatic cancer

Pancreatic cancer is often diagnosed at an advanced stage and is characterized by a poor prognosis and rising mortality.

17 Jul 2025

Discovery of hybrid Aspergillus species with antifungal resistance in Japan

Aspergillus is a fungus that is commonly found in the environment, both indoors and outdoors. This fungus species can cause aspergillosis-a respiratory infection affecting the lungs. A. fumigatus, A. nidulans, and A. niger are some of the common species within the Aspergillus genus that cause aspergillosis.

17 Jul 2025

How can super-resolution technology help study neurotransmission?

Discover how super-resolution technology can be used to sudy neurotransmission at inhibitory synapses.

From Bruker Nano Surfaces and Metrology 17 Jul 2025

New molecular pathway identified in alcohol-associated liver disease

Excessive alcohol consumption causes alcoholic liver disease, and about 20% of these cases progress to alcohol-associated steatohepatitis (ASH), which can lead to liver cirrhosis and liver failure. Early diagnosis and treatment are therefore extremely important.

17 Jul 2025

Vaccinated women face fewer cervical cancer risks

The HPV vaccine demonstrates strong long-term protection against cervical cancer, yet the study underscores the necessity of ongoing screening for all women.

17 Jul 2025

Nuclear waste exposure in childhood associated with higher cancer incidence

Living near Coldwater Creek-a Missouri River tributary north of St. Louis that was polluted by nuclear waste from the development of the first atomic bomb-in childhood in the 1940s, '50s, and '60s was associated with an elevated risk of cancer, according to a new study led by Harvard T.H. Chan School of Public Health.

17 Jul 2025

New genetic marker improves kidney transplant match predictions

Researchers at the University of Pittsburgh have identified a new way of predicting whether a kidney donor and recipient are a good match for transplantation.

17 Jul 2025

New tech could revolutionize neurodegenerative disease research and AI

When electrical activity travels across the brain, it moves like ripples on a pond. The motion of these "brain waves," first observed in the 1920s, can now be seen more clearly than ever before thanks to instruments and techniques created by a Stanford-led team.

17 Jul 2025