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Newly established McClay Foundation to encourage healthcare research in Northern Ireland

Speaking last week Sir Allen McClay, Chairman of the Almac Group, formally announced the establishment of the McClay Foundation, a charitable trust, one of the first of its kind in Northern Ireland.

8 Sep 2009

Researchers discover benefits of treating Alzheimer's disease with cancer drug

A drug now used to treat cancer may also be able to restore memory deficits in patients with Alzheimer's disease, according to a new study conducted by scientists at Columbia University Medical Center, which appeared in the September issue of the Journal of Alzheimer's Disease: Volume 18:1.

8 Sep 2009

Cancer drug could restore memory deficits in Alzheimer's patients

7 Sep 2009

New role discovered for sphingosine-1-phosphate

Virginia Commonwealth University School of Medicine researchers have discovered a new role for the bioactive lipid messenger, sphingosine-1-phosphate, or S1P, that is abundant in our blood - a finding that could lead to a new generation of drugs to fight cancer and inflammatory disease.

5 Sep 2009

StemCells’ novel neuroprotective approach for treating neurodegenerative diseases

StemCells, Inc. today announced the publication of preclinical data demonstrating for the first time that transplantation of its proprietary, purified human neural stem cells delays the loss of motor function in a mouse model of infantile neuronal ceroid lipofuscinosis (NCL).

4 Sep 2009

BF STEM tomography allows to visualize fine details of cell structure

Scientists in the National Institute of Biomedical Imaging and Bioengineering (NIBIB) Laboratory of Bioengineering and Physical Science have developed a new technique that allows researchers to visualize fine details of cell structure three-dimensionally in thick sections, thus providing greater insight into how cells are organized and how they function. The work is described in a report published online this week in Nature Methods.

4 Sep 2009

Genetic cause of progressive hearing loss discovered

A team led by scientists from The Scripps Research Institute has discovered a genetic cause of progressive hearing loss. The findings will help scientists better understand the nature of age-related decline in hearing and may lead to new therapies to prevent or treat the condition.

4 Sep 2009

STEMCELL Technologies to conduct a two-day stem cell training program

STEMCELL Technologies has announced the schedule for their fall training program. This includes 2-day courses on mesenchymal stem cell biology (October 2nd and 3rd), mammary stem cell biology (October 17th and 18th), neural stem cell biology (October 30th and 31st), hematopoietic stem cell biology (October 30th and 31st), and human embryonic and induced pluripotent stem cell biology (November 14th and 15th).

2 Sep 2009

New study on behaviour of telomeres during cell division in cancerous human cells

A process that limits the number of times a cell divides works much differently than had been thought, opening the door to potential new anticancer therapies, researchers at UT Southwestern Medical Center report in the Aug. 7 issue of the journal Cell.

2 Sep 2009

The biology of apoE and apoE receptors in Alzheimer's disease to be researched under new NIH program

A researcher at the University of Illinois at Chicago College of Medicine has been awarded more than $9.8 million to head a five-year National Institute on Aging Program Project Grant.

2 Sep 2009

Elsevier publishes second edition of Signal Transduction

Elsevier, the world-leading publisher of scientific, technical and medical information products and services, announces the publication of the new second edition of Signal Transduction edited by Bastien D. Gomperts, Ijsbrand M. Kramer and Peter E.R. Tatham.

1 Sep 2009

Research journal to host a webinar on apoptotic signalling in normal and cancer cell biology

The business office of Science, the world's leading peer-reviewed research journal, is producing a webinar on "Apoptotic Signaling in Normal and Cancer Cell Biology" to be broadcast live online at 12 noon ET (4:00 GMT) September 22, 2009, sponsored by Promega.

29 Aug 2009

Chk1 and Fbx6 play an important role for the regulation of response to chemotherapy

Cell cycle checkpoints act like molecular tripwires for damaged cells, forcing them to pause and take stock. Leave the tripwire in place for too long, though, and cancer cells will press on regardless, making them resistant to the lethal effects of certain types of chemotherapy, according to researchers at the Salk Institute for Biological Studies.

28 Aug 2009

Diabetics can reduce the risk of cardiovascular disease by increasing vitamin D levels

Low levels of vitamin D are known to nearly double the risk of cardiovascular disease in patients with diabetes, and researchers at Washington University School of Medicine in St. Louis now think they know why.

24 Aug 2009

Researchers discover elusive nanoscale movements of ribosomes at work

Researchers at the University of California, Berkeley, have for the first time captured elusive nanoscale movements of ribosomes at work, shedding light on how these cellular factories take in genetic instructions and amino acids to churn out proteins.

24 Aug 2009

Novel microRNA plays a major role in invasive breast cancer development

Research led by Suresh Alahari, PhD, Associate Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, has shown for the first time that a tiny piece of RNA appears to play a major role in the development of invasive breast cancer and identified a gene that appears to inhibit invasive breast cancer.

20 Aug 2009

Scientists find another mechanism that destroys tumor cells

Cells don't like to be alone. In the early stages of tumor formation, a cell might be pushed out of its normal home environment due to excessive growth. But a cell normally responds to this homeless state by dismantling its nucleus, packing up its DNA, and offering itself to be eaten by immune system cells. Simply put, the homeless cell kills itself. This process, known as apoptosis, typically stops potential cancer cells before they have a chance to proliferate.

20 Aug 2009

Steroid hormones found to affect gene activity

Intermittent signaling by steroid hormones can affect the way genes are expressed in rodents, according to research by scientists at the University of Bristol and the National Cancer Institute (NCI), USA. This work has major implications for understanding how steroids work and opens novel avenues for new therapies.

19 Aug 2009

Protein Huwe1 may be an important factor in the development of brain cancer

Researchers from Columbia University Medical Center's Herbert Irving Comprehensive Cancer Center have identified a protein that activates brain stem cells to make new neurons - but that may be hijacked later in life to cause brain cancer in humans. The protein called Huwe1 normally functions to eliminate other unnecessary proteins and was found to act as a tumor suppressor in brain cancer.

17 Aug 2009

An "off switch" for cancer

New insight into how human cells reproduce, published by cancer researchers at Michigan State University and the Van Andel Research Institute in Grand Rapids, could help scientists move closer to finding an "off switch" for cancer.

12 Aug 2009