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NIH funding helps address pediatric disease gaps in clinical trials

The National Institutes of Health (NIH) serves as an important source of funding for clinical trials in children, especially for diseases, such as cancer, that are not as highly prioritized in industry-sponsored clinical trials, according to a recent study published in The Journal of Pediatrics.

3 Mar 2025

New brain imaging technique offers hope for better stroke rehabilitation

A new Georgetown University Medical Center study in collaboration with MedStar Health and the National Institutes of Health exploring a new brain imaging technique is bringing stroke experts a step closer to better tailoring rehabilitation.

3 Mar 2025

Epstein-Barr virus infection predisposes people to develop Crohn's disease

Crohn's disease, a debilitating inflammatory bowel disease, has many known contributing factors, including bacterial changes in the microbiome that foster an inflammatory environment.

3 Mar 2025

Synthetic microbiome therapy offers new hope against C. difficile infections

A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans, according to a team of researchers at Penn State.

3 Mar 2025

One-hour glucose tolerance test could revolutionize postpartum diabetes screening

Caring for a baby is a full-time job, often causing new mothers to overlook their own health needs. This situation is exemplified by the low compliance with postpartum glucose screening among women who had gestational diabetes-a condition that significantly increases their risk of developing type 2 diabetes later in life.

3 Mar 2025

Study elucidates mechanism connecting ER membrane remodeling to pyroptosis in cancer cells

Pyroptosis, a highly inflammatory type of programmed cell death, has garnered attention for its potential in cancer treatment.

3 Mar 2025

Talk therapy delivered by non-specialists effective for pregnant and postpartum individuals

Approximately one in five of pregnant and postpartum individuals experience depression and anxiety, yet less than 10 per cent receive proper treatment.

3 Mar 2025

Research reveals key parental risk factors for child abuse

Child maltreatment has been the focus of two separate studies led by UQ researchers, who examined the main parental risk factors that lead to child abuse, as well as the behavioural impacts later in life.

3 Mar 2025

Hallucinogen use linked to increased risk of mortality in emergency care patients

People seeking emergency care for hallucinogen use were at 2.6-fold higher risk of death within 5 years than the general population, according to a new study published in CMAJ.

3 Mar 2025

Sleep patterns could indicate hidden consciousness in brain injury patients

Several studies in the past decade have revealed that up to a quarter of unresponsive patients with recent brain injuries may possess a degree of consciousness that's normally hidden from their families and physicians.

3 Mar 2025

New blood biomarkers could revolutionize gallbladder cancer diagnosis

Researchers at Karolinska Institutet and Karolinska University Hospital have identified biomarkers in the blood that can be used to distinguish gallbladder cancer from inflammation of the gallbladder.

3 Mar 2025

Skin organoids show promise for treating frostbite injuries

Frostbite is a severe cold injury that affects millions worldwide, often resulting in prolonged recovery, scarring, and long-term complications such as chronic pain and dysfunction.

3 Mar 2025

Medtronic receives FDA approval for BrainSense Adaptive DBS technology

For the one million people diagnosed with Parkinson's disease in the United States, Medtronic plc (NYSE:MDT), a global leader in healthcare technology, proudly announces U.S. Food and Drug Administration (FDA) approval of BrainSense™ Adaptive deep brain stimulation (aDBS) and BrainSense™ Electrode Identifier (EI).

3 Mar 2025

Pioneering the world’s first CRISPR medicine for sickle cell disease

When Vijay Sankaran was an MD-PhD student at Harvard Medical School in the mid-2000s, one of his first clinical encounters was with a 24-year-old patient whose sickle cell disease left them with almost weekly pain episodes.

3 Mar 2025

New three-organ system offers an animal-free alternative for pharmacokinetics research

Innovative organ-on-chip specialist Dynamic42 and ESQlabs, experts in digital life sciences solutions, have successfully developed a three-organ system, in close collaboration with Consumer Health Division of Bayer, and the Placenta Lab at Jena University Hospital.

2 Mar 2025

New study confirms GLP-1 medications are safe for mental health in diabetes

Researchers assess whether GLP-1 receptor agonists increase the risk of suicide, self-harm, or suicidal ideation in type 2 diabetes patients.

2 Mar 2025

St. Jude scientists discover how retinoic acid selectively kills metastatic neuroblastoma cells

Neuroblastoma is a solid tumor that occurs in children. When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment increased survival by 10-15%.

2 Mar 2025

Researchers uncover how brain tumors reprogram neutrophils to hinder cancer treatment

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling further tumor growth.

2 Mar 2025

Maternity care costs significantly higher for racial and ethnic groups

A new study out today in JAMA Health Forum is the first to show that Black, Hispanic and Asian people with private insurance tend to pay more out-of-pocket for maternity care than white people.

28 Feb 2025

Understanding the benefits and risks of hyperbaric oxygen therapy

Hyperbaric oxygen therapy is well known for treating scuba and deep-sea divers affected by the rapid change in pressure around them. But did you know that HBOT is also used to treat a variety of other health problems, including carbon monoxide poisoning and diabetic foot ulcers?

28 Feb 2025