Sclerosis News and Research

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Glaucoma and cell death: an interview with Dr. Vivek Gupta

Glaucoma is normally caused by increased pressure of aqueous humour fluid in the eye. A defining feature of this disease is destruction of a particular type of cells in the retina called retinal ganglion cells and excavation of the optic disc region.

31 Aug 2012

Optimal cutoffs for defining pain in multiple sclerosis

A US study has identified optimal cutoffs for the definition of pain among individuals with multiple sclerosis.

30 Aug 2012

PrecisionMed announces enrollment of first donor into Amyotrophic Lateral Sclerosis Registry

PrecisionMed Inc., the world's leading supplier of human cerebrospinal fluid (CSF), today announced enrollment of the first donor into the PrecisionMed Amyotrophic Lateral Sclerosis (ALS) Registry.

30 Aug 2012

Novartis receives FDA approval for Afinitor Disperz to treat subependymal giant cell astrocytoma

The U.S. Food and Drug Administration today approved Afinitor Disperz (everolimus tablets for oral suspension), a new pediatric dosage form of the anti-cancer drug Afinitor (everolimus) used to treat a rare brain tumor called subependymal giant cell astrocytoma.

30 Aug 2012

EphA4 receptor may be promising target for future ALS drug

Leuven scientists (VIB/KU Leuven) are using zebrafish as a model in their search for genes that play a role in the mechanism of amyotrophic lateral sclerosis (ALS). As a result, they have identified a molecule that could be the target for a future ALS treatment.

28 Aug 2012

Study explains how breast milk fosters colonies of microbiotic flora in a newborn's intestinal tract

The benefits of breast milk have long been appreciated, but now scientists at Duke University Medical Center have described a unique property that makes mother's milk better than infant formula in protecting infants from infections and illnesses.

28 Aug 2012

Neuralstem completes NSI-566 Phase I trial on amyotrophic lateral sclerosis

Neuralstem, Inc. announced the completion of the Phase I trial of its NSI-566 spinal cord neural stem cells for the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), with the eighteenth patient treated.

28 Aug 2012

XJB-5-131 prevents secondary damage of severe traumatic brain injury

Treatment with an agent that blocks the oxidation of an important component of the mitochondrial membrane prevented the secondary damage of severe traumatic brain injury and preserved function that would otherwise have been impaired, according to a research team from the University of Pittsburgh School of Medicine, Graduate School of Public Health and Department of Chemistry in a report published online today in Nature Neuroscience.

27 Aug 2012

Profilin-1 gene influences survival time in Lou Gehrig's disease

A team of scientists, including faculty at the University of Massachusetts Medical School (UMMS), have discovered a gene that influences survival time in amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

27 Aug 2012

Genzyme receives Refuse to File letter from FDA for LEMTRADA

Genzyme, a Sanofi company, announced it has received a Refuse to File letter from the U.S. Food and Drug Administration (FDA) in response to the supplemental Biologics License Application (sBLA) for the approval of LEMTRADA (alemtuzumab) as a treatment for relapsing multiple sclerosis.

27 Aug 2012

Kineta receives regulatory clearance to commence ShK-186 Phase I trial in autoimmune disease

Seattle-based biotech company Kineta, Inc. announced today it has received regulatory clearance in the Netherlands to initiate a first-in-human trial of ShK-186, an autoimmune drug candidate that specifically inhibits the Kv1.3 potassium ion channel.

21 Aug 2012

House Bill 6218 would create interdepartmental autoimmune disease coordinating committee

Autoimmune disease patients received a win recently when U.S. Rep. Ann Marie Buerkle (R-NY) introduced House Bill 6218 to Congress. The bill would create an interdepartmental autoimmune disease coordinating committee.

21 Aug 2012

MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos

The MitoTarget Project was a project funded by the European Commission, under their FP7 programme. It was funding for a call published in 2007.

21 Aug 2012

Study demonstrates MRI role in defining and understanding causes of MS

New magnetic resonance imaging (MRI) research shows that changes in brain blood flow associated with vein abnormalities are not specific for multiple sclerosis (MS) and do not contribute to its severity, despite what some researchers have speculated. Results of the research are published online in the journal Radiology.

21 Aug 2012

Dendritic cells protect against MS in mouse model

In multiple sclerosis, the immune system attacks nerves in the brain and spinal cord, causing movement problems, muscle weakness and loss of vision. Immune cells called dendritic cells, which were previously thought to contribute to the onset and development of multiple sclerosis, actually protect against the disease in a mouse model, according to a study published by Cell Press in the August issue of the journal Immunity.

17 Aug 2012

Longer looks: A jack-of-all-trades surgeon takes care of Nantucket; Psychiatrist's controversial effort to use brain scans to diagnose mental problems

Dr. Tim Lepore, 67, is a jack-of-all-trades general surgeon, tending to the 10,000 full-time residents of the Massachusetts island of Nantucket and to the many thousand more rich and famous summer-dwellers. Dr. Lepore has dealt with everything from poison ivy and tick-borne illnesses to narcolepsy and toe tourniquet syndrome (when a mother's hair wraps around a baby's toe, cutting off circulation). He counsels alcoholics, and allows patients to barter for health care. He once accepted oatmeal cookies from an immigrant worker who had no money for treatment.

17 Aug 2012

Febrile seizures increase hippocampal injury risk

Children with febrile status epilepticus are at risk for hippocampal injury and show abnormalities in the development of this brain area, show findings from a prospective multicenter study.

16 Aug 2012

Kessler Foundation to present recent findings in spinal cord injury research at ASCIP conference

Scientists from Kessler Foundation are presenting recent findings in spinal cord injury research during Beyond Boundaries: the 2012 Conference of the Academy of Spinal Cord Injury Professionals (ASCIP).

16 Aug 2012

North Dakota State University student runs 400 miles to raise $10,000 for AARDA

North Dakota State University student, Ben Clark, is currently trekking 400 miles in an effort to raise $10,000 for the American Autoimmune Related Diseases Association (AARDA).

15 Aug 2012

Trial to test efficacy of NeuRx Diaphragm Pacing System in people with Lou Gehrig's disease

The Muscular Dystrophy Association (MDA) and The ALS Association today announced a joint commitment to provide funding for a phase 2 clinical trial that will test efficacy of the NeuRx Diaphragm Pacing System (DPS) in people with amyotrophic lateral sclerosis (ALS).

15 Aug 2012

Sclerosis News and Research

Glaucoma and cell death: an interview with Dr. Vivek Gupta

Optimal cutoffs for defining pain in multiple sclerosis

PrecisionMed announces enrollment of first donor into Amyotrophic Lateral Sclerosis Registry

Novartis receives FDA approval for Afinitor Disperz to treat subependymal giant cell astrocytoma

EphA4 receptor may be promising target for future ALS drug

Study explains how breast milk fosters colonies of microbiotic flora in a newborn's intestinal tract

Neuralstem completes NSI-566 Phase I trial on amyotrophic lateral sclerosis

XJB-5-131 prevents secondary damage of severe traumatic brain injury

Profilin-1 gene influences survival time in Lou Gehrig's disease

Genzyme receives Refuse to File letter from FDA for LEMTRADA

Kineta receives regulatory clearance to commence ShK-186 Phase I trial in autoimmune disease

House Bill 6218 would create interdepartmental autoimmune disease coordinating committee

MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos

Study demonstrates MRI role in defining and understanding causes of MS

Dendritic cells protect against MS in mouse model

Longer looks: A jack-of-all-trades surgeon takes care of Nantucket; Psychiatrist's controversial effort to use brain scans to diagnose mental problems

Febrile seizures increase hippocampal injury risk

Kessler Foundation to present recent findings in spinal cord injury research at ASCIP conference

North Dakota State University student runs 400 miles to raise $10,000 for AARDA

Trial to test efficacy of NeuRx Diaphragm Pacing System in people with Lou Gehrig's disease

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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