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YEDA and XL-protein sign deal to commercialize PASylated IFN superagonis

YEDA Research and Development Company Ltd., the technology transfer arm of the Weizmann Institute of Science, Israel, and XL-protein GmbH, Germany, a privately owned biopharmaceutical company, have signed a business collaboration agreement to commercialize a PASylated interferon superagonist -- PAS-YNSα8 -- which has been jointly developed by scientists at the Weizmann Institute and XL-protein.

21 Oct 2014

New preclinical imaging product line launched by MILabs at the 2014 Annual European Association of Nuclear Medicine Meeting

MILabs BV has launched a complete new preclinical product line at the 2014 Annual European Association of Nuclear Medicine Meeting in Gothenburg, Sweden, October 18-22 (www.eanm.org). It consists of the new 4-series comprising U-SPECT4, U-SPECT4CT, VECTor4 and VECTor4CT incorporating significant improvements over the former PLUS-series. The 4-series carries even further the tradition of MILabs to deliver the best SPECT and PET image resolution available in the market.

20 Oct 2014

Esophageal tissue can be grown in vivo from human and mouse cells, say researchers

In a first step toward future human therapies, researchers at The Saban Research Institute of Children's Hospital Los Angeles have shown that esophageal tissue can be grown in vivo from both human and mouse cells. The study has been published online in the journal Tissue Engineering, Part A.

20 Oct 2014

Anti-cancer nanomedicines with smaller sizes exhibit enhanced performance in vivo, show studies

Nanomedicines consisting of nanoparticles for targeted drug delivery to specific tissues and cells offer new solutions for cancer diagnosis and therapy.

17 Oct 2014

Cell transplantation treatment may benefit people with spinal cord injury

Two studies recently published in Cell Transplantation reveal that cell transplantation may be an effective treatment for spinal cord injury (SCI), a major cause of disability and paralysis with no current restorative therapies.

16 Oct 2014

Scientists combine new type of nanoparticle with photodynamic therapy to kill cancer cells

An international group of scientists led by Gang Han, PhD, at the University of Massachusetts Medical School, has combined a new type of nanoparticle with an FDA-approved photodynamic therapy to effectively kill deep-set cancer cells in vivo with minimal damage to surrounding tissue and fewer side effects than chemotherapy. This promising new treatment strategy could expand the current use of photodynamic therapies to access deep-set cancer tumors.

16 Oct 2014

LaVision BioTec report on users of light sheet microscopy in the Miami Project to Cure Paralysis

LaVison BioTec, developers of advanced microscopy solutions for the life sciences, report on users of their Ultramicroscope Light Sheet Fluorescence Microscope system to aid the research of the Miami Project to Cure Paralysis under the supervision of Professor Vance Lemmon, the Walter G. Ross Distinguished Chair in Developmental Neuroscience & Professor of Neurological Surgery at the University of Miami.

14 Oct 2014

Findings show that blockade of OGF-OGFr interfacing influences diabetic wound healing

A major complication associated with diabetes is delayed cell replication in epithelium and skin. Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have reported the presence and function of the opioid growth factor (OGF) and its nuclear-associated receptor (OGFr) in skin.

13 Oct 2014

New surface coating for medical devices prevents blood from clotting

From joint replacements to cardiac implants and dialysis machines, medical devices enhance or save lives on a daily basis. However, any device implanted in the body or in contact with flowing blood faces two critical challenges that can threaten the life of the patient the device is meant to help: blood clotting and bacterial infection.

13 Oct 2014

New research reveals innovative way to classify severity of stroke

New research conducted at the Florida State University-based National High Magnetic Field Laboratory has revealed a new, innovative way to classify the severity of a stroke, aid in diagnosis and evaluate potential treatments.

10 Oct 2014

VAL-083 drug compound shows promise against non-small cell lung cancer

DelMar Pharmaceuticals, Inc., a clinical-stage oncology company, today announced the presentation of promising new data supporting the activity of its lead drug compound, VAL-083, in the treatment of non-small cell lung cancer (NSCLC) at the AACR's New Horizons in Cancer Research: Harnessing Breakthroughs – Targeting Cures. The conference takes place October 9th to 12th in Pudong, Shanghai.

9 Oct 2014

HemoShear completes first-phase development of novel cancer drug discovery platform

HemoShear today announced that it has completed the first phase of development of a novel cancer drug discovery platform that replicates human tumor biology and responds to clinically-relevant drug concentrations.

9 Oct 2014

Researchers generate fruit fly model, unveil key genetic factors behind human colon cancer

Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have managed to generate a fruit fly (Drosophila melanogaster) model that reproduces human colon cancer. With two publications appearing in PLoS One and EMBO Reports, the IRB team also unveil the function of a key gene in the development of the disease.

9 Oct 2014

NIH announces winners of BRAIN Initiative awards

Today the National Institutes of Health (NIH) announced their first round of BRAIN Initiative awards, and six teams from the Massachusetts Institute of Technology (MIT) are among the recipients.

1 Oct 2014

Columbia Laboratories' subsidiary to unveil ROADMAP to Clinical Trials platform at CPhI/ICSE event

Columbia Laboratories, Inc., today announced that its subsidiary, Molecular Profiles Ltd., is set to unveil the ROADMAP to Clinical Trials platform at the annual CPhI/ICSE Worldwide event in Paris next week, which aims to support companies with the rapid development of both standard and complex drug products.

1 Oct 2014

Researchers create new Cas9 animal model for in vivo genome editing experiments

Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments.

29 Sep 2014

Study provides support for new understanding of the immune system

A study published in the journal Science provides support for a new-and still controversial-understanding of the immune system. The research was conducted by collaborators in the U.S. and Europe, including Robert Cramer, PhD, an assistant professor of microbiology and immunology at the Geisel School of Medicine and member of the Dartmouth Lung Biology Center, and Kelly Shepherdson, PhD, at the time a graduate student in Cramer's lab.

29 Sep 2014

Study finds that majority of athletes return to play after having knee surgery for ACL injury

The majority of athletes included in a new study by researchers at the University of North Carolina School of Medicine were able to return to play after having knee surgery to repair an anterior cruciate ligament (ACL) injury.

25 Sep 2014

Mfn2 protein: A future therapeutic target for neuronal death reduction in ischemic stroke

A new study published in the prestigious publication The EMBO Journal shows that the mitochondrial protein Mfn2 may be a future therapeutic target for neuronal death reduction in the late phases of an ischemic stroke.

24 Sep 2014

Activation of MMP-9 enzyme leads to behavioral problems connected to chronic stress

Why is it that when people are too stressed they are often grouchy, grumpy, nasty, distracted or forgetful? Researchers from the Brain Mind Institute at EPFL have just highlighted a fundamental synaptic mechanism that explains the relationship between chronic stress and the loss of social skills and cognitive impairment. When triggered by stress, an enzyme attacks a synaptic regulatory molecule in the brain. This was revealed by a work published in Nature Communications.

19 Sep 2014

in vivo News and Research

YEDA and XL-protein sign deal to commercialize PASylated IFN superagonis

New preclinical imaging product line launched by MILabs at the 2014 Annual European Association of Nuclear Medicine Meeting

Esophageal tissue can be grown in vivo from human and mouse cells, say researchers

Anti-cancer nanomedicines with smaller sizes exhibit enhanced performance in vivo, show studies

Cell transplantation treatment may benefit people with spinal cord injury

Scientists combine new type of nanoparticle with photodynamic therapy to kill cancer cells

LaVision BioTec report on users of light sheet microscopy in the Miami Project to Cure Paralysis

Findings show that blockade of OGF-OGFr interfacing influences diabetic wound healing

New surface coating for medical devices prevents blood from clotting

New research reveals innovative way to classify severity of stroke

VAL-083 drug compound shows promise against non-small cell lung cancer

HemoShear completes first-phase development of novel cancer drug discovery platform

Researchers generate fruit fly model, unveil key genetic factors behind human colon cancer

NIH announces winners of BRAIN Initiative awards

Columbia Laboratories' subsidiary to unveil ROADMAP to Clinical Trials platform at CPhI/ICSE event

Researchers create new Cas9 animal model for in vivo genome editing experiments

Study provides support for new understanding of the immune system

Study finds that majority of athletes return to play after having knee surgery for ACL injury

Mfn2 protein: A future therapeutic target for neuronal death reduction in ischemic stroke

Activation of MMP-9 enzyme leads to behavioral problems connected to chronic stress

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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