Antigen News and Research

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New study reveals CAR T cells can function as micro-pharmacies for precise therapeutic delivery

There has been much recent excitement about immunotherapy and the use of genetically engineered chimeric antigen receptor (CAR) T cells.

30 Sep 2016

Intermediate risk prostate cancer patients can achieve survival benefit with brachytherapy alone

For men with intermediate risk prostate cancer, radiation treatment with brachytherapy alone can result in similar cancer control with fewer long-term side effects, when compared to more aggressive treatment that combines brachytherapy with external beam therapy (EBT), according to research presented today at the 58th Annual Meeting the American Society for Radiation Oncology.

27 Sep 2016

Researchers identify, validate three distinct molecular subtypes of prostate cancer

In the largest study of its kind to date, researchers have identified and validated three distinct molecular subtypes of prostate cancer that correlate with distant metastasis-free survival and can assist in future research to determine how patients will respond to treatment, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

26 Sep 2016

Approval of PD-1 inhibitor scratches surface of potential immunotherapies in recurrent HNSCC

The recent approval of pembrolizumab (Keytruda) in recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) following progression on a platinum-based chemotherapy was a significant advancement for the disease.

26 Sep 2016

BBI Solutions introduces novel conjugate blocking technology to improve performance of lateral flow immunoassays

BBI Solutions has launched Morffi, a novel conjugate blocking technology that enhances signal intensity and improves the sensitivity of lateral flow immunoassays, at the Lateral Flow Test Development seminar in Seattle, USA, on the 20th September.

21 Sep 2016

Gender matching key for corneal transplants? An interview with Professor Kaye

The cornea is a transparent tissue lining the front of the eye, that is invisible tissue to the naked eye. It is a delicate tissue and disease or injury may lead to a loss of transparency or a change in the shape of the cornea, resulting in severe visual impairment.

19 Sep 2016

Researchers discover how mineral ion leaked from dying tumour tissue stops work of immune cells

Researchers at the National Cancer Institute in the USA and the Babraham Institute, UK, have discovered how a mineral ion leaked from tumour tissue as it dies acts to stop the work of anti-tumour immune cells.

18 Sep 2016

Research findings may pave way for innovative treatments of multiple sclerosis

Researchers at the Research Center for Immunotherapy and the Focus Program Translational Neurosciences of Johannes Gutenberg University Mainz have identified a new mechanism that is involved in the development of autoimmune diseases.

14 Sep 2016

Study shows possibility to achieve immunological antibody memory with mucosal vaccination

If a vaccine is to protect the intestines and other mucous membranes in the body, it also needs to be given through the mucosa, for example as a nasal spray or a liquid that is drunk.

14 Sep 2016

Using the immune system to fight cancer: an interview with Dr Charles Akle

We all produce as many as 100,000 different types of cancer cells every day, which are recognized and eliminated by our extraordinarily efficient immune system. However, if something goes wrong with the immune system, and it no longer gets rid of these cells, then that’s when cancerous cells grow and become a problem.

12 Sep 2016

CHORI scientists reveal improved protective antibody responses to new meningococcal vaccine

A study conducted by UCSF Benioff Children's Hospital Oakland Research Institute scientists shows greatly improved protective antibody responses to a new mutant vaccine antigen for prevention of disease caused by Neisseria meningitidis - also known as meningococcus - that has the potential to improve the current vaccines for meningitis.

9 Sep 2016

New biomarker test helps detect autoimmune-induced neuropsychiatric disorders

A research team from the University of Oklahoma Health Sciences Center, led by Madeleine Cunningham, Ph.D., in conjunction with the National Institute of Mental Health, has developed the first-of-its-kind biomarker test to help detect autoimmune-induced neuropsychiatric disorders.

9 Sep 2016

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

In a paper published today in Science Translational Medicine, researchers from Fred Hutchinson Cancer Research Center shared data from an early-phase study of patients with advanced non-Hodgkin lymphoma (NHL) who received JCAR014, a Chimeric Antigen Receptor (CAR) T cell treatment, and chemotherapy.

9 Sep 2016

Stealth insulin-producing pig cells may offer solution for treating Type 1 diabetes in humans

University of Alabama at Birmingham researchers are exploring ways to wrap pig tissue with a protective coating to ultimately fight diabetes in humans. The nano-thin bilayers of protective material are meant to deter or prevent immune rejection.

8 Sep 2016

Study finds cord blood transplant recipients appear to have better outcomes against leukemia

Umbilical cord blood transplants may have advantages beyond offering an alternative stem cell source for leukemia patients without a traditional donor match, according to a study published today in The New England Journal of Medicine.

8 Sep 2016

PSA failure linked to increased risk of death among healthy men

A new study by investigators at Brigham and Women's Hospital has found that a rise in prostate-specific antigen (PSA) levels in healthy men who have previously been treated for prostate cancer is significantly associated with a 1.6-fold increased risk of death.

6 Sep 2016

New research may explain why people with blood group O get more severely ill from cholera

People with blood type O often get more severely ill from cholera than people of other blood types. New research from Washington University School of Medicine in St. Louis may explain why.

29 Aug 2016

Leading Chikungunya vaccine in clinical trial phase 2

With the first patient vaccinated, a Phase 2 clinical trial of a promising prophylactic vaccine candidate against Chikungunya fever has now commenced. The product is the most advanced Chikungunya vaccine candidate globally and is developed by the Austrian biotech company Themis Bioscience GmbH.

29 Aug 2016

Fiocruz to start phase II clinical trials of novel vaccine for schistosomiasis

The Oswaldo Cruz Foundation at Rio de Janeiro, Brazil, will start the phase II clinical trials of a vaccine for schistosomiasis, called 'Sm14 Vaccine'.

26 Aug 2016

Naturally-occurring sugars in woman's breast milk may protect infants against life threatening bacteria

A type of sugar found naturally in some women's breast milk may protect newborn babies from infection with a potentially life threatening bacterium called Group B streptococcus, according to a new study from Imperial College London.

26 Aug 2016

Antigen News and Research

New study reveals CAR T cells can function as micro-pharmacies for precise therapeutic delivery

Intermediate risk prostate cancer patients can achieve survival benefit with brachytherapy alone

Researchers identify, validate three distinct molecular subtypes of prostate cancer

Approval of PD-1 inhibitor scratches surface of potential immunotherapies in recurrent HNSCC

BBI Solutions introduces novel conjugate blocking technology to improve performance of lateral flow immunoassays

Gender matching key for corneal transplants? An interview with Professor Kaye

Researchers discover how mineral ion leaked from dying tumour tissue stops work of immune cells

Research findings may pave way for innovative treatments of multiple sclerosis

Study shows possibility to achieve immunological antibody memory with mucosal vaccination

Using the immune system to fight cancer: an interview with Dr Charles Akle

CHORI scientists reveal improved protective antibody responses to new meningococcal vaccine

New biomarker test helps detect autoimmune-induced neuropsychiatric disorders

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

Stealth insulin-producing pig cells may offer solution for treating Type 1 diabetes in humans

Study finds cord blood transplant recipients appear to have better outcomes against leukemia

PSA failure linked to increased risk of death among healthy men

New research may explain why people with blood group O get more severely ill from cholera

Leading Chikungunya vaccine in clinical trial phase 2

Fiocruz to start phase II clinical trials of novel vaccine for schistosomiasis

Naturally-occurring sugars in woman's breast milk may protect infants against life threatening bacteria

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