Clinical Trial News and Research

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New $5.3 million NIH grant will support researchers into understanding lung cancer recurrence

Researchers at Washington University School of Medicine in St. Louis are leading a national study aimed at identifying patients with early-stage lung cancer who are at high risk of having the cancer return, even after surgery and chemotherapy appear to have eliminated their tumors.

28 Jun 2022

Phase 1 clinical trial of new influenza vaccine begins at NIH Clinical Center in Bethesda

A Phase 1 clinical trial of a novel influenza vaccine has begun inoculating healthy adult volunteers at the National Institutes of Health Clinical Center in Bethesda, Maryland.

28 Jun 2022

Innovative treatment reduces post-traumatic headache related disability, study finds

The first therapy to be developed specifically for post-traumatic headache significantly reduced related disability in veterans following a traumatic brain injury (TBI).

27 Jun 2022

Investigating PREVENT-19 trial findings of serological correlates of immune protection and risk against COVID-19

Researchers presented the PREVENT-19 phase 3 trial findings on the effectiveness of the NVX-CoV2373 adjuvanted, recombinant S nanoparticle vaccine.

27 Jun 2022

MD Anderson announces collaborative alliance with Turning Point Therapeutics to advance new treatment options for cancer patients

The University of Texas MD Anderson Cancer Center and Turning Point Therapeutics, Inc., today announced a strategic research and development alliance to expand the evaluation of two of Turning Point's investigational small molecules focusing on precision medicine targets well known in oncology.

24 Jun 2022

Updated Cochrane Review: No evidence to support the use of ivermectin for treating COVID-19 infection

There remains no evidence to support the use of ivermectin for treating or preventing COVID-19 infection, state the authors of an updated Cochrane Review, which now contains 11 trials across 3409 people.

24 Jun 2022

Study finds a more effective treatment option for HER2 mutant metastatic breast cancer

Breast cancers with HER2 mutations respond to the drug neratinib, but the responses are variable and often not durable.

23 Jun 2022

Henry Ford Health participated in a completely virtual heart failure study during the pandemic

Henry Ford Health was part of a multi-institutional heart failure study that was launched and executed completely virtual during the COVID-19 pandemic. The novel study design could serve as a model for future research.

23 Jun 2022

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Colorectal, pancreatic, esophageal and stomach cancers - some of the deadliest kinds of cancer - have high recurrence rates where the cancer comes back even after successful surgery or radiation treatment.

23 Jun 2022

Researchers identify biomarkers that could be targets for novel drugs to treat glioblastoma

Biomarkers that could be targets for novel drugs to treat glioblastoma brain tumors have been identified by investigators at Georgetown Lombardi Comprehensive Cancer Center, providing hope for a cancer that is highly lethal.

22 Jun 2022

Simple blood test can predict liver cancer risk in NAFLD patients

An estimated one-quarter of adults in the U.S. have nonalcoholic fatty liver disease (NAFLD), an excess of fat in liver cells that can cause chronic inflammation and liver damage, increasing the risk of liver cancer.

22 Jun 2022

RUDN doctors propose an alternative method of surgical management of glaucoma

RUDN University doctors have proposed an alternative method of surgical management of glaucoma. The main risk factor of glaucoma is increased pressure in the eye.

22 Jun 2022

Using air filters at home can reduce negative impacts of air pollution on children's brain development

A new study finds that having a portable air cleaner in the home can reduce the negative impacts of air pollution on brain development in children.

22 Jun 2022

New weight loss treatment is marked by heavy marketing and modest results

First came the "edible billboard," which appeared last year during the holidays in New York's East Village loaded with cake treats. Then, in late January, came the national marketing campaign, with TV and digital media promoting the idea that trying to lose weight doesn't mean a person can't enjoy eating.

22 Jun 2022

New pain medications with high abuse potential more likely to be successfully developed

Despite the prevalence and societal costs of pain in the United States, investment in pain medication development is low, due in part to poor understanding of the probability of successful development of such medications

21 Jun 2022

Simplicity is key when it comes to ablation, global AFib study finds

Results from one of the largest global studies of atrial fibrillation (AFib) procedures show that the simple approach is usually best when it comes to ablation, a procedure where physicians destroy or ablate cardiac tissue to correct irregular heart rhythms.

21 Jun 2022

Insufficient drug exposure most likely to cause COVID-19 rebound

Paxlovid is the leading oral medication for preventing severe cases of COVID-19 in high-risk individuals.

21 Jun 2022

Erectile dysfunction drugs may be able to boost the effect of chemotherapy in esophageal cancer

A group of drugs commonly used to treat erectile dysfunction may be able to boost the effect of chemotherapy in esophageal cancer, according to new research funded by Cancer Research UK and the Medical Research Council.

21 Jun 2022

Breast cancer trial results may not translate to real-world outcomes based on treatment discontinuation

New research in the June 2022 issue of JNCCN - Journal of the National Comprehensive Cancer Network raises issues with clinical trial findings that show adjuvant hormone therapy (AHT)-related hot flashes predict better outcomes for estrogen receptor-positive (ER+) breast cancer.

21 Jun 2022

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

Researchers evaluated the efficacy of PHELA, a traditional African drug, against SARS-CoV-2 in vitro.

21 Jun 2022

Clinical Trial News and Research

New $5.3 million NIH grant will support researchers into understanding lung cancer recurrence

Phase 1 clinical trial of new influenza vaccine begins at NIH Clinical Center in Bethesda

Innovative treatment reduces post-traumatic headache related disability, study finds

Investigating PREVENT-19 trial findings of serological correlates of immune protection and risk against COVID-19

MD Anderson announces collaborative alliance with Turning Point Therapeutics to advance new treatment options for cancer patients

Updated Cochrane Review: No evidence to support the use of ivermectin for treating COVID-19 infection

Study finds a more effective treatment option for HER2 mutant metastatic breast cancer

Henry Ford Health participated in a completely virtual heart failure study during the pandemic

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Researchers identify biomarkers that could be targets for novel drugs to treat glioblastoma

Simple blood test can predict liver cancer risk in NAFLD patients

RUDN doctors propose an alternative method of surgical management of glaucoma

Using air filters at home can reduce negative impacts of air pollution on children's brain development

New weight loss treatment is marked by heavy marketing and modest results

New pain medications with high abuse potential more likely to be successfully developed

Simplicity is key when it comes to ablation, global AFib study finds

Insufficient drug exposure most likely to cause COVID-19 rebound

Erectile dysfunction drugs may be able to boost the effect of chemotherapy in esophageal cancer

Breast cancer trial results may not translate to real-world outcomes based on treatment discontinuation

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

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