Genetic Engineering News and Research

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Direct link between inefficient metabolism and atherosclerosis

An experiment that turned out very differently than expected led scientists at Washington University School of Medicine in St. Louis to the first direct link between inefficient metabolism and atherosclerosis.

26 May 2005

Findings demonstrate that abnormal expression of the BCL6 gene causes lymphoma

This advancement has the potential to significantly speed the development of new, improved therapies for diffuse large B cell lymphoma (DLBCL), the most common type of human B cell lymphoma. Human B cell lymphomas cause 85 percent of non-Hodgkin’s lymphomas, the sixth leading cause of cancer deaths in the United States.

23 May 2005

Secrets of how the brain is wired for sex revealed

There are two brain structures that a mouse just can't do without when it comes to hooking up with the mate of its dreams--and trying to stay off the lunch menu of the neighborhood cat. These are the amygdala, which is involved in the initial response to cues that signal love or war, and the hypothalamus, which coordinates the innate reproductive or defensive behaviors triggered by these cues.

23 May 2005

Study holds implications for gene therapy and stem cell biology

The study, conducted by scientists from Cincinnati Children's Hospital Medical Center, and Hannover Medical School and Hamburg University in Germany, reveals important evidence that tells us more about how blood forming stem cells regenerate. On the other hand, scientists offer caution in regards to the side effects associated with genetic engineering of stem cells.

20 May 2005

Disease progression model of pancreatic cancer developed

Building on previous work, researchers at the University of Pennsylvania School of Medicine have developed an animal model of pancreatic cancer that closely mimics disease progression in humans. From this, they hope to develop new treatments for this deadly disease.

20 May 2005

Genetically modified rice will not eliminate hunger in China

Boosting food production with genetically modified (GM) rice is unlikely to eliminate hunger in China, states an editorial in this week’s issue of The Lancet.

19 May 2005

Unrestrained retina too much of a good thing

When primitive nerve cells begin forming an eye in the mouse embryo, they are programmed to build a retina. But the ability to see depends upon connecting the retina to the brain via the optic nerve. Unless these embryonic cells are given the right cue at the right time, they mistakenly form a huge eye that consists entirely of retina and lacks the optic nerve.

18 May 2005

Researchers create the first mouse model that develops a lymphoma the same way that humans do

This advancement has the potential to significantly speed the development of new, improved therapies for diffuse large B cell lymphoma (DLBCL), the most common type of human B cell lymphoma. Human B cell lymphomas cause 85 percent of non-Hodgkin's lymphomas, the sixth leading cause of cancer deaths in the United States.

17 May 2005

Rearing sea sponges that contain substances of interest to the pharmaceutical industry

Dutch researcher Nicole de Voogd has investigated the possibilities for rearing sea sponges in Indonesia. Some of these sponges contain substances of interest to the pharmaceutical industry. As these are increasingly difficult to obtain, there is growing interest in alternative methods of exploitation, such as rearing sponges.

15 May 2005

New fat is needed to clear old fat from the system

Where fat comes from determines whether the body can metabolize it effectively. Researchers at Washington University School of Medicine in St. Louis have found that the "old" fat stored in the body's peripheral tissues -- that is, around the belly, thighs or bottom -- can't be burned efficiently unless "new" fat is eaten in the diet or made in the liver.

9 May 2005

New treatment improves visual acuity score of patients with retinitis pigmentosa

Neurotech SA announced positive results from an open-label Phase I clinical trial (03-EI-0234) of its lead product, NT-501. NT-501 uses Neurotech’s patented Encapsulated Cell Technology (ECT) as a device to deliver ciliary neurotrophic factor (CNTF) to eyes of visually impaired patients with retinitis pigmentosa (RP). Neurotech is a biotechnology company specializing in the development of novel therapeutics to treat diseases of the eye. The company is headquartered in Paris.

8 May 2005

Nutritious cranberries good for the heart as well

Researchers say that cranberries improve the health of pigs’ hearts and may do the same for humans.

8 May 2005

GM mice live longer and give hope for anti-aging treatments

U.S. scientists have produced genetically modified mice that live 20 per cent longer than normal and may have possibly discovered an approach to extending the human lifespan.

8 May 2005

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

A powerful laboratory technique used by fruit fly geneticists for more than a decade is now available to scientists studying genes and diseases in mice.

5 May 2005

Genetically modified rice in China benefits farmers' health

Farmers growing genetically modified rice in field trials in China report higher crop yields, reduced pesticide use and fewer pesticide-related health problems, according to a study by researchers in China and at the University of California, Davis, and Rutgers University.

4 May 2005

Researchers make new advances in determining the structure of all possible DNA sequences

Oregon State University researchers have made significant new advances in determining the structure of all possible DNA sequences – a discovery that in one sense takes up where Watson and Crick left off, after outlining in 1953 the double-helical structure of this biological blueprint for life.

3 May 2005

Substantially more effective therapy than current treatments for Alzheimer's disease

PET scans and cognitive tests have suggested that Alzheimer's disease patients with genetically modified tissue inserted directly into their brains show a reduction in the rate of cognitive decline and increased metabolic activity in the brain, according to a study published in the April 24, 2005 online issue of the journal Nature Medicine by researchers at the University of California, San Diego (UCSD) School of Medicine.

25 Apr 2005

Maxim Pharmaceuticals issued patent for method of identifying therapeutically effective immunosupressive agents

Maxim Pharmaceuticals have announced the United States Patent and Trademark Office issued U.S. patent number 6,828,091 B2, entitled "Method of Identifying Immunosuppressive Agents."

23 Apr 2005

Insights could yield new approaches to nerve regeneration

Nervous system development requires billions of neurons to migrate to the appropriate locations in the brain and grow nerve fibers (axons) that connect to other nerve cells in an intricate network.

20 Apr 2005

Researchers insert engineered human stem cells into the spinal cords of ALS-afflicted rats

Unveiling a delivery method that may one day help surgeons treat the deadly neurodegenerative disease amyotrophic lateral sclerosis (ALS), researchers at the University of Wisconsin-Madison have inserted engineered human stem cells into the spinal cords of ALS-afflicted rats.

19 Apr 2005

Genetic Engineering News and Research

Direct link between inefficient metabolism and atherosclerosis

Findings demonstrate that abnormal expression of the BCL6 gene causes lymphoma

Secrets of how the brain is wired for sex revealed

Study holds implications for gene therapy and stem cell biology

Disease progression model of pancreatic cancer developed

Genetically modified rice will not eliminate hunger in China

Unrestrained retina too much of a good thing

Researchers create the first mouse model that develops a lymphoma the same way that humans do

Rearing sea sponges that contain substances of interest to the pharmaceutical industry

New fat is needed to clear old fat from the system

New treatment improves visual acuity score of patients with retinitis pigmentosa

Nutritious cranberries good for the heart as well

GM mice live longer and give hope for anti-aging treatments

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

Genetically modified rice in China benefits farmers' health

Researchers make new advances in determining the structure of all possible DNA sequences

Substantially more effective therapy than current treatments for Alzheimer's disease

Maxim Pharmaceuticals issued patent for method of identifying therapeutically effective immunosupressive agents

Insights could yield new approaches to nerve regeneration

Researchers insert engineered human stem cells into the spinal cords of ALS-afflicted rats

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