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First functional insulin-binding protein in invertebrates

Insulin-like growth factor (IGF) signaling that helps to regulate mammals' growth, metabolism, reproduction and longevity is well documented. Now research published in the open access journal Journal of Biology describes the genetic identification of the first functional insulin-like growth factor binding protein (IGFBP) ortholog in invertebrates.

17 Apr 2008

New clues to cataract formation

It is the No. 1 line-item cost of Medicare reimbursement and affects more than 20 million people in the United States. Cataracts, which can have devastating effects on the eye, affect 42 percent of the population between the ages of 70 and 80, and 68 percent of the population over the age of 80, according to the National Eye Institute.

17 Apr 2008

2nd Alzheimer's vaccine by AFFiRiS

The Viennese biotech company Affiris is today taking stock of the progress achieved to date in its clinical Alzheimer's vaccination programme. All the Alzheimer's patients treated so far as part of the toxicological trials have tolerated the treatment extremely well. As a result, Affiris is among the leading international centres in the race to develop the first causal immunotherapy for Alzheimer's disease.

17 Apr 2008

Biomarkers allow doctors to match therapy to patient

Genetic variations ensure that no two people are exactly alike, nor are their cancers.

13 Apr 2008

Gene oppositely controlled by dietary protein, sugar

Researchers have discovered a gene in flies whose activity rises and falls depending upon the amount of protein and sugar in the insects' diets.

9 Apr 2008

Blood pressure enzyme can have tumor-sensing role

By increasing production of a blood pressure-regulating enzyme in mice, researchers have found they can enhance the mouse immune system's ability to sense tumor growth.

8 Apr 2008

Synthetic molecules may be less expensive alternative to therapeutic antibodies

Researchers at UT Southwestern Medical Center have developed a simple and inexpensive method to screen small synthetic molecules and pull out a handful that might treat cancer and other diseases less expensively than current methods.

7 Apr 2008

New type of imaging system illuminates tumors to nearly one-trillionth of a meter

Doctors' quest to see what is happening inside a living body has been hampered by the limits on detecting tiny components of internal structures and events.

1 Apr 2008

Researchers make colorectal screening a little easier

Colon cancer screening is a tough sell. It's icky, uncomfortable and the thought of a colonoscopy, especially the prep, can be intimidating, to say the least.

25 Mar 2008

What change does prokineticin 2/Bv8 have in human hepatocellular carcinoma?

Liver hepatocarcinoma is a highly vascularized cancer, and more and more research is focused on the molecules controlling angiogenesis.

19 Mar 2008

Survival mechanism of T lymphocytes uncovered

When an individual is challenged by a virus, a bacterium or any other infectious agent, several classes of white blood cells are being activated in order to fight the invasion.

19 Mar 2008

Increased hepcidin expression: A novel oncogenic signalling mechanism

Historically anaemia, which is associated with colorectal cancer, has been attributed to blood loss.

19 Mar 2008

Study explains fundamental process of tumor growth

Nearly 80 years ago, scientist Otto Warburg observed that cancer cells perform energy metabolism in a way that is different from normal adult cells.

14 Mar 2008

Simple laboratory test predicts risk of kidney injury after surgery

A simple laboratory test may provide a new way for doctors to identify patients at risk of developing potentially severe acute kidney injury (AKI) after surgery up to three days before the problem would otherwise be detected, reports a pilot study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology .

14 Mar 2008

Study helps explain how tumor cells rapidly grow and proliferate

Nearly 80 years ago, scientist Otto Warburg observed that cancer cells perform energy metabolism in a way that is different from normal adult cells.

13 Mar 2008

Research could put penicillin back in battle against antibiotic resistant bugs

Research led by the University of Warwick has uncovered exactly how the bacterium Streptococcus pneumoniae has become resistant to the antibiotic penicillin.

13 Mar 2008

Simple laboratory test predicts risk of kidney injury after surgery

13 Mar 2008

Caspase-12: MUHC researcher finds new defense mechanism against intestinal inflammation

The body's first line of defence against pathogenic bacteria that we ingest may not be the immune system but rather the cells that line the intestine.

13 Mar 2008

Anadis licenses antibody technologies from ImmuCell

Anadis Limited, an Australian-based biotechnology company focused on milk derived polyclonal antibodies and other milk-derived bioactives, announced today that it had signed a final agreement with ImmuCell Corporation, a biotechnology company headquartered in Portland, Maine, USA.

11 Mar 2008

Long-term effects of synthetic progestins cause for concern

The widely used synthetic progestin medroxyprogesterone acetate (MPA) decreased endothelial function in premenopausal women in a study done at the University of Oregon.

11 Mar 2008