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New drugs show promise in shrinking breast cancer brain metastases

Researchers from Drexel's College of Medicine have identified new drugs that show early success in shrinking breast cancer tumors that have metastasized in the brain.

18 Jul 2024

Understanding the impact of tobacco smoking and smoking cessation on life expectancy of HIV patients in South Africa

Krishna Reddy, MD, MS, a physician-investigator at the Medical Practice Evaluation Center and the Tobacco Research and Treatment Center at Massachusetts General Hospital and an Associate Professor of Medicine at Harvard Medical School, is the senior author of a recently published paper in Journal of the International AIDS Society: Tobacco Smoking, Smoking Cessation and Life Expectancy Among People with HIV on Antiretroviral Therapy in South Africa: A Simulation Modelling Study.

16 Jul 2024

Predicting behavior from image features: Insights from cortical tuning

Researchers investigate whether the human occipital-temporal cortex (OTC) co-represents the semantic and affective content of visual stimuli to guide behavior.

15 Jul 2024

Bacterial communication system aids survival against antibiotics

When confronted with an antibiotic, toxic substance, or other source of considerable stress, bacteria are able to activate a defense mechanism using cell-to-cell communication to 'warn' unaffected bacteria, which can then anticipate, shield themselves and spread the warning signal.

10 Jul 2024

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Researchers discovered that interferon-stimulated SAMD9L restricts HIV-1 and other lentiviruses by inhibiting viral translation and endosomal trafficking, while SAMD9 enhances HIV-1 replication.

7 Jul 2024

Enhancing heart failure management with cardiac magnetic resonance imaging

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Heart failure (HF) is a clinical syndrome with a wide variety of clinical presentations, pathophysiologies, and natural histories.

4 Jul 2024

New HIV test targets neglected strains in global cure hunt

A multinational team led by Weill Cornell Medicine investigators developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa - a vital tool in the search for an HIV cure that will benefit patients around the world.

3 Jul 2024

Innovative HIV vaccine approaches yield potential for broad protection against viral strains

A major challenge in developing a vaccine for HIV is that the virus mutates fast - very fast. Although a person initially becomes infected with one or a few HIV strains, the virus replicates and mutates quickly, resulting in a "swarm" of viral strains existing in a single body.

2 Jul 2024

ERC Advanced Grant aids study on ubiquitin in DNA repair and genome stability

Professor Helle Ulrich, Executive Director of the Institute of Molecular Biology (IMB) and professor at Johannes Gutenberg University Mainz (JGU), has been awarded an Advanced Grant from the European Research Council (ERC).

28 Jun 2024

Young gay Latinos see rising share of new HIV cases, leading to call for targeted funding

Four months after seeking asylum in the U.S., Fernando Hermida began coughing and feeling tired. He thought it was a cold.

24 Jun 2024

Study reveals critical role of ADGRF5 in maintaining glomerular filtration barrier integrity

Glomerulus, the fundamental filtering unit of the kidney, is an intricate network of capillaries - small blood vessels that regulate the movement of ions, water, and metabolites while maintaining impermeability to essential macromolecules such as proteins.

21 Jun 2024

Repurposing anti-retroviral medications for brain tumor treatment: The RETREAT trial

Drugs developed to combat HIV and AIDS are being trialed for the first time in patients with multiple brain tumors.

21 Jun 2024

UT Health Science Center awarded $1.58M grant to study cancer disparities among Black women

A $1.58 million grant will support work by a health communication scholar at the University of Tennessee (UT) Health Science Center's College of Nursing and a medical oncologist at West Cancer Center and Research Institute (WCCRI) to identify sociocultural and structural factors that are root causes of cancer health disparities for Black women in the Mid-South.

20 Jun 2024

Federal nutrition initiative can offer infant feeding support and counseling to disabled parents

Infant feeding, involving breastfeeding, formula feeding, and the introduction of solid foods, is crucial for parenting.

19 Jun 2024

Personalized medicine approaches for sepsis based on immune response profiling

Sepsis patients could be treated based on their immune system's response to infection, not their symptoms.

18 Jun 2024

National poll highlights bedtime battles and sleep struggles among young children

Many bedtime battles stem from children's after dark worries, suggests a new national poll.

17 Jun 2024

Americans with HIV are living longer. Federal spending isn’t keeping up.

Malcolm Reid recently marked the anniversary of his HIV diagnosis on Facebook. "Diagnosed with HIV 28 years ago, AND TODAY I THRIVE," he wrote in a post in April, which garnered dozens of responses.

17 Jun 2024

AI-driven alerts improve patient care escalation and survival rates in hospitals

Deploying and evaluating a machine learning intervention to improve clinical care and patient outcomes is a key step in moving clinical deterioration models from byte to bedside, according to a June 13 editorial in Critical Care Medicine that comments on a Mount Sinai study published in the same issue.

13 Jun 2024

Many young adults who began vaping as teens can’t shake the habit

G Kumar’s vaping addiction peaked in college at the University of Colorado, when flavored, disposable vapes were taking off.

12 Jun 2024

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

Tokyo Medical and Dental University (TMDU) researchers harness long-read RNA sequencing to decode genetic intricacies and disease links.