Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Stair climbing linked to reduced risk of heart disease, study finds

Forget walking 10,000 steps a day. Taking at least 50 steps climbing stairs each day could significantly slash your risk of heart disease, according to a new study from Tulane University.

29 Sep 2023

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

In some patients, infection with the pandemic virus SARS-CoV-2 can trigger a dangerous immune response in hardened fatty deposits (plaques) lining the heart's largest blood vessels, a new study shows.

28 Sep 2023

SARS-CoV-2 infects coronary vessels, inducing plaque inflammation

SARS-CoV-2, the virus that causes COVID-19, can directly infect the arteries of the heart and cause the fatty plaque inside arteries to become highly inflamed, increasing the risk of heart attack and stroke, according to a study funded by the National Institutes of Health.

28 Sep 2023

New multi-polygenic scores boost coronary heart disease prediction accuracy

Two multi-polygenic scores (muti-PGs) to predict coronary heart disease (CHD).

28 Sep 2023

Hokkaido red wines show promise in boosting vascular function

Researchers find that consuming red wines made from Zweigelt grape varietals cultivated in Hokkaido, Japan, can positively affect vascular and platelet function in healthy adult men, with the 2018 vintage having a more pronounced effect on blood pressure. The study highlights the role of specific polyphenolic profiles in wines for cardiovascular benefits.

21 Sep 2023

Renowned experts comprehensively review how climate change occurs and increases risk of cardiovascular disease

There is already robust evidence that people living with cardiovascular disease are disproportionately affected by poor air quality and extreme temperatures, in large part due to climate change, the greatest threat to human health of the 21st century.

21 Sep 2023

University of Kentucky's cardiovascular scientist recognized for excellence in hypertension research

The University of Kentucky's Vice President for Research and leading cardiovascular scientist is being recognized for her foundational work in the field of hypertension with a prestigious award from the American Heart Association (AHA).

12 Sep 2023

Buck Institute receives $3.5 million federal grant to lead clinical trial of ketone intervention in older adults

The Buck Institute for Research on Aging has received a $3.5 million federal grant to lead the first-ever double-blind, randomized, placebo-controlled clinical trial to understand the effects of ketone ester supplementation on frailty, a condition of vulnerability which develops following age-related decline in multiple physiological systems.

11 Sep 2023

Ketogenic diet shows promise in addressing hormonal imbalance associated with PCOS

Researchers performed a meta-analysis on the impact of ketogenic diets on polycystic ovary syndrome (PCOS).

8 Sep 2023

High blood pressure while lying down linked to increased risk of heart attack, stroke, death

People who had high blood pressure while lying flat on their backs had a higher risk of heart attack, stroke, heart failure or premature death, according to new research to be presented at the American Heart Association's Hypertension Scientific Sessions 2023, to be held Sept. 7-10, 2023, in Boston.

7 Sep 2023

Scientists discover new role for liver tPA in regulating cholesterol levels

Despite advances in treatment for high cholesterol, heart disease remains the leading cause of death in the U.S. Scientists at the Medical College of Wisconsin (MCW) are investigating the role of a form of cholesterol called very-low-density lipoprotein – and their findings may lead to new treatment options in the future.

1 Sep 2023

Amgen presents late-breaking Phase 2 olpasiran data at ESC 2023

Amgen today announced data from the final analysis of the Phase 2 OCEAN(a)-DOSE study of olpasiran, a small interfering RNA (siRNA) during the Late-Breaking Science Session at the European Society of Cardiology (ESC) Annual Meeting being held in Amsterdam. In the off-treatment extension period, olpasiran showed a lasting effect on Lp(a) reduction nearly a year after the last dose.

From AMGEN 1 Sep 2023

Mediterranean diet with a dairy twist shows promise in lowering heart disease risk

An 8-week study found that a Mediterranean diet supplemented with dairy foods altered specific gut bacteria and positively impacted systolic blood pressure in Australians at high risk of cardiovascular disease. The findings suggest that this MedDairy diet could be an effective strategy for reducing cardiovascular risks.

31 Aug 2023

Controlling traditional cardiovascular risk factors can prevent Alzheimer's and other dementias

Cardiovascular disease and dementia frequently occur together in elderly people. Nevertheless, few longitudinal studies have examined how atherosclerosis and its associated risk factors affect brain health from middle age.

30 Aug 2023

Can muvalaplin achieve safe and tolerable plasma concentrations adequate to reduce steady-state Lp(a) levels without modulating plasminogen activity in humans?

Researchers evaluated the tolerability, safety, pharmacodynamics, and pharmacokinetic properties of muvalaplin.

30 Aug 2023

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

The review summarized the involvement of mitochondria in age-related disease progression and highlighted its potential as a therapeutic target of these diseases.

28 Aug 2023

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Researchers described the preclinical profile of JT002, a novel and orally bioavailable small molecule inhibitor of the NLRP3 inflammasome.

24 Aug 2023

Study: Nearly half of heart attack and stroke survivors don't know their LDL cholesterol levels

A 2023 survey from the American Heart Association conducted by The Harris Poll, found that a majority (70%) of heart attack and stroke survivors are unaware that LDL cholesterol is commonly referred to as 'bad cholesterol.'

23 Aug 2023

Texas Heart Institute receives $1.14 million grant to develop first-in-class drug to treat cardiovascular disease

The National Heart, Lung, and Blood Institute (NHLBI) recently awarded The Texas Heart Institute (THI) a two-year, $1.14 million grant to develop a novel, first-in-class drug to treat cardiovascular disease (CVD) as a significant improvement to current treatment regimens - specifically for adverse events arising from atherosclerosis.

22 Aug 2023

Could plant-based diets help treat cardiovascular diseases?

In a recent article published in Nutrients, researchers identified a knowledge gap about the molecular mechanisms by which plant-based diets target cardiovascular diseases (CVDs).

22 Aug 2023

Atherosclerosis News and Research

Further Reading

Stair climbing linked to reduced risk of heart disease, study finds

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

SARS-CoV-2 infects coronary vessels, inducing plaque inflammation

New multi-polygenic scores boost coronary heart disease prediction accuracy

Hokkaido red wines show promise in boosting vascular function

Renowned experts comprehensively review how climate change occurs and increases risk of cardiovascular disease

University of Kentucky's cardiovascular scientist recognized for excellence in hypertension research

Buck Institute receives $3.5 million federal grant to lead clinical trial of ketone intervention in older adults

Ketogenic diet shows promise in addressing hormonal imbalance associated with PCOS

High blood pressure while lying down linked to increased risk of heart attack, stroke, death

Scientists discover new role for liver tPA in regulating cholesterol levels

Amgen presents late-breaking Phase 2 olpasiran data at ESC 2023

Mediterranean diet with a dairy twist shows promise in lowering heart disease risk

Controlling traditional cardiovascular risk factors can prevent Alzheimer's and other dementias

Can muvalaplin achieve safe and tolerable plasma concentrations adequate to reduce steady-state Lp(a) levels without modulating plasminogen activity in humans?

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Study: Nearly half of heart attack and stroke survivors don't know their LDL cholesterol levels

Texas Heart Institute receives $1.14 million grant to develop first-in-class drug to treat cardiovascular disease

Could plant-based diets help treat cardiovascular diseases?

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