Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

CHPA issues statement in response to anti-consumer law on cold and allergy drugs

The Consumer Healthcare Products Association today issued the following statement in response to passage of Senate Bill 437: "Legislation sponsored by Senator Percy Malone and now signed into law places new, onerous burdens on Arkansas families and makes it more difficult for those with common colds and allergies, even basic aches and pains, to get the medications they need. Unfortunately, Senate Bill 437 falls short of the common-sense approach Arkansans expect from their leaders."

28 Mar 2011

Study finds increased risk of VTE during first year of combination oral contraceptive usage

Bayer HealthCare Pharmaceuticals Inc. today announced that interim results from a large, prospective, observational cohort safety study offer insights into the increased risk of venous thromboembolism (VTE), or blood clots, which is a well-established risk in women who use combination oral contraceptives (COCs), also known as "the Pill".

25 Mar 2011

New report shows 2% decrease in anxiolytic and hypnotic sales in Norway

After many years of gradual increase followed by a three-year levelling off period, sales of addictive anxiolytic and hypnotic drugs decreased by just under two per cent in 2010.

24 Mar 2011

Ibuprofen - painkiller toxicity warning

In a recent development, doctors have warned regarding the possibly toxicities of common pain killer Ibuprofen adding that it can lead to a potentially fatal condition which can be triggered, in rare cases, by even a standard dose. The condition in question is called renal tubular acidosis (RTA). The research is published in the Medical Journal of Australia.

21 Mar 2011

MPC urges everyone to program poison center phone number into mobiles

The Maryland Poison Center urges everyone to program the poison center phone number, 1-800-222-1222, into their mobile phones. The number automatically connects callers to a local poison center when it is dialed anywhere in the U.S.

19 Mar 2011

Study evaluates potential national savings from discount generic medication programs

If all eligible patients filled their prescriptions through a $4 generic drug program, the societal savings could amount to nearly $6 billion, according to a University of Pittsburgh Graduate School of Public Health study.

15 Mar 2011

Nanotechnology might provide greater efficacy of medicines for brain disease

Technology has been developed within Top Institute Pharma that helps medicines be absorbed quicker into the blood and thus be more effective. Researcher Hans de Waard, who is associated with the University of Groningen, will obtain his doctorate on this subject on March 11. De Waard: "Many current medicines are not easily dissolved in the digestive tract, which means that they barely reach the bloodstream.

14 Mar 2011

Ibuprofen may protect against development of Parkinson's disease

New research suggests that ibuprofen may offer protection against developing Parkinson's disease, according to one of the largest studies to date investigating the possible benefits of the over-the-counter drug on the disease. The study is published in the March 2, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.

2 Mar 2011

Research: Tanning bed exposure can lead to serious skin problems

Tanning bed exposure can produce more than some tanners may bargain for, especially when they self-diagnose and use the radiation to treat skin eruptions, according to research conducted by the Indiana University School of Medicine Department of Dermatology.

2 Mar 2011

Treat discomfort not fever say the new pediatric guidelines

According to a new report from the American Academy of Pediatrics (AAP), fevers alone are not a cause for intervention in children. Dr. Janice Sullivan, the lead author of the report says, “The focus should be on comfort and not on absolute temperature.” That’s because fever can be help fight illness, by slowing down the reproduction of bacteria and viruses or stimulating the body’s immune response she explains. “That’s a benefit of fever…and may shorten the time that your child remains ill,” she adds.

28 Feb 2011

New research: Fluid retention may explain drugs' risk of strokes and heart attacks

New research shows that medications which have raised safety concerns over heart attack and stroke risks may not have gotten approval from the Food and Drug Administration if the cardiovascular effects of fluid retention had been better understood. Fluid retention may explain the increased risk of heart attacks and strokes of medications such as Vioxx, Bextra, and Avandia.

22 Feb 2011

Efficacy of zinc in common cold - Review of clinical trials

A new study has added to the existing literature that debates the role of zinc in combating the common cold. It suggests that the supplement might modestly reduce cold duration and severity or maybe even prevent it. The report was published as a Cochrane Review.

15 Feb 2011

Genmed announces Suprafen drug registration with Dutch MEB

Genmed Holding Corp. has announced its next generic drug registration. The Company will file it's dossier for the drug Suprafen, otherwise known as Ibuprofen, with the Dutch Medicines Evaluation Board in the coming months. Suprafen is a non-steroidal anti-inflammatory as well as an analgesic.

9 Feb 2011

Phase III study affirms safety and efficacy of Cumberland's Caldolor for post-operative pain

Cumberland Pharmaceuticals Inc. today announced the publication of data affirming the safety and efficacy of Caldolor® (ibuprofen) Injection in treating post-operative pain in hospitalized patients. A Phase III study published in the peer-reviewed journal Pain Practice concluded that IV ibuprofen significantly reduced both morphine use and self-reported pain intensity in patients recovering from abdominal hysterectomy compared to morphine alone.

27 Jan 2011

Painkillers and heart attack risk

A new study has shown that taking certain commonly used painkillers for long periods or in high doses increases the risk of heart attacks or strokes. The study comes from researchers from Bern University and is published in the British Medical Journal.

16 Jan 2011

FDA approves Cumberland's Acetadote Injection

Cumberland Pharmaceuticals today announced that it has received approval from the U.S. Food and Drug Administration for a new formulation of Acetadote Injection, the Company's product used to treat acetaminophen poisoning.

13 Jan 2011

NSAIDs raise risk of heart disease: Study

A new study published online in the British Medical Journal explores the relative safety of non-steroidal anti-inflammatory medications (NSAIDs), commonly used to treat joint and muscle aches and pain and concludes that NSAIDs significantly increase the risk of cardiovascular events in patients who take them regularly.

12 Jan 2011

FDA accepts Merck's JANUMET extended-release formulation NDA for type 2 diabetes

Merck today announced that the New Drug Application (NDA) for the Company's investigational extended-release formulation of JANUMET for type 2 diabetes has been accepted for standard review by the U.S. Food and Drug Administration (FDA). The Company is also moving forward as planned with regulatory filings in countries outside the United States.

12 Jan 2011

Patients who consume painkillers may face cardiovascular risk

The drugs include traditional non-steroidal anti-inflammatory drugs as well as new generation anti-inflammatory drugs, known as COX-2 inhibitors. The researchers say that doctors and patients need to be aware that prescription of any anti-inflammatory drug needs to take cardiovascular risk into account.

12 Jan 2011

New guideline provides evidence-based recommendation for children undergoing tonsillectomy

A multidisciplinary clinical practice guideline, "Tonsillectomy in Children" will be published in the January issue of Otolaryngology-Head and Neck Surgery.

3 Jan 2011