Interferon News and Research

RSS

Investigating the alveolar type II reparative response in COVID-19 pneumonia

Researchers investigated the alveolar type II reparative response in COVID-19 pneumonia.

9 Jun 2023

Shaping the human metabolome: the impact of a ketogenic diet

Researchers explored how the human metabolic fingerprint changes with a ketogenic diet (KD).

6 Jun 2023

Unraveling the complexity of 'Long-COVID' and its impact on breathing

More than a third of COVID-19 patients experience long-lasting symptoms, known as post-COVID-19 condition or long COVID, with breathlessness being a commonly reported symptom. Pulmonary complications, such as fibrosis and thromboembolic disease, require careful assessment, and non-pharmacological interventions like pulmonary rehabilitation can help manage breathlessness.

5 Jun 2023

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Blood-brain barrier breakdown in multiple sclerosis leads to immune cell infiltration into the central nervous system. Antigen presentation at the barrier promotes CD8+ T cell entry, triggering focal breakdown and hindering their invasion.

4 Jun 2023

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

The immunopathology of post-acute sequelae of SARS-CoV-2 infection (PASC).

31 May 2023

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Abdominal obesity increases the risk of severe COVID-19 and mortality due to heightened inflammatory responses, according to a study on Japanese patients and a murine COVID-19 model. Blocking inflammatory cytokines and preventing obesity may improve survival rates.

24 May 2023

Long-term exposure to air pollution associated with higher risk of developing severe COVID-19

A long history of exposure to air pollution is associated with a higher risk of developing severe disease, admission to hospital or an intensive care unit (ICU) and death by COVID‑19 according to a study led by the Barcelona Institute for Global Health (ISGlobal), a research centre supported by the "la Caixa" Foundation.

24 May 2023

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Researchers analyzed data from three SARS-CoV-2 outbreaks among nursing homes in Belgium.

24 May 2023

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

Gut dysfunction and the presence of lipopolysaccharide (LPS) endotoxins contribute to the pathogenesis of Parkinson's disease (PD), leading to neuroinflammation and neurodegeneration. Modulating the gut microbiome and reducing LPS levels may hold potential as treatment strategies for PD.

24 May 2023

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

21 May 2023

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

Research describes the development of a synthetic delivery vector called STxB for mucosal vaccination. It induces mucosal immunity, including resident memory CD8+ T cells and IgA antibodies, against antigens derived from mucosal viruses when administered intranasally in mice.

21 May 2023

Study establishes a mechanistic link between obesity and oral cancer immune escape

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the immune system.

16 May 2023

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Researchers conducted a phase I clinical trial of a personalized mRNA neoantigen vaccine.

12 May 2023

Unlocking the secrets of Omicron: study reveals how unique spike mutations enable enhanced infectivity and resistance to immune barrier

Researchers reported the increased transmissibility of the severe acute respiratory syndrome coronavirus 2.

11 May 2023

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

In a recent article published in the journal Science Immunology, researchers in the United States performed a longitudinal cohort study in a golden hamster model to investigate the sensory-altering mechanisms induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection compared to an influenza A virus (IAV).

11 May 2023

Researchers discover key immune mechanism that helps control inflammatory response to infection

Monash University researchers have discovered a key mechanism in the body's immune system that helps control the inflammatory response to infection. The discovery could help pave the way for more targeted therapies in a range of inflammatory conditions, such as autoimmunity and neuroinflammatory disease.

5 May 2023

Interferon News and Research

Investigating the alveolar type II reparative response in COVID-19 pneumonia

Shaping the human metabolome: the impact of a ketogenic diet

Unraveling the complexity of 'Long-COVID' and its impact on breathing

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Long-term exposure to air pollution associated with higher risk of developing severe COVID-19

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

Study establishes a mechanistic link between obesity and oral cancer immune escape

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Unlocking the secrets of Omicron: study reveals how unique spike mutations enable enhanced infectivity and resistance to immune barrier

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

Researchers discover key immune mechanism that helps control inflammatory response to infection

Unlocking the puzzle: How ACE2 shapes macrophage responses in COVID-19

Study suggests SARS-CoV-2 vaccination in pregnancy induces diverging maternal and infant cord antibody functions

Study sheds light on immune factors responsible for contrasting SARS-CoV-2 outcomes in humans and white-tailed deer

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News