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Blood test for inflammatory and cell senescence biomarkers may help predict cognitive decline

In order to provide the best medical care for newly diagnosed Parkinson's disease (PD) patients, a method of predicting their cognitive and motor progression, beyond using purely clinical parameters, would have major implications for their management.

11 Feb 2020

CD19 CAR NK cell therapy clinical trial shows encouraging results for hematologic cancers

According to results from a Phase I/IIa trial at The University of Texas MD Anderson Cancer Center, treatment with cord blood-derived chimeric antigen receptor natural killer (NK)-cell therapy targeting CD19 resulted in clinical responses in a majority of patients with relapsed or refractory non-Hodgkin's lymphoma and chronic lymphocytic leukemia, with no major toxicities observed.

6 Feb 2020

Discovery of new killer T-cell offers hope of a 'one-size-fits-all' cancer therapy

Researchers at Cardiff University have discovered a new type of killer T-cell that offers hope of a "one-size-fits-all" cancer therapy.

21 Jan 2020

Lab tests reveal that newly discovered T-cell can kill various types of cancer

Scientists have discovered a T-cell receptor that has proven effective in targeting a variety of cancers in mice and in human cells within the lab.

21 Jan 2020

Researchers elucidate role of inflammation resolution sensor in obesity and heart failure

After heart attack injury, several fatty-acid-derived bioactive molecules -- including one called resolvin D1 -- play an essential signaling role to safely clear inflammation and help repair heart muscle. The mechanism of how this resolution occurs is not well-understood.

20 Nov 2019

Blocking a molecule could delay the progression of multiple sclerosis

Over 77,000 Canadians are living with multiple sclerosis, a disease whose causes still remain unknown. Presently, they have no hope for a cure.

14 Nov 2019

New way to measure white blood cell function provides prognostic information about patients with sepsis

Caring for a patient with sepsis requires walking a treatment tightrope. Clinicians must identify the pathogen that is causing a patient's infection, carefully monitor the patient's response to antibiotics and supportive measures and race against the clock to prevent potential organ failure and death.

11 Nov 2019

Study: Regular exercise reduces cholesterol, protects the cardiovascular system

Regular exercise protects the cardiovascular system by reducing risk factors such as cholesterol and blood pressure. "But we believe there are certain risk factors for cardiovascular disease that are not fully understood," says Matthias Nahrendorf, MD, PhD, of the Center for Systems Biology at MGH.

7 Nov 2019

Researchers make new discovery about how exercise protects against cardiovascular disease

A study has identified a molecular link between exercise and inflammation that help to treat cardiovascular disease.

7 Nov 2019

HORIBA’s Yumizen hematology analyzers minimize microscopy slide reviews, improve diagnosis

HORIBA UK Ltd, Medical announces the publication of scientific studies which demonstrate the excellent performance of its new HELO high throughput fully automated haematology platform on body fluid and pathological samples.

From HORIBA Scientific UK 11 Sep 2019

How tuberculosis progresses: genetic factors play a major role

There are almost 1.8 billion people with tuberculosis bacilli in their body, but only about 5% to 15% develop overt infection, usually within 18 months of initial exposure. The reason behind this selective progression has been sought for decades by scientists from a variety of fields.

5 Sep 2019

Large-scale study maps the genetic underpinnings of early TB progression

While the vast majority of the 1.8 billion people infected with the TB bacterium never experience active disease, an estimated 5 to 15 percent do develop full-blown infections--roughly half of them within 18 months of exposure.

4 Sep 2019

Discovery may help identify signs of type 1 diabetes earlier

A new study showed that there are significant differences in the MHC class II antigens on the insulin peptide that is deficient in type 1 diabetes mellitus (T1DM). These determine the response of the T cells to the insulin peptide that causes destruction of insulin.

2 Sep 2019

DNA methylation closely linked to telomere length

Aging is associated with multiple disease conditions. Recently it has been found that many of these illnesses are linked to the length of the telomeres at the ends of every chromosome. Telomere length (TL) is affected by both genetic and epigenetic contributions.

2 Sep 2019

New discovery may help identify type 1 diabetes earlier than is currently possible

Type 1 diabetes, an autoimmune disease that typically emerges before the age of 20, wipes out the body's ability to produce insulin--a hormone that's essential to life. Diagnosis often comes after symptoms arise, at which point the disease has taken hold.

30 Aug 2019

Leukocyte News and Research

Blood test for inflammatory and cell senescence biomarkers may help predict cognitive decline

CD19 CAR NK cell therapy clinical trial shows encouraging results for hematologic cancers

Discovery of new killer T-cell offers hope of a 'one-size-fits-all' cancer therapy

Lab tests reveal that newly discovered T-cell can kill various types of cancer

Researchers elucidate role of inflammation resolution sensor in obesity and heart failure

Blocking a molecule could delay the progression of multiple sclerosis

New way to measure white blood cell function provides prognostic information about patients with sepsis

Study: Regular exercise reduces cholesterol, protects the cardiovascular system

Researchers make new discovery about how exercise protects against cardiovascular disease

HORIBA’s Yumizen hematology analyzers minimize microscopy slide reviews, improve diagnosis

How tuberculosis progresses: genetic factors play a major role

Large-scale study maps the genetic underpinnings of early TB progression

Discovery may help identify signs of type 1 diabetes earlier

DNA methylation closely linked to telomere length

New discovery may help identify type 1 diabetes earlier than is currently possible

New insight into the immune system may help doctors to better fight cancer

Type 1 diabetes linked to gut microbiome and genetic factors

Genetic risk for autoimmunity may be linked to differences in gut microbiome

Sepsis digital alert system could save lives says NHS

Extremely strenuous exercise can overload the heart without increasing cardiac risk

Immunology eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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