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JAX-NYSCF collaborates with GSK to advance human cellular models of neurodegenerative disease

The Jackson Laboratory–New York Stem Cell Foundation Collaborative (JAX-NYSCF) today announced a five-year strategic research collaboration with GSK focused on advancing human cellular models of neurodegenerative disease, including Alzheimer's disease.

17 Feb 2026

Senescent astrocytes identified as key drivers of Alzheimer's progression

Researchers from the NeuroAD group (Neuropathology of Alzheimer's Disease) within the Department of Cell Biology, Genetics and Physiology at the University of Málaga, also affiliated with IBIMA-BIONAND Platform and CIBERNED, have made a pioneering breakthrough in the fight against this disease by identifying astrocytes as a promising cellular target for the development of future therapies.

16 Feb 2026

ARVCF gene deletion leads to abnormalities in reward behavior

The ventral tegmental area (VTA) is a key brain region for dopamine production and the regulation of reward-related behaviors.

13 Feb 2026

Causal gene mapping identifies key drivers of Alzheimer's disease progression

Researchers led by Min Zhang and Dabao Zhang of the University of California, Irvine's Joe C. Wen School of Population & Public Health have created the most detailed maps to date showing how genes causally regulate one another across different types of brain cells affected by Alzheimer's disease.

13 Feb 2026

Exercise-induced activation of neurons mediates improvements in endurance

Exercise does more than strengthen muscles; it also rewires the brain. In a study publishing February 12 in the Cell Press journal Neuron, researchers reveal that the lasting gain in endurance from repeated exercise-such as the ability to run farther and faster over time-involves changes in brain activity that help muscles and hearts to become stronger.

13 Feb 2026

AI system controls brain circuits during social behavior

A male fruit fly in a laboratory chamber extends his wings and vibrates them to produce his species' version of a love song.

12 Feb 2026

Brain circuit links past experiences to appetite control

Our past experiences shape how much we eat and where and what we choose to eat. Using preclinical models, researchers from Mass General Brigham and the Broad Institute of MIT and Harvard have identified brain cells that translate contextual information into appetite control.

12 Feb 2026

FDA-approved anti-seizure drug could help fight Alzheimer's disease

While physicians and scientists have long known Alzheimer's disease involves the buildup of toxic protein fragments in the brain, they have struggled to understand how these harmful fragments are produced.

12 Feb 2026

Visual experience shapes feedback wiring in the brain

Visual experience triggers the formation of a web of neural connections in different brain areas in order to make sense of the world – and in particular, of feedback connections, which send information from higher-level visual centres back to earlier ones.

11 Feb 2026

Neuron lattice structure may guard against neurodegeneration

Brain cells are constantly swallowing material from the fluid that surrounds them - signaling molecules, nutrients, even pieces of their own surfaces - in a process known as endocytosis that is essential for learning, memory and basic neural upkeep.

11 Feb 2026

Shared brainwave biomarker bridges mouse and human fragile X research

Numerous potential treatments for neurological conditions, including autism spectrum disorders, have worked well in lab mice but then disappointed in humans.

11 Feb 2026

Northwestern scientists develop advanced organoid model for human spinal cord injury

Northwestern University scientists have developed the most advanced organoid model for human spinal cord injury to date.

11 Feb 2026

Review links betel nut addiction to cancer, heart disease, and metabolic risks

This review examines the epidemiology, health risks, neurobiological mechanisms, and emerging treatments related to betel nut addiction worldwide. It highlights strong links with oral cancer, cardiometabolic disease, and addiction pathways while noting limited established therapies and the need for coordinated public health strategies.

11 Feb 2026