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Cleveland Clinic and IBM researchers reveal strategy for identifying new immunotherapy targets through AI

Researchers from Cleveland Clinic and IBM have published a strategy for identifying new targets for immunotherapy through artificial intelligence (AI).

23 Jan 2024

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Researchers explored how Death Induced by Survival gene Elimination through the analysis of RNA-induced silencing complex-bound short RNAs in Alzheimer's disease models influences neuronal survival and correlates with neurotoxicity in AD.

22 Jan 2024

Innovative computational tool unearths hidden cancer targets for immunotherapy

An innovative computational tool dubbed "SNAF" may help the research world bring the emerging promise of cancer immunotherapy to a wider range of patients, according to a study published Jan. 17, 2024, in Science Translational Medicine.

17 Jan 2024

Study highlights a potential new strategy to target triple-negative breast cancer

Cleveland Clinic researchers have successfully developed a therapeutic peptide that blocks aggressive cancer cells from multiplying rapidly.

17 Jan 2024

Overcoming adherence challenges: Innovative patch enables controlled drug delivery

A breakthrough in transdermal drug delivery.

17 Jan 2024

CGRP antagonists and dietary changes show promise for migraine treatment

Review in "Medicina" explores advancements in migraine therapy, highlighting the role of CGRP antagonists and dietary interventions like ketogenic and low-glycemic diets in reducing migraine frequency and severity.

17 Jan 2024

Alzheimer's disease found to have five distinct subtypes

Researchers identified five distinct molecular subtypes of Alzheimer's disease using proteomic sequencing, suggesting personalized treatment approaches based on each subtype's unique genetic and pathological characteristics.

10 Jan 2024

Closing the gap: PATROL's approach to overcoming lung cancer diagnostic inequality

A non-invasive, low-cost lung cancer detection platform called PATROL.

9 Jan 2024

Regular exercise key to unlocking whole-body health benefits and reducing disease risk

Study in Cell Metabolism explores how chronic exercise induces tissue adaptations, enhancing cardiometabolic health and reducing disease risk.

8 Jan 2024

New peptide library paves the way for targeting elusive cancer factor MYC

Researchers developed a second-generation NTB bicyclic peptide library, identifying NT-B2R, a peptide that effectively targets MYC, a key factor in most human cancers, demonstrating its potential in inhibiting MYC transcription activities and cancer cell proliferation.

8 Jan 2024

Sesame protein-derived peptides show promise in fighting E. coli and S. aureus

A study in "Nutrients" reveals that sesame protein-derived peptides, Ala-Gly-Gly-Val-Pro-Arg and Ser-Thr-Ile-Arg, show effective antibacterial activity against Escherichia coli and Staphylococcus aureus.

7 Jan 2024

Stapled lipopeptides show promise as broad-spectrum antiviral agents

Compounds that obstruct the "landing gear" of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19, a study published today and led by Dana-Farber Cancer Institute scientists shows.

5 Jan 2024

Researchers develop peptide to target "chaotic" MYC protein in 75% of cancers

Meet MYC, the shapeless protein responsible for making the majority of human cancer cases worse.

4 Jan 2024

Study finds previously unidentified genetic mutation in a small protein provides significant protection against Parkinson’s disease

Researchers explored the effects of a small humanin-like peptide 2 (SHLP2) variant on mitochondrial function.

4 Jan 2024

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

Recent studies by Zampaloni et al. and Pahil et al. published in the journal Nature describe a novel method of inhibiting the growth of Gram-negative bacteria such as Acinetobacter using antibiotics consisting of macrocyclic peptides that target the bacterial protein bridge machinery that transports lipopolysaccharides from the cytoplasm to the outer membrane.

4 Jan 2024

UT Southwestern discovers a two-step screening for heart failure prevention in patients with diabetes

A two-step screening protocol that combines clinical risk assessment with biomarker testing can more effectively identify which patients with Type 2 diabetes need medication to prevent heart failure, according to a study led by UT Southwestern Medical Center researchers.

3 Jan 2024

New method designs high-affinity, orally bioavailable peptides

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy.

28 Dec 2023

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Research delves into the complex roles of neutrophils in inflammatory bowel disease (IBD), exploring their diverse functions and interactions with the gut microbiota and emphasizing the need for targeted therapies based on these insights.

27 Dec 2023

Brazilian researchers create cutting-edge nanoparticle weapon against tuberculosis

A low-cost technology involving nanoparticles loaded with antibiotics and other antimicrobial compounds that can be used in multiple attacks on infections by the bacterium responsible for most cases of tuberculosis has been developed by researchers at São Paulo State University (UNESP) in Brazil and is reported in an article published in the journal Carbohydrate Polymers.

20 Dec 2023

Transgenic carrots producing nisin protein show promise as natural food preservatives

Study explores the production of nisin protein in transgenic carrots, demonstrating its potential as a natural preservative effective against bacterial pathogens in food and juices.

18 Dec 2023

Peptides News and Research

Cleveland Clinic and IBM researchers reveal strategy for identifying new immunotherapy targets through AI

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Innovative computational tool unearths hidden cancer targets for immunotherapy

Study highlights a potential new strategy to target triple-negative breast cancer

Overcoming adherence challenges: Innovative patch enables controlled drug delivery

CGRP antagonists and dietary changes show promise for migraine treatment

Alzheimer's disease found to have five distinct subtypes

Closing the gap: PATROL's approach to overcoming lung cancer diagnostic inequality

Regular exercise key to unlocking whole-body health benefits and reducing disease risk

New peptide library paves the way for targeting elusive cancer factor MYC

Sesame protein-derived peptides show promise in fighting E. coli and S. aureus

Stapled lipopeptides show promise as broad-spectrum antiviral agents

Researchers develop peptide to target "chaotic" MYC protein in 75% of cancers

Study finds previously unidentified genetic mutation in a small protein provides significant protection against Parkinson’s disease

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

UT Southwestern discovers a two-step screening for heart failure prevention in patients with diabetes

New method designs high-affinity, orally bioavailable peptides

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Brazilian researchers create cutting-edge nanoparticle weapon against tuberculosis

Transgenic carrots producing nisin protein show promise as natural food preservatives

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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