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Study highlights link between the induction of fever and antibody levels after COVID-19 mRNA vaccine

mRNA vaccines for COVID-19 generate adverse reactions such as fever and fatigue which are considered normal and are transient in nature.

15 Nov 2022

Study points to a pathogenic role for compromised anti-SARS-CoV-2 responses in cerebrospinal fluid

Researchers used a high throughput systems serology method to compare serum and CSF samples from SARS-CoV-2 infected individuals with and without long COVID symptoms to determine changes in the SARS-CoV-2 humoral immune responses.

15 Nov 2022

Novel drug could help to fight both COVID-19 and cancer

While vaccination can provide life-saving protection against COVID-19, scientists are still searching for ways to treat severe infections, including in people who cannot get vaccinated or in the event that dangerous new strains of the virus arise that could bypass vaccine protection.

14 Nov 2022

Blood samples from healthy individuals have pre-existing anti-SARS-CoV-2 IgGs and IVIg may be an effective therapy for severe COVID-19

A new paper introduces evidence of effective alleviation of disease severity using intravenous immunoglobulin (IVIg).

14 Nov 2022

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers investigated the change in the stability, antigenicity, and protein expression of the SARS-CoV-2 spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein.

14 Nov 2022

The viral fitness and antigenic relationship among Omicron sublineages

Researchers used mouse models and human airway cell cultures to investigate the relative viral replication rates and cross-neutralization against SARS-CoV-2 Omicron sublineages.

14 Nov 2022

How mRNA vaccines work without an added adjuvant

In a recent study published in the Immunity journal, researchers explored the current knowledge of the mechanism employed by messenger ribonucleic acid (mRNA) vaccines to elicit innate immune activation.

13 Nov 2022

Study demonstrates immuno-based strategies to explore the treatment and prevention of COVID-19

Millions have died due to COVID-19 infection, and millions more continue experiencing the chronic condition, Long COVID, which makes discovering practical, accessible, and powerful SARS-CoV-2 preventatives and COVID-19 treatments essential.

11 Nov 2022

Researchers discover new antiviral compounds derived from two Korean native plants

Codonopsis lanceolata, more commonly referred to as "deodeok", is used as a medicinal herb in South Korea.

11 Nov 2022

Mosaic nanoparticles displaying spike protein trimers from different coronaviruses elicits cross-reactive protection

In a recent study under review at the Nature Portfolio journal and currently posted to Research Square* preprint server, researchers developed and assessed the immunogenicity of nanoparticles expressing spike trimers from coronaviruses (CoVs).

10 Nov 2022

Researchers demonstrate that neutralizing antibody titers wane over time in ChAdOx1, BNT162b2 and mRNA-1273 vaccinees

Researchers investigated the neutralization antibody titers and the efficacy of the humoral and cellular immunities in individuals vaccinated with three COVID-19 vaccines.

10 Nov 2022

Does vitamin D reduce COVID-19 severity?

A new study examined published studies for a consistent association between vitamin D levels and coronavirus disease 2019 (COVID-19) severity.

8 Nov 2022

Hybrid immunity from vaccination and Omicron BA.1 or BA.5 breakthrough infections exhibits cross-reactive efficacy against BA.2.75

Researchers recently measured the neutralizing antibody titers against the wild-type strain of SARS-CoV-2 and the SARS-CoV-2 Omicron subvariants in healthcare workers fully vaccinated with three doses of the Comirnaty vaccine who experienced breakthrough Omicron infections.

8 Nov 2022

SARS-CoV-2 activates NLRP3 inflammasome

Researchers assessed the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation.

7 Nov 2022

The Native Antigen Company expands its range of Omicron antigens to include BA.5 variant

The Native Antigen Company (part of LGC Clinical Diagnostics), one of the world’s leading suppliers of reagents that enables research into vaccines and diagnostics for emerging and endemic infectious diseases, today announced the commercial launch of its latest SARS-CoV-2 antigens for the newly designated Omicron BA.5 variant.

From The Native Antigen Company 7 Nov 2022

Spike Protein News and Research

Study highlights link between the induction of fever and antibody levels after COVID-19 mRNA vaccine

Study points to a pathogenic role for compromised anti-SARS-CoV-2 responses in cerebrospinal fluid

Novel drug could help to fight both COVID-19 and cancer

Blood samples from healthy individuals have pre-existing anti-SARS-CoV-2 IgGs and IVIg may be an effective therapy for severe COVID-19

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

The viral fitness and antigenic relationship among Omicron sublineages

How mRNA vaccines work without an added adjuvant

Study demonstrates immuno-based strategies to explore the treatment and prevention of COVID-19

Researchers discover new antiviral compounds derived from two Korean native plants

Mosaic nanoparticles displaying spike protein trimers from different coronaviruses elicits cross-reactive protection

Researchers demonstrate that neutralizing antibody titers wane over time in ChAdOx1, BNT162b2 and mRNA-1273 vaccinees

Does vitamin D reduce COVID-19 severity?

Hybrid immunity from vaccination and Omicron BA.1 or BA.5 breakthrough infections exhibits cross-reactive efficacy against BA.2.75

SARS-CoV-2 activates NLRP3 inflammasome

The Native Antigen Company expands its range of Omicron antigens to include BA.5 variant

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Vimentin is an important co-receptor for SARS-CoV-2 infection

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

People who had COVID-19 are more vulnerable to developing neurological symptoms

New research suggests booster dose of Novavax NVX-CoV2373 vaccine is effective against SARS-CoV-2 Omicron subvariants

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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