Tau Protein News and Research

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Tau proteins are microtubule-associated proteins found in neurons in the brain.

Study explains link between poor sleep and Alzheimer's disease

A good night's sleep refreshes body and mind, but a poor night's sleep can do just the opposite. A study from Washington University School of Medicine in St. Louis, Radboud University Medical Centre in the Netherlands, and Stanford University has shown that disrupting just one night of sleep in healthy, middle-aged adults causes an increase in amyloid beta, a brain protein associated with Alzheimer's disease.

10 Jul 2017

Scientists shed new light on how tau protein transitions from liquid state to solid tangles

While much about Alzheimer's disease remains a mystery, scientists do know that part of the disease's progression involves a normal protein called tau, aggregating to form ropelike inclusions within brain cells that eventually strangle the neurons.

6 Jul 2017

Scientists provide detailed view of tau protein structures found in Alzheimer's disease

New research by scientists at the MRC Laboratory of Molecular Biology in the United Kingdom and Indiana University School of Medicine gives the most detailed view yet of tau protein structures found in Alzheimer's disease.

6 Jul 2017

Alzheimer’s disease specific brain deposits photographed for the first time in vivid detail

Scientists from the Britain's Medical Research Council Laboratory of Molecular Biology have for the first time, clearly pictured what the deposits typically seen in a person with Alzheimer’s disease look like. This is a breakthrough in neurodegenerative diseases. The latest study showing the structure of tau protein was published in the journal Nature.

5 Jul 2017

Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

The design of tailored peptide-polymer conjugates as drug-specific formulation additives offers access to next generation precision additives that can render problematic small organic drugs water-soluble and improve bioavailability.

30 Jun 2017

Anti-seizure drug could have beneficial effect in patients with mild Alzheimer's disease

In the last decade, mounting evidence has linked seizure-like activity in the brain to some of the cognitive decline seen in patients with Alzheimer's disease.

23 Jun 2017

Researchers measure spread of tau protein in the brains of Alzheimer’s patients

In a new study presented in Molecular Psychiatry, researchers at Karolinska Institutet have measured how deposits of the pathological protein tau spread through the brain over the course of Alzheimer's disease.

16 May 2017

Scientists find new way to measure tau protein levels in the blood

Damaging tangles of the protein tau dot the brains of people with Alzheimer's and many other neurodegenerative diseases, including chronic traumatic encephalopathy, which plagues professional boxers and football players.

20 Apr 2017

New humanized model enables better characterization of Alzheimer's pathology

Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.

24 Feb 2017

Researchers identify link between neuronal proteins and frontotemporal lobar degeneration

Frontotemporal lobar degeneration is a type of dementia characterized by personality changes, language dysfunction, and abnormal behavior. It has an earlier onset than Alzheimer's disease, and is associated with a buildup of the tau protein in affected nerve cells (neurons).

13 Feb 2017

Designer compound may be effective tool for tackling tau-related disorders

In a study of mice and monkeys, National Institutes of Health funded researchers showed that they could prevent and reverse some of the brain injury caused by the toxic form of a protein called tau.

8 Feb 2017

Synthetic molecule appears to reverse Alzheimer's-related neurological damage

Under ordinary circumstances, the protein tau contributes to the normal, healthy functioning of brain neurons. In some people, though, it collects into toxic tangles that damage brain cells.

25 Jan 2017

Tau pathology underlies deterioration of spatial cognition in Alzheimer's disease

Columbia University Medical Center researchers have discovered that the spatial disorientation that leads to wandering in many Alzheimer's disease patients is caused by the accumulation of tau protein in navigational nerve cells in the brain.

20 Jan 2017

Scientists discover gene that may open new door to developing treatments for Alzheimer's disease

Scientists at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have identified a gene that may provide a new starting point for developing treatments for Alzheimer's disease (AD).

11 Jan 2017

Penn study finds evidence of AD neuropathology in post-mortem brains of LBD patients

Patients who had a diagnosis of Parkinson's disease (PD) with dementia (PDD) or dementia with Lewy bodies (DLB) and had higher levels of Alzheimer's disease (AD) pathology in their donated post-mortem brains also had more severe symptoms of these Lewy body diseases (LBD) during their lives, compared to those whose brains had less AD pathology, according to research from the Perelman School of Medicine at the University of Pennsylvania.

6 Jan 2017

Tau biomarker could lead to early identification of Alzheimer's disease pathology

A discovery of high relevance in medical research will be published in Volume 55, number 4 of December 2016 of the prestigious "Journal of Alzheimer's Disease (JAD)", entitled "Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer's Disease".

22 Dec 2016

Study finds way to detect early signs of AD by looking at retina of patients' eyes

A new study from The University of Texas Medical Branch at Galveston offers important insight into how Alzheimer's disease begins within the brain.

18 Nov 2016

Llama antibodies can detect cerebral lesions that characterize Alzheimer's disease

The major challenge facing physicians treating Alzheimer's is the ability to detect markers of the disease as early as possible. These markers, located in the brain, are difficult to access, hampering diagnosis.

4 Nov 2016

Distinct structures of tau protein aggregates may help determine type of dementia, study shows

The distinct structures of toxic protein aggregates that form in degenerating brains determine which type of dementia will occur, which regions of brain will be affected, and how quickly the disease will spread, according to a study from the Peter O'Donnell Jr. Brain Institute.

31 Oct 2016

New study unravels cause of cognitive loss in tauopathy disorders

Tauopathies are a group of neurodegenerative disorders, including Alzheimer's disease that are characterized by the deposition of aggregates of the tau protein inside brain cells.

13 Oct 2016

Tau Protein News and Research

Further Reading

Study explains link between poor sleep and Alzheimer's disease

Scientists shed new light on how tau protein transitions from liquid state to solid tangles

Scientists provide detailed view of tau protein structures found in Alzheimer's disease

Alzheimer’s disease specific brain deposits photographed for the first time in vivid detail

Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

Anti-seizure drug could have beneficial effect in patients with mild Alzheimer's disease

Researchers measure spread of tau protein in the brains of Alzheimer’s patients

Scientists find new way to measure tau protein levels in the blood

New humanized model enables better characterization of Alzheimer's pathology

Researchers identify link between neuronal proteins and frontotemporal lobar degeneration

Designer compound may be effective tool for tackling tau-related disorders

Synthetic molecule appears to reverse Alzheimer's-related neurological damage

Tau pathology underlies deterioration of spatial cognition in Alzheimer's disease

Scientists discover gene that may open new door to developing treatments for Alzheimer's disease

Penn study finds evidence of AD neuropathology in post-mortem brains of LBD patients

Tau biomarker could lead to early identification of Alzheimer's disease pathology

Study finds way to detect early signs of AD by looking at retina of patients' eyes

Llama antibodies can detect cerebral lesions that characterize Alzheimer's disease

Distinct structures of tau protein aggregates may help determine type of dementia, study shows

New study unravels cause of cognitive loss in tauopathy disorders

Industry Focus eBook - Life Science Microscopy (3rd Edition) eBook

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Industry focus eBook - The Digital Laboratory (4th edition)

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (3rd Edition)

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