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FDA approves first companion diagnostic that uses liquid biopsy and NGS technology

Today, the U.S. Food and Drug Administration approved the first liquid biopsy companion diagnostic that also uses next-generation sequencing (NGS) technology to identify patients with specific types of mutations of the epidermal growth factor receptor (EGFR) gene in a deadly form of metastatic non-small cell lung cancer (NSCLC).

7 Aug 2020

UTHSC professor recognized for contributions to pioneering cancer genomic research

Neil Hayes, MD, MS, MPH, division chief of Hematology and Oncology at the University of Tennessee Health Science Center, is among recipients of the 2020 Team Science Awards from the American Association for Cancer Research for his contributions to developing The Cancer Genome Atlas, a groundbreaking multisite project to understand cancer at its molecular level through genome sequencing and extensive data analysis.

7 Aug 2020

NSD2 enzyme protects against cellular senescence

Researchers from Kumamoto University in Japan have used comprehensive genetic analysis to find that the enzyme NSD2, which is known to regulate the actions of many genes, also works to block cell aging.

7 Aug 2020

Researchers develop a deep learning-based algorithm for predicting sites of DNA methylation

A team of researchers from New Jersey Institute of Technology and Children's Hospital of Philadelphia have developed an algorithm through machine learning that helps predict sites of DNA methylation - a process that can change the activity of DNA without changing its overall structure - and could identify disease-causing mechanisms that would otherwise be missed by conventional screening methods.

6 Aug 2020

Surgical delay does not lower overall survival of women with early-stage breast cancer

A new breast cancer study brings reassuring findings for women with early-stage breast cancer who were forced to delay their cancer operations because of the Coronavirus Disease 2019 (COVID-19) pandemic.

6 Aug 2020

Specific gene impairment may also protect people with Down syndrome

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered that a set of genes with decreased expression in individuals with Down syndrome may lead to clinical abnormalities in this population, such as poor muscle development and heart valve problems.

6 Aug 2020

Human encroachment into forest land caused bat CoV spillover and COVID-19 emergence

A new study published on the preprint server medRxiv in August 2020 discusses the root causes underlying the emergence of such infectious diseases following their crossover of the line separating animal viruses from human. This initial event is of enormous significance.

6 Aug 2020

New medical imaging resource center at UChicago will help tackle COVID-19 pandemic

A new center hosted at the University of Chicago -- co-led by the largest medical imaging professional organizations in the country -- will help tackle the ongoing COVID-19 pandemic by curating a massive database of medical images to help better understand and treat the disease.

5 Aug 2020

Study provides new insights into how ovarian cancer grows and evolves

In a paper published in the journal Cancer Research, professor Levi Waldron, post-doctoral fellow Ludwig Geistlinger, and colleagues at the Institute for Implementation Science in Population Health at the CUNY Graduate School of Public Health and Health Policy) provide new insights into how ovarian cancer grows and evolves within a person.

5 Aug 2020

Horizon Discovery introduces single cell RNAseq-linked CRISPR screening service

Horizon Discovery Group plc, today announced the addition of single cell RNAseq-linked pooled CRISPR screening to its CRISPR screening services portfolio.

From Revvity 5 Aug 2020

Study: Inhibition of TLK protein stimulates the innate immune system

Tousled-like kinases (TLKs) are a potential therapeutic target for cancer treatment due to their central role in DNA repair and replication.

5 Aug 2020

Genetic variation influencing chromatin states associated with neuropsychiatric disorders

A new study led by NorthShore University HealthSystem and the University of Chicago took a novel approach to identifying SNPs influencing the risk of neuropsychiatric disorders like schizophrenia, bipolar and major depressive disorder, the institutions announced today.

4 Aug 2020

Study identifies impact of gene mutations on severity of myelodysplastic syndrome

The Myelodysplastic Syndromes Group of Josep Carreras Leukaemia Research Institute, led by Dr. Francesc Solé, has participated in the first international study that confirms that having two mutated copies of the TP53 gene, as opposed to a single mutated copy, is associated with a worse prognosis in patients diagnosed with myelodysplastic syndrome (MDS).

4 Aug 2020

Genomic News and Research

FDA approves first companion diagnostic that uses liquid biopsy and NGS technology

UTHSC professor recognized for contributions to pioneering cancer genomic research

NSD2 enzyme protects against cellular senescence

Researchers develop a deep learning-based algorithm for predicting sites of DNA methylation

Surgical delay does not lower overall survival of women with early-stage breast cancer

Specific gene impairment may also protect people with Down syndrome

Human encroachment into forest land caused bat CoV spillover and COVID-19 emergence

New medical imaging resource center at UChicago will help tackle COVID-19 pandemic

Study provides new insights into how ovarian cancer grows and evolves

Horizon Discovery introduces single cell RNAseq-linked CRISPR screening service

Study: Inhibition of TLK protein stimulates the innate immune system

Genetic variation influencing chromatin states associated with neuropsychiatric disorders

Study identifies impact of gene mutations on severity of myelodysplastic syndrome

CNIO and HKUST researchers identify how some gliomas acquire chemoresistance

NIH-funded project to develop AI-based system to help doctors cure cancer

Researchers discover treatment for severe auto inflammatory syndrome

Normal DNA repair process can lead to mutations in cancer

Regulatory mechanisms involved in brain development are same for insects and mammals

Researchers develop scalable strategy to find novel molecular glue degraders

Study solves long-held controversy over two popular bird species

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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