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Study offers localized treatment direction for a cause of Crohn's disease

People with Crohn's disease are typically treated with powerful anti-inflammatory medications that act throughout their body, not just in their digestive tract, creating the potential for unintended, and often serious, side effects.

7 Apr 2021

Researchers discover a gene family strongly implicated in the development of liver cancer

In a comprehensive analysis of human gene activation data, researchers from the Centenary Institute have discovered that the dipeptidyl peptidase-4 (DPP4) gene family is strongly implicated in the development of human hepatocellular carcinoma (HCC), the most common type of primary liver cancer.

7 Apr 2021

New grant to Harvard Medical School is boosting efforts to understand and combat rare cancers

Curing cancer has been the dream of countless doctors and researchers over the decades. Yet some types of cancer, whether because they affect relatively few people or lack influential advocates, receive less attention and funding than others.

7 Apr 2021

Researchers evaluate new drug for spinal muscular atrophy in a broader spectrum of patients

The rarity of spinal muscular atrophy (SMA) means that promising new treatments may be tested in only a limited spectrum of patients before approval. Investigators evaluated a newly approved drug, onasemnogene abeparvovec, in a broader spectrum of patients in order to obtain expanded data on its side effects profile.

6 Apr 2021

Devastating liver disease itching turns out to have a surprising cause

A devastating itching of the skin driven by severe liver disease turns out to have a surprising cause. Its discovery points toward possible new therapies for itching, and shows that the outer layer of the skin is so much more than insulation.

5 Apr 2021

Study paves way for effective monitoring of chemotherapeutic drug level in cancer patients

Cancer is the world's second deadliest disease which contributes towards the fatality of over 10 million people per year.

3 Apr 2021

Scientists identify nine potential new COVID-19 treatments

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has identified nine potential new COVID-19 treatments, including three that are already approved by the Food and Drug Administration (FDA) for treating other diseases.

2 Apr 2021

Muscle strength and mass may predict hospital stay duration in COVID-19 patients

Researchers found that COVID-19 patients with good muscle strength and higher muscle mass had a shorter stay in the hospital.

2 Apr 2021

Unique approach to heart-liver transplant offers new hope for highly sensitized patients

All too often, patients with high levels of antibodies face major challenges getting a transplant. These highly sensitized patients have a much higher risk of death while waiting for suitable organs they are less likely to reject.

1 Apr 2021

Researchers identify protein that interferes with the body's ability to get rid of 'bad' cholesterol

A team of researchers at the University of Alberta has uncovered a long-sought link in the battle to control cholesterol and heart disease.

1 Apr 2021

COVID-19 patients discharged from hospital have increased rates of multiorgan dysfunction

People discharged from hospital after covid-19 appear to have increased rates of organ damage (“multiorgan dysfunction”) compared with similar individuals in the general population, finds a study published by The BMJ today.

1 Apr 2021

Researchers develop a recombinant SARS-CoV-2 receptor-binding domain trimer vaccine candidate

New research deals with the development of RBD trimer as a potent target for SARS-CoV-2 subunit vaccines. This study revealed the development of a trimeric RBD subunit vaccine candidate that could induce strong humoral and cellular immune responses in nonhuman primates (NHPs), namely, rhesus macaques.

1 Apr 2021

Researchers reveal pathways that lead to the development of tissue-resident lymphocytes

Researchers from the University of Science and Technology of China) of the Chinese Academy of Science (CAS), teamed up with scientists from Aix Marseille University, discovered that hematopoietic progenitors possessed the differentiation potential to type 1 innate lymphoid cells in adult liver, and dissected the regulation mechanisms of such cell differentiation, revealing the pathways that lead to the development of tissue-resident lymphocytes.

31 Mar 2021

Obesity and ethnicity identified as key risk factors for SARS-CoV-2 exposure in UK

The risk factors for severe COVID-19 have been established on the basis of observational studies. However, SARS-CoV-2 continues to cause thousands of COVID-19 cases all over the world, and the risk factors are unclear. A new study deals with this aspect of the pandemic.

31 Mar 2021

Research consortium identifies cell stress mechanisms for chronic inflammatory liver disease

Primary sclerosing cholangitis (PSC) is a rare, chronic, inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched.

30 Mar 2021

Restricting excessive consumption of added sugars may reduce NAFLD risk in children

A review of more than 20 studies by researchers at Arizona State University and the Translational Genomics Research Institute, an affiliate of City of Hope, suggests that nonalcoholic fatty-liver disease (NAFLD) is a growing dietary problem for children across the globe.

29 Mar 2021

Study shows safety, efficacy of percutaneous thermal ablation for treating metastatic gynecologic cancers

A new study by researchers at the UCLA Jonsson Comprehensive Cancer Center found using percutaneous image guided needle based thermal ablation -- the precise application of extreme heat or cold to a tumor using sophisticated ultrasound, CT or MRI in a single outpatient session -- is a safe and effective adjunctive therapy for the local control of metastatic gynecologic cancers throughout lungs, liver, soft tissues in the abdomen and pelvis and bones in patients with advanced localized cancers unresponsive to systemic therapy.

29 Mar 2021

Advanced technology provides a fine-grained picture of lung pathology in COVID-19

A team led by investigators at Weill Cornell Medicine and NewYork-Presbyterian has used advanced technology and analytics to map, at single-cell resolution, the cellular landscape of diseased lung tissue in severe COVID-19 and other infectious lung diseases.

29 Mar 2021

Patients diagnosed with incurable cancer need early access to supportive palliative care

So far, there has been little research into supportive care needs in patients with newly diagnosed incurable cancer and as their disease progresses.

26 Mar 2021

Surgery is viable in more pancreatic cancer cases than commonly thought, study shows

Patients with stage II pancreatic cancer who are treated with chemotherapy followed by resection (an operation that removes the cancerous part of the organ, structure or tissue) live nearly twice as long as patients who receive only chemotherapy, according to a new Journal of the American College of Surgeons study published online in advance of print.

26 Mar 2021

Liver News and Research

Study offers localized treatment direction for a cause of Crohn's disease

Researchers discover a gene family strongly implicated in the development of liver cancer

New grant to Harvard Medical School is boosting efforts to understand and combat rare cancers

Researchers evaluate new drug for spinal muscular atrophy in a broader spectrum of patients

Devastating liver disease itching turns out to have a surprising cause

Study paves way for effective monitoring of chemotherapeutic drug level in cancer patients

Scientists identify nine potential new COVID-19 treatments

Muscle strength and mass may predict hospital stay duration in COVID-19 patients

Unique approach to heart-liver transplant offers new hope for highly sensitized patients

Researchers identify protein that interferes with the body's ability to get rid of 'bad' cholesterol

COVID-19 patients discharged from hospital have increased rates of multiorgan dysfunction

Researchers develop a recombinant SARS-CoV-2 receptor-binding domain trimer vaccine candidate

Researchers reveal pathways that lead to the development of tissue-resident lymphocytes

Obesity and ethnicity identified as key risk factors for SARS-CoV-2 exposure in UK

Research consortium identifies cell stress mechanisms for chronic inflammatory liver disease

Restricting excessive consumption of added sugars may reduce NAFLD risk in children

Study shows safety, efficacy of percutaneous thermal ablation for treating metastatic gynecologic cancers

Advanced technology provides a fine-grained picture of lung pathology in COVID-19

Patients diagnosed with incurable cancer need early access to supportive palliative care

Surgery is viable in more pancreatic cancer cases than commonly thought, study shows

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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