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NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

More than 60 percent of investigational drugs fail in human clinical trials due to a lack of effectiveness, despite promising pre-clinical studies using cell and animal research models.

13 Sep 2017

'Metabolically healthy obese' have increased risk of cardiovascular disease events, study shows

Clinicians are being warned not to ignore the increased cardiovascular health risks of those who are classed as either 'healthy obese' or deemed to be 'normal weight' but have metabolic abnormalities such as diabetes.

11 Sep 2017

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

Adding taselisib to letrozole before surgery significantly improved outcomes for patients with early breast cancer that was both estrogen receptor positive and HER2-negative (ER+/HER2-) according to results of the LORELEI trial, presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Research shows new method for rapidly producing antimalarial drug at industrial scale

Compared to smallpox or typhoid, malaria is proving one of the most challenging human diseases to eradicate - and so remains a real and constant danger to nearly half the world's population.

7 Sep 2017

Sodium channels play important role in keeping tiny lung capillaries from leaking, worsening pneumonia

Sodium channels in the cells that line the tiny capillaries in our lungs play an important role in keeping those capillaries from leaking and potentially worsening conditions like pneumonia, scientists report.

6 Sep 2017

Research provides new insights into secret life of bacteria

Bacterial infections are the number one cause of death in hospital patients in the United States, and antibiotic-resistant bacteria are on the rise, causing tens of thousands of deaths every year.

6 Sep 2017

Antibiotics may kill bacteria differently in vitro vs in vivo

Understanding exactly how antibiotics work (or don’t work) is crucial for developing alternative treatment strategies, not only to target new “superbugs,” but also to make existing drugs more effective against their targets.

5 Sep 2017

Leica Microsystems receives first FDA clearance for its FL560 fluorescence microscope filter

Leica Microsystems is the first company in the US receiving FDA 510(k) clearance for the visualization of cerebrovascular blood flow in conjunction with fluorescein.

From Leica Microsystems GmbH 1 Sep 2017

Common heart disease medication may help treat pulmonary arterial hypertension

A team of Cleveland Clinic researchers found that a common heart disease medication, beta blockers, may help treat pulmonary arterial hypertension (PAH), a debilitating lung disease.

31 Aug 2017

Link found between fetal genes and risk of preeclampsia in mother

For the first time, a relationship has been found between fetal genes and the risk of preeclampsia in the mother.

31 Aug 2017

New trial examines whether compound given before and after bypass surgery mitigates cognitive deficits

University of Arizona researchers are collaborating on a Phase 2 trial to determine whether a particular peptide administered before and after coronary bypass surgery mitigates or even reverses cognitive deficits thought to be connected to the procedure.

31 Aug 2017

Study shows metabolic, cardiovascular consequences of untreated sleep apnea

Sleep apnea, left untreated for even a few days, can increase blood sugar and fat levels, stress hormones and blood pressure, according to a new study of sleeping subjects.

31 Aug 2017

'Open gym' format reduces cardiac rehabilitation wait times, study reports

Changing from scheduled appointments to an "open gym" format can reduce waiting times for cardiac rehabilitation, reports a study in the September/October issue of Journal of Cardiopulmonary Rehabilitation and Prevention.

30 Aug 2017

Placenta-on-a-chip device mimics microenvironment of malaria in the womb to develop treatments

Malaria, one of the most severe public health problems, affected 212 million people worldwide in 2015. This life-threatening disease is caused by parasites that are transmitted to humans through the bites of infected female Anopheles mosquitoes.

29 Aug 2017

IBS scientists uncover key regulator of normal as well as pathological angiogenesis

New blood vessels branch out of preexisting ones is via a process called angiogenesis. Although this is essential for survival, development and wound healing, on the flip side, it also feeds and progresses malignant tumors, as well as other diseases.

29 Aug 2017

Study: People with shorter LTL have more benefits on cognition following lifestyle intervention

Is telomere length associated with the cognitive response to a lifestyle intervention? Supporting evidence from the FINGER trial.

29 Aug 2017

LSU Health New Orleans to receive $735,000 for improving heart attack recovery

LSU Health New Orleans will receive $735,000 over two years to study the effectiveness of the first patented drug-eluting guidewire in preventing a complication that can occur following treatment of heart attacks with angioplasty.

28 Aug 2017

Study shows previously unknown dimension of lymphangiogenesis during worm infection

Lymph nodes are small, kidney-shaped organs found throughout the body. Full of immune cells, their function is to clear out foreign objects and support the immune system.

28 Aug 2017

FDA issues warning letter to US Stem Cell Clinic for significant deviations

The U.S. Food and Drug Administration today posted a warning letter issued to US Stem Cell Clinic of Sunrise, Florida, and its Chief Scientific Officer Kristin Comella for marketing stem cell products without FDA approval and for significant deviations from current good manufacturing practice requirements, including some that could impact the sterility of their products, putting patients at risk.

28 Aug 2017

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

Rivaroxaban plus aspirin improves survival and reduces stroke and heart attack in patients with stable coronary or peripheral artery disease, according to late-breaking results from the COMPASS trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in the NEJM.

28 Aug 2017

Vascular News and Research

NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

'Metabolically healthy obese' have increased risk of cardiovascular disease events, study shows

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

Research shows new method for rapidly producing antimalarial drug at industrial scale

Sodium channels play important role in keeping tiny lung capillaries from leaking, worsening pneumonia

Research provides new insights into secret life of bacteria

Antibiotics may kill bacteria differently in vitro vs in vivo

Leica Microsystems receives first FDA clearance for its FL560 fluorescence microscope filter

Common heart disease medication may help treat pulmonary arterial hypertension

Link found between fetal genes and risk of preeclampsia in mother

New trial examines whether compound given before and after bypass surgery mitigates cognitive deficits

Study shows metabolic, cardiovascular consequences of untreated sleep apnea

'Open gym' format reduces cardiac rehabilitation wait times, study reports

Placenta-on-a-chip device mimics microenvironment of malaria in the womb to develop treatments

IBS scientists uncover key regulator of normal as well as pathological angiogenesis

Study: People with shorter LTL have more benefits on cognition following lifestyle intervention

LSU Health New Orleans to receive $735,000 for improving heart attack recovery

Study shows previously unknown dimension of lymphangiogenesis during worm infection

FDA issues warning letter to US Stem Cell Clinic for significant deviations

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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