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KiNet web portal enhances study of kinase functions in cellular signaling pathways

Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. These interactions play a vital role in modulating complex signaling pathways that control various cellular processes, such as cell growth, differentiation, and response to environmental stimuli.

4 Oct 2024

Stem cell transplants show promise for macular hole repair in monkeys

Human stem cell transplants successfully repaired macular holes in a monkey model, researchers report October 3rd in the journal Stem Cell Reports. After transplantation, the macular holes were closed by continuous filling of the space with retinal tissue.

3 Oct 2024

Unlocking the mystery of the fruit fly's internal compass

For decades, researchers had a theory about how an animal's brain keeps track of where it is relative to its surroundings without outside cues – like how we know where we are, even with our eyes closed

3 Oct 2024

Houston Methodist researchers join national consortium to develop herpesvirus vaccine

Houston Methodist researchers will be part of a national consortium funded by an up to $49 million award from the U.S. Government's Advanced Research Projects Agency for Health (ARPA-H) to develop a vaccine against two of the most common and destructive strains of herpesviruses that latently infect a majority of Americans and can lead to acute infections, multiple forms of cancer, autoimmune disease and birth defects.

3 Oct 2024

International experts to gather for ALS symposium in Chicago

The 2024 Les Turner Symposium on ALS will be held on Monday, Nov. 4 in Chicago. Hosted by the Les Turner ALS Foundation and the Les Turner ALS Center at Northwestern Medicine, this event will assemble internationally-renowned ALS researchers, clinicians, advocates, and people living with ALS to discuss the latest research and perspectives on the disease.

3 Oct 2024

Innovative blood test for lung cancer offers faster and more sensitive diagnosis

A new way of diagnosing lung cancer with a blood draw is 10 times faster and 14 times more sensitive than earlier methods, according to University of Michigan researchers.

3 Oct 2024

Researchers boost natural defenses to fight cataracts and delay the need for surgery

Researchers have reviewed strategies to increase glutathione levels in the eye lens, focusing on endogenous molecular mechanisms to prevent cataracts by countering oxidative stress.

3 Oct 2024

Insights into bacterial coexistence in fungal cells

An organism as a tenant in another - in biology, this often works quite well. ETH researchers have now shed light on how such a partnership of a cell in a cell can establish.

3 Oct 2024

Wake Forest University receives NIH grant to investigate medical misinformation

Researchers at Wake Forest University School of Medicine have received a five-year, $3.4 million grant from the National Institute on Aging, part of the National Institutes of Health, to study medical misinformation.

3 Oct 2024

New method harnesses light to activate neurons in the brain

University of Rochester researchers have demonstrated a noninvasive method using BL-OG, or bioluminescent optogenetics, that harnesses light to activate neurons in the brain.

3 Oct 2024

Non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma

A new study led by investigators from the UCLA Health Jonsson Comprehensive Cancer Center has demonstrated a new, non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma, the most common form of kidney cancer.

3 Oct 2024

Researchers make breakthrough in Alzheimer's disease drug development

An international team of researchers led by Lancaster University have made a promising breakthrough in the development of drugs to treat Alzheimer's Disease.

3 Oct 2024

New guidelines for conducting systematic reviews of animal and cell studies

A new publication in Nature Reviews Methods Primers provides essential guidance for conducting rigorous systematic reviews on studies with animals and cells.

3 Oct 2024

Antioxidant-rich diet could help lower risk of infertility in women, new study suggests

The study reveals that increased antioxidant consumption may protect against infertility in women, addressing oxidative stress in reproductive disorders.

3 Oct 2024

Doctors urging conference boycotts over abortion bans face uphill battle

Soon after the U.S. Supreme Court issued its Roe v. Wade abortion ruling in 1973, Laura Esserman used her high school graduation speech to urge her classmates to vote for the Equal Rights Amendment to expand women's access to property, divorce, and abortion.

3 Oct 2024

Florida breast cancer foundation funds two UCF projects to combat breast cancer

As Breast Cancer Awareness Month begins, two College of Medicine cancer researchers have received statewide grants to support their innovative projects to fight a disease that strikes one in eight American women.

3 Oct 2024

New pathway linking neuron selectivity to cognitive disorders uncovered

Neuroscientists from Johns Hopkins Medicine say they have determined how a brain cell surface molecule shapes the way certain neurons behave.

3 Oct 2024

The threat of serous uterine cancer: A new perspective

Most uterine cancers have excellent five-year survival rates – up to 95% for localized cancer. Serous uterine cancer is an exception, with five-year survival rates of 35% to 50% for stage 1 or 2 cancer.

3 Oct 2024

Key RNA pathway controlling DNA packaging and cancer progression

Inside every cell, inside every nucleus, your continued existence depends on an incredibly complicated dance. Proteins are constantly wrapping and unwrapping DNA, and even minor missteps can lead to cancer.

3 Oct 2024

The impact of KRAS mutations on pancreatic cancer progression and survival

A common mutation in the KRAS gene is associated with improved overall survival in pancreatic ductal adenocarcinoma (PDAC) compared with other variants, in part because the mutation appears to lead to less invasiveness and weaker biological activity, according to a multicenter study conducted at Weill Cornell Medicine, NewYork-Presbyterian, Memorial Sloan Kettering Cancer Center, and other institutions.

3 Oct 2024