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Likelihood of IVF success increases if 18 to 20 eggs are collected

The likelihood of childbirth after in vitro fertilization treatment increases if 18 to 20 eggs are stimulated to mature in a woman's ovaries, a dissertation at Sahlgrenska Academy, Sweden, shows. That is more eggs than the number aimed at in today's IVF treatments.

3 Sep 2018

A genetic signal-transmission system for the gut microbiome

More than 1,000 species of bacteria have been identified in the human gut, and understanding this incredibly diverse "microbiome" that can greatly impact health and disease is a hot topic in scientific research.

31 Aug 2018

Celmatix and Ferring announce genomics collaboration aimed at uncovering new insights into ovarian biology

Ferring Pharmaceuticals and Celmatix today announced an ambitious genomics collaboration aimed at uncovering new insights into ovarian biology and accelerating the development of personalized interventions in reproductive medicine and women's health.

30 Aug 2018

FDA accepts Bristol-Myers Squibb’s application for Sprycel for treating pediatric leukemia

Bristol-Myers Squibb Company today announced that the U.S. Food and Drug Administration accepted its supplemental Biologics License Application for Sprycel (dasatinib) in combination with chemotherapy for the treatment of pediatric patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia.

30 Aug 2018

Hesperos receives SBIR grant to create ‘human-on-a-chip’ model to mimic Alzheimer's disease

Hesperos, Inc., announced today the receipt of a NIH Phase I Small Business Innovation Research grant from the National Institutes of Health National Institute on Aging to help create a new multi-organ "human-on-a-chip" model that can realistically mimic the biology of Alzheimer's Disease and the effects of potential new therapies under realistic human physiological conditions.

29 Aug 2018

Scientists develop new cloaking metamaterial to improve accuracy of nano-sensors

An international research group of scientists from Politecnico di Torino and NUST MISIS has developed a model of a new metamaterial, which will improve the accuracy of nano-sensors in optics and biomedicine by cloaking them from external radiation.

29 Aug 2018

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

Pulmonary fibrosis is one of the most common and serious types of lung disease. Now NIBIB-funded researchers have developed an in vitro lung tissue-on-a-chip system that mimics lung fibrosis, offering rapid testing of potential new anti-fibrotic treatments.

28 Aug 2018

New findings reveal potential role of interleukin-1 alpha in risk for heart attacks, strokes

XBiotech Inc. announced today the publication of findings that point toward a white blood cell-derived interleukin-1 alpha (IL-1⍺) as a cause of blood clots that could lead to heart attacks or strokes.

28 Aug 2018

Biochemist's startup secures license for developing technology that could treat PTSD

A biochemist's startup company announced Monday that it had secured an exclusive patent license agreement with the Air Force Research Laboratory for a breakthrough technology that could help military veterans suffering from a post-traumatic stress disorder.

28 Aug 2018

Pregnant women with heart disease must give birth at 40 weeks gestation

Pregnant women with heart disease should give birth at no later than 40 weeks gestation. That is one of the recommendations in the 2018 European Society of Cardiology Guidelines for the management of cardiovascular diseases during pregnancy published online today in European Heart Journal, and on the ESC website.

25 Aug 2018

Research into biology behind sperm development could offer hope for solving male infertility

Nearly one in eight couples in the U.S. face infertility, and about half of those cases can be attributed to semen abnormalities in the male partner.

24 Aug 2018

Far-UVC light could help prevent catheter-based and driveline infections

A specific wavelength of ultraviolet light, now delivered through light-diffusing optical fibers, is highly effective at killing drug-resistant bacteria in cell cultures, according to a new study led by David J. Brenner, PhD, a professor of radiation biophysics at Columbia University Vagelos College of Physicians and Surgeons.

24 Aug 2018

'Plastic antibodies' effectively target and eliminate tumor cells

A joint research team from Russia and the U.K. has demonstrated the possibility of developing a new type of anti-neoplastic drugs based on nanoMIPs, or "plastic antibodies." NanoMIPs are synthetic polymers that can function as antibodies, selectively binding to target proteins on the surface of cancer cells.

23 Aug 2018

Researchers describe how RNA polymerase detects UV light damage in DNA

Damage to DNA is a constant threat to cellular life, and so it is constantly monitored and detected by a family of enzymes called RNA polymerases, resulting in subsequent repair to maintain genome integrity.

23 Aug 2018

Genetic variants impact outcome in dilated cardiomyopathy patients of African ancestry

Genetic testing is a powerful diagnostic tool that is increasingly being used for the diagnosis of dilated cardiomyopathy, a disease in which the heart becomes enlarged, making it difficult to pump blood. Cardiomyopathy affects more than 3.5 million people in the United States.

22 Aug 2018

Scientists design biomaterial that stimulates growth of blood vessels in teeth after root canal

A root canal ranks high on most people's list of dreaded dental procedures. Although the lengthy and sometimes painful surgery relieves the agony of an infection, a root canal results in a dead tooth with no living soft tissue, or dental pulp, inside.

22 Aug 2018

New minimally invasive therapy shows promise for long-term reversal of Type 1 diabetes

What if instead of daily insulin injections or wearing pumps, just getting a shot every few months could reverse Type 1 diabetes for you - or your dog?

21 Aug 2018

Study investigates whether fresh or frozen embryo transfer is best for women undergoing IVF

The world's first baby born via in-vitro fertilization turned 40 years old this summer. Still, after four decades, IVF is a relatively new field with ongoing debate on how to get the best results for families who have placed their hopes -- and often their personal savings -- into fertility treatment.

21 Aug 2018

Aravive Biologics gains Fast Track Designation for AVB-S6-500 from U.S. FDA

Aravive Biologics, Inc. announced today that the U.S. Food and Drug Administration has granted Fast Track Designation to AVB-S6-500 as a potential treatment for platinum-resistant recurrent ovarian cancer.

20 Aug 2018

Thrombospondin-1 contributes to development of aortic aneurysm in mice and humans, study finds

Researchers centered at the University of Tsukuba and Kansai Medical University in Japan reveal matricellular protein Thrombospondin-1 (Thbs1) contributes to the development of aortic aneurysm in mice and humans.

20 Aug 2018

in vitro News and Research

Likelihood of IVF success increases if 18 to 20 eggs are collected

A genetic signal-transmission system for the gut microbiome

Celmatix and Ferring announce genomics collaboration aimed at uncovering new insights into ovarian biology

FDA accepts Bristol-Myers Squibb’s application for Sprycel for treating pediatric leukemia

Hesperos receives SBIR grant to create ‘human-on-a-chip’ model to mimic Alzheimer's disease

Scientists develop new cloaking metamaterial to improve accuracy of nano-sensors

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

New findings reveal potential role of interleukin-1 alpha in risk for heart attacks, strokes

Biochemist's startup secures license for developing technology that could treat PTSD

Pregnant women with heart disease must give birth at 40 weeks gestation

Research into biology behind sperm development could offer hope for solving male infertility

Far-UVC light could help prevent catheter-based and driveline infections

'Plastic antibodies' effectively target and eliminate tumor cells

Researchers describe how RNA polymerase detects UV light damage in DNA

Genetic variants impact outcome in dilated cardiomyopathy patients of African ancestry

Scientists design biomaterial that stimulates growth of blood vessels in teeth after root canal

New minimally invasive therapy shows promise for long-term reversal of Type 1 diabetes

Study investigates whether fresh or frozen embryo transfer is best for women undergoing IVF

Aravive Biologics gains Fast Track Designation for AVB-S6-500 from U.S. FDA

Thrombospondin-1 contributes to development of aortic aneurysm in mice and humans, study finds

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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