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Uncovering how a key inflammatory molecule causes esophageal smooth muscle contractions

A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has uncovered important details about how platelet-activating factor (PAF)-a powerful molecule involved in inflammation and allergic reactions-triggers contractions in the smooth muscles of the esophagus.

9 Jul 2025

Exercise improves cancer outcomes by shaping the gut microbiome

A new study from the University of Pittsburgh shows for the first time how exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome.

9 Jul 2025

Single-cell sequencing maps immune changes in chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a hematopoietic malignancy characterized by BCR-ABL1 gene fusion.

9 Jul 2025

Retinal organoid model advances understanding of dry age-related macular degeneration

Age-related macular degeneration (AMD), classified into dry and wet types, poses a significant threat to the vision of the elderly population globally.

9 Jul 2025

New Scientific Statement outlines future research directions for type 1 diabetes

A new Scientific Statement released today by the Endocrine Society highlights potential research directions related to the pathogenesis of type 1 diabetes (T1D) that should help with the development of new and improved treatment options.

9 Jul 2025

Mapping vulnerability or resilience in Alzheimer's through imaging and genetics

It's been recognized for some time that Alzheimer's disease affects brain regions differently and that tau - a protein known to misbehave - plays an important role in the disease.

9 Jul 2025

Energy waves on cancer cell surfaces linked to tumor growth and aggressiveness

In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine say they have shed new light on the location and function of power-generating waves on the covering, or membrane, of these cells.

9 Jul 2025

SPT Labtech and Semarion collaborate to advance automated cell-based assay workflows

SPT Labtech, a global leader in innovative laboratory automation, today announced a strategic collaboration with Semarion, a University of Cambridge spin-out company from the Cavendish Laboratory combining materials engineering and cell biology to tackle unmet drug screening needs.

9 Jul 2025

Research reveals Ghanaian children face high cancer risk from local fish

Researchers found that most fish sampled from Ghana’s Keta Lagoon had arsenic and mercury levels exceeding World Health Organization limits. Health risk assessments show these contaminants pose significant cancer and non-cancer risks, especially for children.

8 Jul 2025

Artificial intelligence tracks aging and damaged cells through high resolution imaging

A combination of high-resolution imaging and machine learning, also known as artificial intelligence (AI), can track cells damaged from injury, aging, or disease, and that no longer grow and reproduce normally, a new study shows.

8 Jul 2025

UCLA researchers discover new way to prevent immunotherapy-induced type 1 diabetes

A team of researchers at the UCLA Health Jonsson Comprehensive Cancer Center has identified a potential new strategy to prevent, and even reverse, immune checkpoint inhibitor–induced type 1 diabetes, a rare but life-threatening side effect of cancer immunotherapy, using an existing class of autoimmune drugs.

8 Jul 2025

Vanderbilt and Parse Biosciences team up to develop antibody treatments for measles

Vanderbilt University Medical Center and Parse Biosciences, an innovator in single-cell sequencing, are collaborating on a new treatment to help unvaccinated measles victims, as the U.S. measles outbreak has now reached its highest case count in 30 years.

8 Jul 2025

Stem cells transform into bone cells by squeezing through narrow spaces

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing through narrow spaces.

8 Jul 2025

Understanding the human brain architecture through gene coexpression analysis

In a comprehensive Genomic Press Interview published in Brain Medicine, Dr. Michael C. Oldham shares his unconventional journey from advertising executive to computational neuroscientist and his groundbreaking contributions to understanding the human brain's cellular and molecular architecture through gene coexpression analysis.

8 Jul 2025

New RNA-based liquid biopsy detects early colorectal cancer with high accuracy

Liquid biopsies are tests that detect signs of cancer through a simple blood draw. Unlike traditional biopsies, which require removing a piece of tissue, a liquid biopsy typically looks for mutations or modification changes in fragments of DNA from cancer cells circulating in the blood.

8 Jul 2025

New funding brings personalized CRISPR cures closer to children with rare diseases

Personalized CRISPR cures for children born with rare genetic diseases are now a step closer to being more widely available.

8 Jul 2025

KAIST scientists develop tool to fight drug resistance in cancer

One of the biggest obstacles in cancer treatment is drug resistance in cancer cells. Conventional efforts have focused on identifying new drug targets to eliminate these resistant cells, but such approaches can often lead to even stronger resistance.

8 Jul 2025

Aspartame triggers genetic changes tied to glioblastoma severity

Study shows aspartame affects gut microbiome and gene expression in glioblastoma, highlighting potential links to cancer progression and treatment strategies.

8 Jul 2025

Scientists uncover hidden superfamily of lipid trapping proteins in bacteria

Scientists have identified a new type of protein in bacteria that could change our understanding of how these organisms interact with their environments.

8 Jul 2025

Landmark discovery reshapes understanding of key cancer protein MCL-1

Landmark research on MCL-1, a critical protein that is an attractive target for cancer drug development, helps explain why some promising cancer treatments are causing serious side effects, and offers a roadmap for designing safer, more targeted therapies.

8 Jul 2025

Cell News and Research

Uncovering how a key inflammatory molecule causes esophageal smooth muscle contractions

Exercise improves cancer outcomes by shaping the gut microbiome

Single-cell sequencing maps immune changes in chronic myeloid leukemia

Retinal organoid model advances understanding of dry age-related macular degeneration

New Scientific Statement outlines future research directions for type 1 diabetes

Mapping vulnerability or resilience in Alzheimer's through imaging and genetics

Energy waves on cancer cell surfaces linked to tumor growth and aggressiveness

SPT Labtech and Semarion collaborate to advance automated cell-based assay workflows

Research reveals Ghanaian children face high cancer risk from local fish

Artificial intelligence tracks aging and damaged cells through high resolution imaging

UCLA researchers discover new way to prevent immunotherapy-induced type 1 diabetes

Vanderbilt and Parse Biosciences team up to develop antibody treatments for measles

Stem cells transform into bone cells by squeezing through narrow spaces

Understanding the human brain architecture through gene coexpression analysis

New RNA-based liquid biopsy detects early colorectal cancer with high accuracy

New funding brings personalized CRISPR cures closer to children with rare diseases

KAIST scientists develop tool to fight drug resistance in cancer

Aspartame triggers genetic changes tied to glioblastoma severity

Scientists uncover hidden superfamily of lipid trapping proteins in bacteria

Landmark discovery reshapes understanding of key cancer protein MCL-1

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